July 22, 2026 Updated 9:17 am EDT

Nathaniel Lowe rides a two-game homer streak into the Cincinnati Reds’ game against the Seattle Mariners at 3:40 p.m. ET on Wednesday, at T-Mobile Park. Emerson Hancock (6-4, 3.17 ERA) will start for the Mariners, who are 51-51 this season and second in the AL West. Brady Singer (4-9, 4.56 ERA) is the expected starter for the Reds, who are 46-54 and fifth in the NL Central.

How to watch Cincinnati Reds vs. Seattle MarinersReds vs. Mariners odds
Favorite Moneyline: Mariners -118
Underdog Moneyline: Reds -102
Total: 7.5
Total Over Odds: -110
Total Under Odds: -110
Injury reportsMariners

Brendan Donovan: 10 Day IL (Groin), Rob Refsnyder: 10 Day IL (Knee), Matt Brash: 15 Day IL (Lat), Cooper Criswell: 60 Day IL (Shoulder), Will Wilson: 60 Day IL (Thumb), Logan Evans: 60 Day IL (Arm), Carlos Vargas: 60 Day IL (Lat), J.P. Crawford: day-to-day (Undisclosed), Julio Rodríguez: day-to-day (Undisclosed)

Reds

Matt McLain: 10 Day IL (Calf), Blake Dunn: 10 Day IL (Elbow), Tony Santillan: 15 Day IL (Oblique), Nick Lodolo: 15 Day IL (Finger), Graham Ashcraft: 60 Day IL (Forearm), Brandon Williamson: 60 Day IL (Shoulder)

Stats to know
Seattle’s Randy Arozarena has hit 11 home runs this season. He has also tallied 45 RBIs and has scored 62 runs. In 401 plate appearances, he has recorded a .282 BA, .382 OBP and .446 SLG with a 10% walk rate and a 21.4% strikeout rate. He has been effective on the base paths, recording 19 steals on 24 attempts.
In 409 plate appearances, Josh Naylor has slashed .258/.321/.355 this season. He has hit eight long balls and driven in 37 runs with a strikeout rate of 12% and a walk rate of 7.6%. He has 20 stolen bases on 24 attempts. He has come around to score 37 times.
Cincinnati’s Sal Stewart is slashing .249/.328/.466 this season with 20 home runs, 70 RBIs (4th in MLB) and an OPS of .794. He has a 21.3% strikeout rate and a 10.6% walk rate in 436 plate appearances, and he has scored 52 total runs. Stewart has recorded 11 steals on 14 attempts.
In 362 plate appearances, Elly De La Cruz has hit 17 long balls, tallied 46 RBIs and scored 55 runs. He is batting .280/.354/.509 and has posted a 27.1% strikeout rate and a 9.9% walk rate. De La Cruz has recorded 15 steals on 21 attempts.

This watch guide was created using technology provided by Data Skrive.

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Photo: Jamie Squire, Ishika Samant, Scott Taetsch, Alika Jenner / Getty Images

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Jul 22, 2026

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