New generation of CRISPR shows safer path to treating genetic diseases
A new generation of CRISPR technology developed at UNSW Sydney offers a safer path to treating genetic diseases…
Study: Genetic Variant Inherited from Neanderthals Reduces Activity of Key Muscle Enzyme
The Neanderthal variant in AMPD1 decreases its enzymatic activity by 25% in lab-produced proteins and by up to…
Scientists Decode Genome of Sweetpotato
Researchers have produced a chromosome-level genome assembly for a sweetpotato cultivar called ‘Tanzania.’ ‘Tanzania’ sweetpotato variety. Image credit:…
Decoding macrophage immune responses with gene editing and machine learning
Fighting off pathogens is a tour de force that must happen with speed and precision. A team of…
Exploring the genetic and clinical landscape of clubfoot
A new publication offers an extensive examination of clubfoot, a congenital deformity known as congenital talipes equinovarus (CTEV),…
Genetic testing can guide safer chemotherapy for gastrointestinal cancer patients
For some patients with gastrointestinal (GI) cancers like colorectal and pancreatic cancer, chemotherapy can cause severe, sometimes life-threatening…
Prime editing reverses symptoms of severe childhood neurological disease
Scientists use a precise form of gene editing called prime editing to correct the most common genetic mutations…
Scientists reveal how rare gene mutations drive schizophrenia risk
Uncovering how rare genetic changes disrupt brain signaling and structure, this landmark study sheds new light on the…
$5.5 million federal grant funds research to improve measurement of FXTAS treatments
UC Davis Health Professor of Psychiatry and Behavioral Sciences David Hessl will help lead a major research project…
Researchers classify how specific genetic mutations correspond to rare disorders
The NF-κB signaling pathway plays a pivotal role in how our bodies fight infection, heal, and regulate inflammation.…
New research identifies critical gene for treatment
Amyotrophic lateral sclerosis (ALS) – which you may know as the disease that affected Stephen Hawking – is…
Researchers pinpoint PRMT5 as a promising target for cancer drugs
A potential target for experimental drugs that block PRMT5 – a naturally occurring enzyme some tumors rely more…