CRISPR–Cas regulates expression of embedded anti-phage defence systems
Hampton, H. G., Watson, B. N. J. & Fineran, P. C. The arms race between bacteria and their…
A phage puts a new spin on bacterial flagella
Transposon-encoded TnpB proteins are RNA-guided nucleases that use a transposon-encoded guide RNA to cleave DNA target sequences, promoting…
Temperate phages enhance bacterial host fitness via RNA-guided flagellar remodelling
Mata, J., Marguerat, S. & Bähler, J. Post-transcriptional control of gene expression: a genome-wide perspective. Trends Biochem. Sci.…
Bridging continuous and discrete evolution through a controllable, hypermutagenic phage-bacteria system
General methods All E. coli and phage strains created in this study are listed in Supplementary Table 1,…
Translation-dependent degradation of cas12 mRNA triggered by an anti-CRISPR
Murtazalieva, K., Mu, A., Petrovskaya, A. & Finn, R. D. The growing repertoire of phage anti-defence systems. Trends…
Nuclease–NTPase antiphage defence systems use conserved molecular features to control bacterial immunity
Roberts, R. J. et al. A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes. Nucleic…
Scientists Just Watched These Entities Rapidly Evolve In Space. They Could Save Our Lives.
Here’s what you’ll learn when you read this story: As bacteria become increasingly (and worryingly) resistant to antibiotics,…
‘Dragon Hole’: Scientists found a huge ocean sinkhole hiding 1,700 strange viruses beneath the sea |
Deep in the South China Sea, scientists from Chinese marine research institutes, including the First Institute of Oceanography,…
Isolation, engineering and ecology of temperate phages from the human gut
Camarillo-Guerrero, L. F., Almeida, A., Rangel-Pineros, G., Finn, R. D. & Lawley, T. D. Massive expansion of human…