Ketogenic diet mediates intestinal tumorigenesis through lipids not ketones
Shay, J. E. S. & Yilmaz, ÖH. Dietary and metabolic effects on intestinal stem cells in health and…
Steatosis shapes prognosis-defining liver metastasis heterogeneity in CRC
Kow, A. W. C. Hepatic metastasis from colorectal cancer. J. Gastrointest. Oncol. 10, 1274–1298 (2019). Article PubMed PubMed…
Cancer cells have an Achilles heel, they can be starved to death
Quick summary – click for full details Concise summary of key highlights In one line Unlike normal cells,…
Ageing promotes metastasis via activation of the integrated stress response
Mice and in vivo studies KrasLSL-G12D/+Trp53flox/flox mice (designated as KP)60 were maintained on a mixed C57BL/6-129/Sv genetic background.…
Cytosolic acetyl-coenzyme A is a signalling metabolite to control mitophagy
Mouse studies Wild-type C57BL/6 male mice (6–8 weeks of age) were purchased from BIKAI. Nlrx1−/− mice were purchased from Cyagen.…
Lymph node environment drives FSP1 targetability in metastasizing melanoma
Cell lines B16-F0 (ATCC; CRL-6322) and its LN metastatic derivatives: NBF0-LN1-18IL, NBF0-LN7-1112AR, NBF0-LN7-1120BL, NBF0-LN7-1134BL, NBF0-LN8-1194BR, NBF0-LN8-1198AR, NBF0-LN8-1205BL, NBF0-LN9-1315BL…
Fructose and glucose from sugary drinks enhance colorectal cancer metastasis via SORD
Cell culture and cell lines The following CRC cell lines were obtained from the American Type Culture Collection…