Animal Genetics and Genomics - United States News Beep

A repeat expansion in GOLGA8A is a major risk factor for atypical frontotemporal lobar degeneration with ubiquitin-positive inclusions

March 13, 2026

FTLD-FET consortium We established an international consortium to identify and bring together a sufficiently large case population to…

HHealth

Genome-wide association analyses highlight the role of the intestinal molecular environment in human gut microbiota variation

February 14, 2026

Ethical considerations The current study has been approved by the Swedish Ethical Review Authority (DNR 2022-06137-01, DNR 2024-01992-02).…

HHealth

Mutational scanning reveals oncogenic CTNNB1 mutations have diverse effects on signaling

February 3, 2026

CTNNB1 hotspot mutational patterns are tissue-specific We analyzed 9,248 tumors with CTNNB1 mutations in the COSMIC database (Fig.…

SScience

p53 inactivation drives breast cancer metastasis to the brain through SCD1 upregulation and increased fatty acid metabolism

December 29, 2025

Harbeck, N. et al. Breast cancer. Nat. Rev. Dis. Primers 5, 66 (2019). Article PubMed Google Scholar Chen,…

SScience

Adenine DNA methylation associated with transcriptionally permissive chromatin is widespread across eukaryotes

November 19, 2025

Iyer, L. M., Abhiman, S. & Aravind, L. Natural History of Eukaryotic DNA Methylation Systems, Vol. 101 (Elsevier,…

GGenetics

Pathogenic UNC13A variants cause a neurodevelopmental syndrome by impairing synaptic function

October 22, 2025

Institute of Medical Genetics, University of Zurich, Zurich, Switzerland Reza Asadollahi, Paranchai Boonsawat, Dennis Kraemer & Anita Rauch Faculty of Engineering and…

GGenetics

Natural selection exerted by historical coronavirus epidemic(s): comparative genetic analysis in China Kadoorie Biobank and UK Biobank | BMC Genomics

October 21, 2025

AppendixMethodsStatistics and reproducibility The details of each analysis are outlined in the methods section and all of the…

GGenetics

Modeling heterogeneity in single-cell perturbation states enhances detection of response eQTLs

October 21, 2025

Cohorts We used published data (GEO accession no. GSE162632) to study the effect of 12 h of ex vivo…

GGenetics

Genotyping sequence-resolved copy number variation using pangenomes reveals paralog-specific global diversity and expression divergence of duplicated genes

October 19, 2025

Overview of the genotyping method We represent variation as haplotype segments that are short enough to minimize disruption…

GGenetics

Redefining cellular reprogramming with advanced genomic technologies

October 18, 2025

Briggs, R. & King, T. J. Transplantation of living nuclei from blastula cells into enucleated Frogs’ eggs. Proc.…

GGenetics

Meta-analysis reveals differences in somatic alterations by genetic ancestry across common cancers

October 18, 2025

Genetic ancestry is a quantitative measure of inherited genetic variation and correlates with human migration patterns1. It contributes…

GGenetics

SPAmix: a scalable, accurate, and universal analysis framework for large-scale genetic association studies in admixed populations | Genome Biology

October 16, 2025

Model residuals of linear regression and logistic regression Linear regression and logistic regression are regular models to fit…