The Cancer Prevention and Research Institute of Texas approved 15 grants in November totaling nearly $18.4 million for North Texas researchers and institutions in its latest funding round, part of a statewide investment of almost $154 million announced Nov. 19.<\/p>\n
UT Southwestern Medical Center dominated the region\u2019s awards with 13 grants spanning recruitment, prevention, and research. UT Dallas captured two research grants.<\/p>\n
\u201cTexas has invested $4 billion in the fight against one of the world\u2019s greatest public health challenges,\u201d said CPRIT CEO Kristen Doyle, herself a cancer survivor.<\/p>\n
Doyle said the support has helped the state lead the search for breakthrough treatments, develop new cancer-fighting drugs and devices, and save \u201ctens of thousands of lives through early cancer detection and prevention.\u201d<\/p>\n
Dallas-Fort Worth CPRIT recipients and their respective categories include:<\/p>\n
Recruitment<\/p>\n
CPRIT awarded $2 million to UT Southwestern to recruit Elijah Mena to Dallas.<\/p>\n
Prevention<\/p>\n
UT Southwestern received two prevention grants totaling nearly $5 million.<\/p>\n
Keith E. Argenbright at UT Southwestern in Fort Worth received $2.5 million for \u201cIncreasing Access to Cervical Cancer Screening and Patient Navigation in North Texas.\u201d<\/p>\n
David Gerber UT Southwestern in Dallas received $2.4 million for \u201cIntegrated lung cancer screening and tobacco cessation.\u201d<\/p>\n
Research<\/p>\n
The research category drew 12 awards worth nearly $12 million.<\/p>\n
Saikat Mukhopadhyay at UT Southwestern in Dallas received $1.2 million for \u201cStudy of primary cilium maintenance as a dependency in SHH medulloblastoma.\u201d<\/p>\n
Jie Zheng at UT Dallas in Richardson received $900,000 for \u201cHigh-contrast fluorescence imaging of non-enhancing brain metastases.\u201d<\/p>\n
Payal Kapur at UT Southwestern in Dallas received $1 million for \u201cAdvancing Clinical Decision-Making through Machine Learning on Underutilized Data.\u201d<\/p>\n
Tao Yue at UT Southwestern in Dallas received $900,000 for \u201cOvercoming Immunotherapy Resistance for the Treatment of Renal Cell Carcinoma.\u201d<\/p>\n
Michalis Agathocleous at UT Southwestern in Dallas received $900,000 for \u201cMechanisms of blood cancer suppression by ascorbate.\u201d<\/p>\n
YI LI at UT Dallas in Richardson received $899,216 for \u201cAntisense Oligonucleotide Targeting Strategies for NAB2-STAT6 Solitary Fibrous Tumors.\u201d<\/p>\n
Tuoqi Wu at UT Southwestern in Dallas received $1.2 million for \u201cTarget the Redox Sensing Pathway to Enhance Anti-Tumor T-cell Immunity.\u201d<\/p>\n
Deepak Nijhawan at UT Southwestern in Dallas received $898,004 for \u201cDevelopment of tumor activated IMPDH inhibitors to treat glioblastoma.\u201d<\/p>\n
Zhenyu Zhong at UT Southwestern in Dallas received $900,000 for \u201cSympathetic Innervation Controls the Development of Obesity-Associated Liver Cancer.\u201d<\/p>\n
Gerta Hoxhaj at UT Southwestern in Dallas received $900,000 for \u201cDecoding Compartmentalized Redox Metabolism in Melanoma Metastasis.\u201d<\/p>\n
Kathryn O\u2019Donnell at UT Southwestern in Dallas received $900,000 for \u201cOncogenic activity and therapeutic targeting of serine protease TMPRSS11B in lung cancer.\u201d<\/p>\n
David Gerber at UT Southwestern in Dallas received $894,790 for \u201cMechanisms and treatment of immunotherapy toxicity.\u201d<\/p>\n
The statewide funding round approved 73 grants and pushed CPRIT\u2019s total investment past $4 billion, making Texas the largest state funder of cancer research in the nation. CPRIT stands as the second-largest funder of cancer research in the country after the National Cancer Institute.<\/p>\n
\u201cEvery Texan should know this effort matters, and we\u2019re not finished yet,\u201d Doyle said. \u201cTogether, we will conquer cancer.\u201d<\/p>\n
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