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NEED TO KNOWFILE - The injectable drug Ozempic is shown, July 1, 2023, in Houston. (AP Photo/David J. Phillip, File)

David J. Phillip/AP

New medical guidelines and research released this week could reshape how we approach some of the most important issues in health care today. Here’s what to know.

GLP-1 guidelines: The World Health Organization recommended that semaglutide therapies like Ozempic and Wegovy may be used to treat obesity in adults, alongside diet and exercise changes. The drugs are so popular that states funding them through Medicaid are facing budgetary issues. [Today/Politico]

Smartphone risks: A new study that analyzed data on more than 10,000 teens found that kids who own a smartphone before 12 years old may face a greater risk of mental health issues, poor sleep and obesity. [CBS News]

HIV treatments: New HIV studies highlight the routes scientists are taking to cure the virus. One small study found that an initial round of immunotherapy could control the virus in most patients for months without taking daily pills. “This is unexpected and unparalleled,” one researcher said. [Washington Post]

IN CASE YOU MISSED ITLuigi Mangione, center, appears in court for an evidence hearing, Monday, Dec. 1, 2025, in New York. (Steven Hirsch/New York Post via AP, Pool)

Steven Hirsch/New York Post via AP

Mangione pretrial hearing opens

At a pretrial hearing yesterday, lawyers for Luigi Mangione, who has pleaded not guilty to murder charges in the killing of United Healthcare CEO Brian Thompson, sought to throw out key evidence. New details of the 911 call that led to his arrest were also revealed. [CNN]

Major Northeast snowstorm

After pummeling the Midwest, a winter storm that’s tracking eastward is forecast to bring up to 10 inches of snow to parts of the Northeast today, potentially causing travel disruptions. Are you in the region? See advisories for your area. [AP/Weather Channel]

New TSA fee

The Transportation Security Administration said that starting on Feb. 1, 2026, travelers who go through airport security without a Real ID or passport will face a $45 fee — up from a proposed $18 last month. [Yahoo News]

‘Stranger Things’ changes

Since Volume 1 of Stranger Things Season 5 dropped last week, fans have taken to social media to call out continuity errors between the latest episodes and past history. Meanwhile, in a recent interview, star Millie Bobby Brown revealed her new name. [Entertainment Weekly]

Patriots’ ‘MNF’ blowout

The Patriots routed the Giants 33-15, winning most of those points before halftime. In a sign of the Giants’ struggles this season, kicker Younghoe Koo had a botched field goal for the ages, kicking the turf instead of the ball. See the flub. [Yahoo Sports]

WHAT’S HAPPENING TODAYMatt Van Epps and Aftyn Behn. (Photo illustration: Yahoo News; photos: George Walker IV/AP)

Matt Van Epps and Aftyn Behn. (Photo illustration: Yahoo News; photos: George Walker IV/AP)

At the ballot box

Tennessee voters will decide between Republican Matt Van Epps and Democrat Aftyn Behn in a special election for a typically deep-red U.S. House district. The race has been surprisingly tight. Here’s why President Trump said the “whole world is watching” this one. [Yahoo News]

Now streaming

Sean Combs: The Reckoning, rapper 50 Cent’s four-part documentary about the imprisoned music mogul known as Diddy, dropped on Netflix. It comes hours after Combs called it a “hit piece” with “stolen footage” and his lawyers sent a cease-and-desist letter. [CNN]

On TV

For festive vibes, catch Megan Moroney, Jordan Davis, Lady A and others performing on CMA Country Christmas at 9 p.m. ET on ABC. Or tune in to the Vanderpump Rules Season 12 premiere, airing at the same time on Bravo. Meet the new cast. [Variety/Cosmopolitan]

On the court

The Thunder, who have won 20 of 21 games so far this season thanks to star Shai Gilgeous-Alexander, face the Warriors at 11 p.m. ET on Peacock. [Yahoo Sports]

And don’t forget to…

Read your daily horoscope. Play the crossword. Check the forecast in your area.

TODAY IN HISTORYIllustration: Yahoo News; photo: MCA/Universal/Courtesy Everett Collection

Illustration: Yahoo News; photo: MCA/Universal/Courtesy Everett Collection

In 1983, the groundbreaking 14-minute-long music video for Michael Jackson’s “Thriller” premiered on MTV. The song reached No. 10 on the Billboard Hot 100 last month, making the King of Pop the only artist to rise to the top 10 in six different decades. Here’s why it continues to chart over 40 years later. [Billboard]

FEEL-GOOD MOMENTrachelpetrasanon/TikTok

rachelpetrasanon/TikTok

Rachel Sanon’s late grandmother couldn’t be there for her granddaughter’s wedding, but she was there in spirit after Rachel’s husband, Eli, got each of his groomsmen to wear one of her brooches at the ceremony. “I immediately started crying,” Rachel said about the surprise. [People]

💡 P.S. Your daily advice: If you’re weighing “Travel Tuesday” deals, do your research. In some cases, prices may be artificially inflated, or there may be fine print attached to offers. [AP]

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