Can a groundbreaking cancer therapy help people with multiple sclerosis?
Grace Miller at a follow-up visit at the Cleveland Clinic nine months after she underwent an experimental CAR-T…
SLAMF6 as a drug-targetable suppressor of T cell immunity against cancer
Sharma, P. & Allison, J. P. Dissecting the mechanisms of immune checkpoint therapy. Nat. Rev. Immunol. 20, 75–76…
Tracking clonal evolution during treatment in ovarian cancer using cell-free DNA
Sample collection All enrolled patients were consented to an institutional biospecimen banking protocol and MSK-IMPACT testing42, and all…
Temporal control of human DNA replication licensing by CDK4/6-RB signalling and chemical genetics
Turning off origin licensing within one cell cycle We have previously developed protein depletion technologies to suppress initiation…