How to build a mouse: embryo development captured in stunning detail
By introducing and tracking mutations as the cells of a mouse embryo divide, researchers have mapped relationship between…
Human brain cells transplanted into mice in ‘most extensive’ integration ever
Human brain tissue transplanted into mice that lack a key part of their brains can grow to occupy…
Developmental xenocortication using human-derived organoids in mice
Genetically encoded cortical depletion Emx1-cre (JAX, B6.129S2-Emx1tm1(cre)Krj/J), Esco2fl/fl (JAX, B6N.129S-Esco2tm1.1Ge/J) and C57BL SCID (JAX, B6.Cg-Prkdcscid/SzJ) mice were used…
Early Exercise May Permanently Change How Much Energy the Body Uses To Move
Physical demands during growth may leave a lasting mark on how efficiently the body moves. In an experiment…
Lab-grown sperm: scientists inch closer to fertility breakthrough
Researchers are trying to make human sperm (shown here in a colourized electron microscope image) from stem cells…
Scientists Discover a Gene That Boosts Youth – but It Comes With a Cost
Researchers found that vgll3 boosts early-life growth and reproduction but increases aging and cancer risk later, providing strong…
Cell transplant across the tree of life hints at how animals emerged
Researchers transplanted cells between embryos of a comb jelly (Mnemiopsis leidyi, right) and a starlet sea anemone (Nematostella…
Cannibal ‘supergiant’ microbe found hunting and devouring members of own species
Scientists have documented for the first time a microbe that drastically transforms its size, shape, and behaviour into…
Space embryos: China launches lab-grown human cells into orbit to study reproduction
China has sent artificially constructed human embryo models to the Tiangong space station, marking the first known attempt…
how X affects your health
Cholesterol-lowering statins are among the most widely prescribed drugs in the world. They can have side effects, however,…
Single-cell spatiotemporal dissection of the human maternal–fetal interface
Tissue acquisition and processing for joint single-nucleus multiome profiling and spatial transcriptomics Snap-frozen decidual and basal plate samples…
Systemic epigenetic dysregulation as a driver of ageing and a therapeutic target
Guo, J. et al. Aging and aging-related diseases: from molecular mechanisms to interventions and treatments. Signal. Transduct. Target.…