The game at Emirates Stadium comes amid a hectic fixture schedule, with Mikel Arteta expected to rotate his side at Emirates Stadium.
But the Gunners are eyeing a spot in the quarter-finals as they bid to continue their momentum after a run of seven straight wins in all competitions.
Brighton have made an inconsistent start in the Premier League and sit 13th after losing 4-2 at Manchester United on Saturday.
Here’s everything you need to know about the game…
Date, kick-off time and venue
Arsenal vs Brighton in the Carabao Cup fourth round is scheduled for a 7:45pm GMT kick-off on Wednesday October 29, 2025.
The match will take place at the Emirates Stadium in north London.
Where to watch Arsenal vs Brighton
TV channel: In the UK, the game will be televised live on Sky Sports+, with coverage beginning at 7:45pm.
Live stream: Sky Sports subscribers can also catch the contest live online via the Sky Go app.
Live blog: You can follow all the action on matchday via Standard Sport’s live blog, with expert analysis from Arsenal correspondent Simon Collings at the Emirates.
Arsenal vs Brighton team news
Gabriel Magalhaes shook off a knock to play the full 90 minutes at the weekend, though captain Martin Odegaard, Noni Madueke, Kai Havertz and Gabriel Jesus all remained out. Bukayo Saka is available despite struggling with illness last week.
Ruled out: William Saliba is sidelined after suffering an injury against Crystal Palace on Sunday
Arsenal FC via Getty Images
Arteta is set to rotate heavily again as he did at Port Vale in round three, with Deadline Day signing Piero Hincapie in line for a full debut in addition to chances for the likes of Kepa Arrizabalaga, Ben White, Cristhian Mosquera, Myles Lewis-Skelly, Ethan Nwaneri, Mikel Merino, Christian Norgaard and Max Dowman.
Adam Webster, Solly March and Jack Hinshelwood are all long-term absentees for the Seagulls.
Arsenal vs Brighton prediction
It may not always be easy on the eye, but Arsenal are about as efficient as it gets right now.
Set-piece masters who have still conceded only three goals all season and just one from open play, they are grinding out wins domestically and taking advantage of crisis-stricken Liverpool’s repeated slip-ups.
It will be intriguing to see if a presumably heavily-rotated team can produce a similar performance as Arteta takes advantage of his new-found depth, with Brighton capable of beating anyone on their day despite an inconsistent start to the season under Fabian Hurzeler.
Head to head (h2h) history and results
Arsenal vs Brighton match odds
Arsenal to go through: 1/6
Brighton to go through: 7/2
Odds via Betfair (subject to change).