How do genetic association studies rank genes?
RESEARCH BRIEFINGS 19 November 2025 Genome-wide association studies and rare-variant burden tests are the two main tools for…
MSnLib: efficient generation of open multi-stage fragmentation mass spectral libraries
Materials All solvents used were of LC–MS grade. Methanol, acetonitrile, water and formic acid were obtained from Thermo…
CRISPR screening by AAV episome-sequencing (CrAAVe-seq): a scalable cell-type-specific in vivo platform uncovers neuronal essential genes
Animals All mice were maintained according to the National Institutes of Health guidelines and all procedures used in…
Genetic findings of children with congenital heart diseases using chromosomal microarray and trio-based whole exome sequencing
We utilized chromosomal microarray analysis (CMA) and whole exome sequencing (WES) to investigate the prevalence of clinically relevant…