What should have been a headline-worthy early-season matchup is now instead a showcase of second and third stars.

But Minnesota has the better supporting cast, led by Anthony Edwards’ career-long running mate. My Lakers vs. Timberwolves predictions focus on Jaden McDaniels, who is still underappreciated offensively.

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Here are my NBA picks for Wednesday, October 29.

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Lakers vs Timberwolves prediction

Lakers vs Timberwolves best bet: Jaden McDaniels Over 16.5 points (-115)

Jaden McDaniels has developed more of an offensive game than he is given credit for. Sure, he may have cleared this prop in only 19 of 82 games last season, but three of those 19 were the three games Anthony Edwards missed.

Add in Monday’s loss to the Nuggets, and McDaniels has averaged 24.5 points in his last four games without the Minnesota Timberwolves’ superstar.

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Both halves of that thought make sense. With Edwards, Minnesota has its focal point — with plenty of possessions intentionally set in the halfcourt — and McDaniels is left playing a more complementary offensive role.

Without Edwards, the Timberwolves target whatever mismatch is presented, live more in transition, and McDaniels thrives in both regards.

The defensive wing has scored at least 20 points in each of those four games without Edwards, something that should probably be expected tonight, but do not target that milestone too aggressively.

A blowout is not off the table while the Los Angeles Lakers lack their two best players, and Minnesota has a deep enough bench to cut short McDaniels’s night in any rout.

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Lakers vs Timberwolves same-game parlay

McDaniels took to shooting more 3-pointers when Anthony Edwards was sidelined last season, and that should continue to be an emphasis for McDaniels while Julius Randle initiates the offense.

The other emphasis for both McDaniels and the Timberwolves will be the other end of the court, where the team was called out by head coach Chris Finch for paltry defense this week. 

Slowing down the last viable Laker threat should be a surface-level demand of that public criticism.

Lakers vs Timberwolves SGP

Jaden McDaniels Over 16.5 points

Jaden McDaniels Over 1.5 threes

Austin Reaves Under 30.5 points

Our “from downtown” SGP: Bench depth

Terrence Shannon Jr. scores when he plays. His props do not need to be more complicated than that. And with Anthony Edwards out and Jaylen Clark questionable (calf strain), expect Shannon to play and score.

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Lakers vs Timberwolves SGP

Jaden McDaniels Over 16.5 points

Jaden McDaniels Over 1.5 threes

Austin Reaves Under 30.5 points

Terrence Shannon Jr. Over 8.5 points

Lakers vs Timberwolves odds

Spread: Lakers +7 | Timberwolves -7

Moneyline: Lakers +225 | Timberwolves -275

Over/Under: Over 225.5 | Under 225.5

Lakers vs Timberwolves betting trend to know

The Timberwolves are 0-4 against the spread this season, falling short of bookmakers’ expectations by an average of 8.6 points. Find more NBA betting trends for Lakers vs. Timberwolves.

How to watch Lakers vs Timberwolves

Location

Target Center, Minneapolis, MN

Date

Wednesday, October 29, 2025

Tip-off

9:30 p.m. ET

TV

ESPN

Lakers vs Timberwolves latest injuries

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