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Browsing Tag

Cancer Research

60 posts
GGenetics
Chromatin dynamics of a large-sized genome provides insights into polyphenism and X0 dosage compensation of locusts
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Chromatin dynamics of a large-sized genome provides insights into polyphenism and X0 dosage compensation of locusts

  • September 1, 2025
Chromosome-level assembly of the migratory locust We conducted genome sequencing on an adult female locust with a heterozygosity…
GGenetics
Cross-biobank generalizability and accuracy of electronic health record-based predictors compared to polygenic scores
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Cross-biobank generalizability and accuracy of electronic health record-based predictors compared to polygenic scores

  • August 27, 2025
Ethics declarations Patients and control participants in FinnGen provided informed consent for biobank research, based on the Finnish…
GGenetics
Precise modulation of BRG1 levels reveals features of mSWI/SNF dosage sensitivity
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Precise modulation of BRG1 levels reveals features of mSWI/SNF dosage sensitivity

  • August 22, 2025
BRG1 binding exhibits a linear response to its dosage In mES cells, Brg1 encodes the major catalytic subunit…
GGenetics
Tamoxifen induces PI3K activation in uterine cancer
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Tamoxifen induces PI3K activation in uterine cancer

  • August 22, 2025
Ethics statement This study complies with all relevant ethical regulations. TAMARISK specimens were obtained and sequenced with the…
GGenetics
KidneyGenAfrica, a pan-African partnership to deliver research and training excellence in genomics of kidney disease
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KidneyGenAfrica, a pan-African partnership to deliver research and training excellence in genomics of kidney disease

  • August 20, 2025
Precision Healthcare University Research Institute, Queen Mary University of London, London, UK Segun Fatumo, Oyesola Ojewunmi, Rebecca Camenzuli, Christopher Kintu & Claudia Langenberg…
HHealth
Tracing the evolution of single-cell 3D genomes in Kras-driven cancers
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Tracing the evolution of single-cell 3D genomes in Kras-driven cancers

  • August 19, 2025
Ethics Statement All animal studies were approved by the Institutional Animal Care and Use Committee of Yale University.…
GGenetics
Graves Gilbert Clinic discusses advancements in breast cancer research for Breast Cancer Research Day
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Graves Gilbert Clinic discusses advancements in breast cancer research for Breast Cancer Research Day

  • August 19, 2025
BOWLING GREEN, Ky. – Today is World Breast Cancer Research Day, and across the country, thousands of women…
GGenetics
Large-scale genome-wide analyses of stuttering
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Large-scale genome-wide analyses of stuttering

  • August 17, 2025
Yairi, E. & Ambrose, N. Epidemiology of stuttering: 21st century advances. J. Fluen. Disord. 38, 66–87 (2013). Google…
SScience
From gene hunter to drug hunter
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From gene hunter to drug hunter

  • August 15, 2025
Howard Chang wasn’t looking for a change from his job at Stanford, where he worked as both a…
HHealth care
A Society-to-Cells approach to evaluating multilevel and interrelated drivers of breast cancer disparities in Black women
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A Society-to-Cells approach to evaluating multilevel and interrelated drivers of breast cancer disparities in Black women

  • August 13, 2025
Miller, K. D. et al. Cancer treatment and survivorship statistics, 2019. CA Cancer J. Clin. 69, 363–385 (2019).…
GGenetics
LDAK-KVIK performs fast and powerful mixed-model association analysis of quantitative and binary phenotypes
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LDAK-KVIK performs fast and powerful mixed-model association analysis of quantitative and binary phenotypes

  • August 12, 2025
Uffelmann, E. et al. Genome-wide association studies. Nat. Rev. Methods Prim. 1, 59 (2021). CAS  Google Scholar  Visscher,…
GGenetics
Comprehensive transcription factor perturbations recapitulate fibroblast transcriptional states
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Comprehensive transcription factor perturbations recapitulate fibroblast transcriptional states

  • August 11, 2025
Regev, A. et al. The human cell atlas. eLife 6, e27041 (2017). PubMed  PubMed Central  Google Scholar  Karlsson,…
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