Banksy enthusiast Jason Tomkins, said he also believed it was a “clear statement on homelessness”.
The Centre Point tower, at 101-103 New Oxford Street, has been a historic focal point for housing protests.
Originally built as an office block in 1963, the Centre Point tower next to Tottenham Court Road underground station, remained unoccupied for over a decade, angering social justice campaigners.
The homelessness charity Centrepoint was named as a response to the building by founder Rev Ken Leech, who described the tower as “an affront to the homeless”.
The block has since been converted into multimillion-pound luxury flats.
Banksy has not commented on the relevance of the location for either of the new works.