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Browsing Tag

Animal Genetics and Genomics

53 posts
GGenetics
SPAmix: a scalable, accurate, and universal analysis framework for large-scale genetic association studies in admixed populations | Genome Biology
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SPAmix: a scalable, accurate, and universal analysis framework for large-scale genetic association studies in admixed populations | Genome Biology

  • October 16, 2025
Model residuals of linear regression and logistic regression Linear regression and logistic regression are regular models to fit…
GGenetics
Genetic variation and genome-enabled selection of white lupin for key seed quality traits | BMC Genomics
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Genetic variation and genome-enabled selection of white lupin for key seed quality traits | BMC Genomics

  • October 16, 2025
Foyer CH, Lam H-M, Nguyen HT, Siddique KHM, Varshney RK, Colmer TD, et al. Neglecting legumes has compromised…
GGenetics
Population-scale gene-based analysis of whole-genome sequencing provides insights into metabolic health
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Population-scale gene-based analysis of whole-genome sequencing provides insights into metabolic health

  • October 11, 2025
Ethics Our research complies with all relevant ethical regulations. All studies included in this research were approved by…
GGenetics
Nucleotide dependency analysis of genomic language models detects functional elements
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Nucleotide dependency analysis of genomic language models detects functional elements

  • October 11, 2025
SpeciesLM training For SpeciesLM metazoa, we obtained metazoan genomes comprising 494 different species from the Ensembl 110 database36.…
GGenetics
A novel gene expression stability metric to unveil homeostasis and regulation | Genome Biology
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A novel gene expression stability metric to unveil homeostasis and regulation | Genome Biology

  • October 10, 2025
K-proportion and gene homeostasis Z-Index identify regulatory genes As cells of the same type and in the same…
GGenetics
Dissecting the impact of transcription factor dose on cell reprogramming heterogeneity using scTF-seq
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Dissecting the impact of transcription factor dose on cell reprogramming heterogeneity using scTF-seq

  • October 5, 2025
Constructing the scTF-seq library and single-cell atlas To establish scTF-seq, we built a dox-inducible lentiviral open reading frame…
GGenetics
A genetic map of human metabolism across the allele frequency spectrum
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A genetic map of human metabolism across the allele frequency spectrum

  • October 3, 2025
Study design The UKB is a prospective cohort study from the UK that contains more than 500,000 volunteers…
GGenetics
Exploring the genetic basis of heterosis in eucalypt growth based on transcriptome analysis | BMC Genomics
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Exploring the genetic basis of heterosis in eucalypt growth based on transcriptome analysis | BMC Genomics

  • October 3, 2025
Preparation of preliminary data In all samples, the proportion of clean reads was higher than 99.5% (Table S2),…
GGenetics
Mapping genes for resilient dairy cows by means of across-breed genome-wide association analysis | BMC Genomics
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Mapping genes for resilient dairy cows by means of across-breed genome-wide association analysis | BMC Genomics

  • October 1, 2025
Data processing and evaluation as well as statistical analyses were performed in software R 4.2.1 [16]. Genotype preparation,…
GGenetics
Limited overlap between genetic effects on disease susceptibility and disease survival
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Limited overlap between genetic effects on disease susceptibility and disease survival

  • September 30, 2025
Ethics statement This study was conducted in compliance with the relevant ethical guidelines and approved by the appropriate…
GGenetics
A clinical milestone for CRISPR in sickle-cell disease
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A clinical milestone for CRISPR in sickle-cell disease

  • September 28, 2025
The haemoglobinopathies transfusion-dependent β-thalassemia (TDT) and sickle-cell disease (SCD) are two globally prevalent and severe monogenic blood disorders.…
GGenetics
Advances in haplotype phasing and genotype imputation
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Advances in haplotype phasing and genotype imputation

  • September 24, 2025
Voight, B. F., Kudaravalli, S., Wen, X. & Pritchard, J. K. A map of recent positive selection in…
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