Systemic epigenetic dysregulation as a driver of ageing and a therapeutic target
Guo, J. et al. Aging and aging-related diseases: from molecular mechanisms to interventions and treatments. Signal. Transduct. Target.…
Cell-free chromatin state tracing reveals disease origin and therapy responses
Patients The research presented in this study complies with all the relevant ethical regulations at their respective centres.…
Research sheds new light on depression’s biological roots
Researchers at McGill University and the Douglas Institute have identified two specific types of brain cells that are…
Next-gen sequencing reveals the regulatory potential of the non-coding genome
The non-coding genome, once dismissed as “junk DNA”, is now recognized as a fundamental regulator of gene expression…
Scientists reveal how rare gene mutations drive schizophrenia risk
Uncovering how rare genetic changes disrupt brain signaling and structure, this landmark study sheds new light on the…