As potential therapies are being investigated for the treatment of vitiligo, it is safe to predict that the treatment space will significantly impact the vitiligo market during the forecast period. Moreover, the anticipated introduction of emerging therapies with improved efficacy and a further improvement in the diagnosis rate are expected to drive the growth of the vitiligo market in the 7MM.
However, several factors may impede the growth of the vitiligo market. While existing therapies for vitiligo can induce repigmentation, the results are often partial and temporary with high relapse rates after discontinuation; despite not being life-threatening, vitiligo’s visible effects frequently cause stigma, anxiety, and depression, severely impacting mental health and quality of life, while insurance barriers, such as classifying treatments like OPZELURA or light therapy as ‘cosmetic’, force patients to bear the costs, and cultural stigma, particularly in parts of Asia where vitiligo is wrongly linked to leprosy or bad luck, leads to discrimination in education, employment, and marriage.
Moreover, vitiligo treatment poses a significant economic burden and disrupts patients’ overall well-being and QOL. Furthermore, the vitiligo market growth may be offset by failures and discontinuation of emerging therapies, unaffordable pricing, market access and reimbursement issues, and a shortage of healthcare specialists. In addition, the undiagnosed, unreported cases and the unawareness about the disease may also impact the vitiligo market growth.
Vitiligo Treatment Market
Vitiligo treatment focuses on restoring skin pigmentation and enhancing appearance, though outcomes may be temporary and may not halt disease progression. Initial care by a general physician often involves sun protection, camouflage cosmetics, and topical corticosteroids for mild non-segmental vitiligo. If specialized treatment is required, dermatologists may recommend calcineurin inhibitors, phototherapy, or surgical interventions such as skin grafting for stable cases.
For widespread vitiligo, depigmentation therapies may be considered. Due to limited sun exposure, vitamin D supplementation is often advised. Emotional support through counseling, support groups, or cognitive behavioral therapy (CBT) can help manage psychological effects. Some treatments, though unlicensed, may be suggested when potential benefits surpass risks.
OPZELURA (ruxolitinib cream), a topical JAK inhibitor, is the first and only FDA-approved therapy specifically for non-segmental vitiligo in individuals aged 12 and above, marking a major breakthrough in targeted immunotherapy for this condition.
To know more about FDA-approved drugs for vitiligo, visit @ Approved Vitiligo Treatment
Vitiligo Pipeline Therapies and Key Companies
Vitiligo pipeline possesses some drugs in mid- and late stage developments to be approved in the near future. Expected launch of emerging therapies, such as LITFULO (Pfizer), RINVOQ (upadacitinib) (AbbVie), Povorcitinib (INCB54707) (Incyte Corporation), and others shall further create a positive impact on the vitiligo treatment market.
LITFULO (ritlecitinib)Â targets JAK3 and TEC family kinases, and its inhibition of these kinases may disrupt cytokine signaling and reduce the cytolytic function of T cells. LITFULO is currently undergoing Phase III clinical trials as a potential therapy for vitiligo, a chronic autoimmune disorder that leads to the destruction of pigment-producing cells, causing white patches on the skin.
RINVOQ, a JAK inhibitor developed by AbbVie, has received approval for seven indications and is being explored for various immune-mediated conditions. A Phase III clinical study is currently assessing RINVOQ in adults and adolescents with nonsegmental vitiligo who qualify for systemic treatment.
The anticipated launch of these emerging therapies are poised to transform the vitiligo market landscape in the coming years. As these cutting-edge therapies continue to mature and gain regulatory approval, they are expected to reshape the vitiligo market landscape, offering new standards of care and unlocking opportunities for medical innovation and economic growth.
Discover more about vitiligo marketed and pipeline drugs @ Vitiligo Clinical Trials
Recent Developments in the Vitiligo Market
In January 2025, VYNE Therapeutics Inc. completed patient enrollment in its Phase 2b study assessing VYN201 gel for nonsegmental vitiligo. Top-line results from the 24-week vehicle-controlled treatment phase are anticipated by mid-2025.
Vitiligo Overview
Vitiligo is a chronic skin condition characterized by the loss of melanin, the pigment responsible for skin, hair, and eye color. It occurs when melanocytes, the pigment-producing cells, are destroyed or stop functioning. The exact cause of vitiligo is not fully understood, but it is believed to involve a combination of genetic, autoimmune, and environmental factors. In autoimmune cases, the body’s immune system mistakenly attacks melanocytes. Common triggers include stress, sunburn, or exposure to certain chemicals.
The primary symptom of vitiligo is the appearance of white or depigmented patches on the skin, which can occur on any part of the body. These patches are more noticeable in people with darker skin tones. Other symptoms may include premature graying of scalp or facial hair, color loss in the tissues inside the mouth and nose, and changes in eye color.
Diagnosis of vitiligo is usually based on clinical examination by a dermatologist. Wood’s lamp examination, which uses ultraviolet light, can help highlight affected areas that are not visible to the naked eye. In some cases, a skin biopsy or blood tests may be conducted to rule out other conditions or to check for autoimmune disorders associated with vitiligo.
Vitiligo Epidemiology Segmentation
The vitiligo epidemiology section provides insights into the historical and current vitiligo patient pool and forecasted trends for the 7MM. It helps recognize the causes of current and forecasted patient trends by exploring numerous studies and views of key opinion leaders.
The vitiligo market report proffers epidemiological analysis for the study period 2020–2034 in the 7MM, segmented into:
Total Prevalent Cases of Vitiligo
Total Diagnosed Prevalent Cases of Vitiligo
Gender-specific Cases of Vitiligo
Type-specific Cases of Vitiligo
Age-specific Cases of Vitiligo
Total Treated Cases of Vitiligo
Vitiligo Market Report Metrics
Details
Study Period
2020–2034
Coverage
7MM [The United States, the EU4 (Germany, France, Italy, and Spain) and The United Kingdom, and Japan].
Vitiligo Market CAGR
9.6Â %
Vitiligo Market Size in 2024
USD 1.1 Billion
Key Vitiligo Companies
Pfizer, AbbVie, Incyte Corporation, Vyne Therapeutics, Clinuvel, and others
Key Vitiligo Therapies
LITFULO (ritlecitinib), RINVOQ (upadacitinib), Povorcitinib (INCB54707), Repibresib Gel (VYN201), SCENESSE (Afamelanotide), and others
Scope of the Vitiligo Market Report
Therapeutic Assessment: Vitiligo current marketed and emerging therapies
Vitiligo Market Dynamics: Key Market Forecast Assumptions of Emerging Vitiligo Drugs and Market Outlook
Competitive Intelligence Analysis:Â SWOT analysis and Market entry strategies
Unmet Needs, KOL’s views, Analyst’s views, Vitiligo Market Access and Reimbursement
Download the report to understand which factors are driving vitiligo treatment market trends @ Vitiligo Market Forecast
Table of Contents
1
Key Insights
2
Report Introduction
3
Vitiligo Market Overview at a Glance
3.1
Market Share (%) Distribution of vitiligo by Country in 2024 in the 7MM
3.2
Market Share (%) Distribution of Vitiligo by Country in 2034 in the 7MM
4
Methodology
5
Executive Summary
6
Key Events
7
Disease Overview and Background
7.1
Introduction
7.2
Causes and Risk Factors of Vitiligo
7.3
Clinical Manifestations of Vitiligo
7.4
Associated Disorders With Vitiligo
7.5
Classification of Vitiligo
7.6
Pathophysiology of Vitiligo
7.7
Diagnosis
7.8
Differential Diagnosis
7.9
Diagnostic Guidelines
7.9.1
British Association of Dermatologists Guidelines for the Diagnosis of People With Vitiligo 2021
7.9.2
Worldwide Expert Recommendations for the Diagnosis of Vitiligo (International Vitiligo Task Force)
7.9.3
Journal of the German Society of Dermatology, 2022
7.9.4
Guidelines for the Diagnosis of Vitiligo in Japan
8
Treatment and Management of Vitiligo
8.1
Treatment Guidelines
8.1.1
British Association of Dermatologists Guidelines for the Management of People with Vitiligo 2021
8.1.2
Worldwide Expert Recommendations for the Management of Vitiligo (International Vitiligo Task Force)
8.1.3
Journal of the German Society of Dermatology, 2022
8.1.4
Guidelines for the Diagnosis and Treatment of Vitiligo in Japan
8.2
Treatment Algorithm
9
Epidemiology and Patient Population
9.1
Key Findings
9.2
Assumptions and Rationale 7MM
9.3
Total Prevalence Cases of Vitiligo in the 7MM
9.4
The United States
9.4.1
Total Prevalent Cases of Vitiligo in the United States
9.4.2
Total Diagnosed Prevalence Cases of Vitiligo in the United States
9.4.3
Gender-specific Cases of Vitiligo in the United States
9.4.4
Type-specific Cases of Vitiligo in the United States
9.4.5
Age-specific Cases of Vitiligo in the United States
9.4.6
Total Treated Cases of Vitiligo in the United States
9.5
EU4 and the UK
9.5.1
Total Prevalent Cases of Vitiligo in EU4 and the UK
9.5.2
Total Diagnosed Prevalence Cases of Vitiligo in EU4 and the UK
9.5.3
Gender-specific Cases of Vitiligo in EU4 and the UK
9.5.4
Type-Specific Cases of Vitiligo in EU4 and the UK
9.5.5
Age-specific Cases of Vitiligo in EU4 and the UK
9.5.6
Total Treated Cases of Vitiligo in EU4 and the UK
9.6
Japan
9.6.1
Total Prevalent Cases of Vitiligo in Japan
9.6.2
Total Diagnosed Prevalence Cases of Vitiligo in Japan
9.6.3
Gender-specific Cases of Vitiligo in Japan
9.6.4
Type-Specific Cases of Vitiligo in Japan
9.6.5
Age-specific Cases of Vitiligo in Japan
9.6.6
Total Treated Cases of Vitiligo in Japan
10
Patient Journey
11
Marketed Therapies
11.1
OPZELURA (ruxolitinib): Incyte Corporation
11.1.1
Product Description
11.1.2
Regulatory Milestones
11.1.3
Other Developmental Activities
11.1.4
Clinical Development
11.1.5
Safety and Efficacy
12
Emerging Therapies
12.1
Key Cross Competition
12.2
LITFULO (ritlecitinib): Pfizer
12.2.1
Product Description
12.2.2
Other Developmental Activities
12.2.3
Clinical Developmental Activities
12.2.4
Safety and Efficacy
12.2.5
Analyst View
12.3
RINVOQ (upadacitinib): AbbVie
12.4
Povorcitinib (INCB54707): Incyte Corporation
12.5
Repibresib Gel (VYN201): Vyne Therapeutics
12.6
SCENESSE (Afamelanotide): Clinuvel
13
Vitiligo: 7 Major Market Analysis
13.1
Key Findings
13.2
Market Outlook
13.3
Conjoint Analysis
13.4
Key Market Forecast Assumptions
13.5
Market Size of Vitiligo in the 7MM
13.6
Market Size of Vitiligo by Therapies in the 7MM
13.7
The United States
13.7.1
Total Market Size of Vitiligo in the United States
13.7.2
Market Size of Vitiligo by Therapies in the United States
13.8
EU4 and the UK
13.8.1
Total Market Size of Vitiligo in EU4 and the UK
13.8.2
Market Size of Vitiligo by Therapies in EU4 and the UK
13.6
Japan
13.6.1
Total Market Size of Vitiligo in Japan
13.6.2
Market Size of Vitiligo by Therapies in Japan
14
KOL Views
15
SWOT Analysis
16
Unmet Needs
17
Market Access and Reimbursement
17.1
United States
17.2
EU4 and the UK
17.3
Japan
17.4
Market Access and Reimbursement Scenario in Vitiligo
18
Bibliography
19
Report Methodology
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SOURCE DelveInsight Business Research, LLP