The Indiana Pacers will look to pick up their first win of the season when they tip off against the Memphis Grizzlies.
Pascal Siakam was all over the box score in his season opener, and I’m expecting another big night for Spicy P in my Pacers vs. Grizzlies predictions and NBA picks for tonight’s game.
Advertisement
Want to make sure Covers shows up often in your Google search results and Discover feed?
Simply click here and add Covers as one of your “source preferences”.
Pacers vs Grizzlies prediction
Pacers vs Grizzlies best bet: Pascal Siakam Over 22.5 points (-115)
The Indiana Pacers opened the season against the Thunder on Thursday in a rematch of last year’s NBA Finals, coming up short 141-135 in double overtime.
Bennedict Mathurin came out hot with a team-high 36 points while Pascal Siakam dropped 32 points of his own (28 in regulation time) and added 15 boards.
Siakam went 12-for-25 from the field, with his 12 makes and 25 attempts leading the Pacers and trailing only Shai Gilgeous-Alexander (15-for-31) for tops among all players in the game.
Advertisement
I’m expecting Spicy P to take control of the game again tonight against the Memphis Grizzlies, who haven’t looked too interested in playing defense.
Memphis is allowing 134 points per game through its first two contests of 2025-26 and finished tied for sixth-last in the NBA in opponent points allowed last season (116.9).
Pacers vs Grizzlies same-game parlay
Siakam was a beast all over the court in Indiana’s season opener and could crush these lines against a lackadaisical Grizzlies defense.
Memphis has allowed 52 opponent rebounds per game in this early season – the third-worst mark in the NBA.
Advertisement
If Siakam and Mathurin both show out again, I like the underdog Pacers to overpower Ja Morant’s Grizzlies.
Pacers vs Grizzlies SGP
Pascal Siakam Over 22.5 points
Pascal Siakam Over 7.5 rebounds
Our “from downtown” SGP: Pacers pack a punch
Siakam had a double-double against the Thunder, and tonight’s matchup against the Grizzlies should be an easier assignment. Spicy P recorded 13 double-doubles last season.
Mathurin went 3-for-8 from three-point range on Thursday and should comfortably drop at least a couple of treys against a Grizzlies team that’s allowing opponents to make 43.3% of their threes.
Pacers vs Grizzlies SGP
Pascal Siakam Over 22.5 points
Pascal Siakam Over 7.5 rebounds
Benedict Mathurin Over 1.5 threes
Pacers vs Grizzlies odds
Spread: Pacers +1 | Grizzlies -1
Moneyline: Pacers -105 | Grizzlies -115
Over/Under: Over 237.5 | Under 237.5
Advertisement
Pacers vs Grizzlies betting trend to know
The Grizzlies have gone Over the first-quarter total in 27 of their last 36 home games for +16.6 units and a 40% ROI. Find more NBA betting trends for Pacers vs. Grizzlies.
How to watch Pacers vs Grizzlies
Location
FedExForum, Memphis, TN
Date
Saturday, October 25, 2025
Tip-off
8:00 p.m. ET
TV
FDSN IN, FDSN SE-MEM
Pacers vs Grizzlies latest injuries
Not intended for use in MA.
Affiliate Disclosure: Our team of experts has thoroughly researched and handpicked each product that appears on our website. We may receive compensation if you sign up through our links.
This article originally appeared on Covers.com, read the full article here