Ahmedabad: A few years ago, a woman visited the outpatient department (OPD) of AIIMS Delhi, complaining of persistent fatigue. Upon conducting tests, doctors discovered that her heart was functioning significantly below optimal levels. During her consultation, she revealed that her brother had died young, and her aunt had experienced a similar fate. This prompted Dr. Sandeep Seth, Professor of Cardiology at AIIMS Delhi, to investigate potential genetic links and assess whether other family members might be at risk.Dr Seth shared this story at the Cardiovascular Research Convergence (CRC) 2025 event, held at the Gujarat Biotechnology University (GBU) in collaboration with the UN Mehta Institute of Cardiology and Research Centre (UNMICRC). “We identified the underlying genetic condition in the woman and found similar genetic profiles in other family members,” Dr Seth explained. “We recommended the use of an Implantable Cardioverter Defibrillator (ICD) to prevent arrhythmia episodes, which can lead to sudden death. This case highlights how understanding genetic conditions can provide new perspectives on cardiovascular diseases,” he added.CRC 2025, which took place over the weekend, attracted over 250 delegates from across India, including medical students and scientists. Dr Seth, along with Dr S K Maulik from AIIMS Delhi, founded the CRC Society to promote collaboration between cardiologists, cardiac surgeons, and other scientific disciplines for effective ‘bench to bedside’ implementation. Dr Subeer Majumdar, director general of GBU, said that the event featured live case discussions, with experts from various fields offering their insights.Some of the overarching themes included cardiometabolic disorders, cardiotherapeutics, AI in biotechnology, coronary artery diseases and heart failure. Case studies presented by the experts covered a range of topics from CAR-T cell therapy to long-Covid effects.
