The unofficial midway point of the 2025 college football season begins on Saturday with plenty of intriguing matchups in Week 8. Twenty-three of the teams ranked in the latest AP Top 25 poll will be in action this weekend, including five ranked-on-ranked matchups.

The fun began in Nashville when No. 17 Vanderbilt hosts No. 10 LSU. The Commodores are favored (-2.5) over the Tigers, which will mark the first time since at least 1978 that the program is a favorite over a ranked opponent.

No. 1 Ohio State will be in action at 3:30 p.m. ET on CBS against Wisconsin. Also in the same window, No. 5 Ole Miss faces No. 9 Georgia and No. 3 Indiana, fresh off a marquee win over Oregon, has a date against Michigan State.

The late window is where chaos could ensue. It’s the third Saturday in October, and that means No. 11 Tennessee will face No. 6 Alabama in a game with major CFP implications. No. 20 USC is coming off one of the biggest wins of the Lincoln Riley era, and will look to stay hot against No. 13 Notre Dame on the road.

One of the final ranked games of the day is a good one, as No. 23 Utah faces No. 15 BYU in the Holy War. BYU is currently tied for first place in the Big 12 with Texas Tech and Cincinnati after starting conference play 3-0.

CBS Sports will be here every step of the way to update you with the latest scores, highlights and storylines throughout the evening. All times Eastern

College football scores, schedule: Week 7

No. 10 LSU at No. 17 Vanderbilt — noon on ABC 
No. 14 Oklahoma at South Carolina  — 12:45 p.m. — SEC Network
No. 1 Ohio State at Wisconsin — 3:30 p.m. — CBS Expert picks, preview
No. 5 Ole Miss at No. 9 Georgia — 3:30 p.m. — ABC Expert picks, preview
No. 7 Texas Tech at Arizona State — 4 p.m. — FOX Expert picks, preview
No. 11 Tennessee at No. 6 Alabama — 7:30 p.m. — ABC Expert picks, preview
No. 20 USC at No. 13 Notre Dame — 7:30 p.m. — NBC/Peacock Expert picks, preview
No. 23 Utah at No. 15 BYU — 8 p.m. — FOX

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