A novel gene expression stability metric to unveil homeostasis and regulation | Genome Biology
K-proportion and gene homeostasis Z-Index identify regulatory genes As cells of the same type and in the same…
‘Google for DNA’ brings order to biology’s big data
MetaGraph indexes and vast archives of DNA, RNA, and protein sequences. Scientists can search the archives and trace…
Dissecting the impact of transcription factor dose on cell reprogramming heterogeneity using scTF-seq
Constructing the scTF-seq library and single-cell atlas To establish scTF-seq, we built a dox-inducible lentiviral open reading frame…
Advances in haplotype phasing and genotype imputation
Voight, B. F., Kudaravalli, S., Wen, X. & Pritchard, J. K. A map of recent positive selection in…
Further phenotypical delineation of DLG3-related neurodevelopmental disorders
Elias GM, Elias LAB, Apostolides PF, Kriegstein AR, Nicoll RA. Differential trafficking of AMPA and NMDA receptors by…
MSnLib: efficient generation of open multi-stage fragmentation mass spectral libraries
Materials All solvents used were of LC–MS grade. Methanol, acetonitrile, water and formic acid were obtained from Thermo…
Clinical exome sequencing efficacy and phenotypic expansions involving non-isolated congenital anomalies of kidney and urinary tract (CAKUT+)
Capone VP, Morello W, Taroni F, Montini G. Genetics of congenital anomalies of the kidney and urinary tract:…
Gilgo Beach serial killer case a key test in use of advanced DNA techniques in criminal trials | National News
RIVERHEAD, N.Y. (AP) — When Maureen Brainard-Barnes’ skeletal remains were found hidden in the roadside scrub near Long…
Bearded Dragons Can Switch Sex. Scientists Finally Found Out How
Bearded dragons are famous for their ability to change sex depending on heat and genes. Two new genome…
Prenatal Variants of Uncertain Significance (VUS): to report or not to report?
Lord J, McMullan DJ, Eberhardt RY, Rinck G, Hamilton SJ, Quinlan-Jones E, et al. Prenatal exome sequencing analysis…
GeneRiskCalc: a web-based tool for genetic risk association analysis in case–control studies | BMC Bioinformatics
Hardy–Weinberg equilibrium The HWE is a key principle in population genetics, stating that allele and genotype frequencies remain…
Neurobehavioral profile of individuals with pathogenic variants in CHD3
Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195…