Fresh claim of making elusive ‘hexagonal’ diamond is the strongest yet
Conventional diamond, called cubic diamond, is known as the hardest substance in the world. But researchers think hexagonal…
DICER cleavage fidelity is governed by 5′-end binding pockets
Plasmid construction The pXG-10×His-DICER plasmid was generated by inserting a DNA sequence encoding human DICER (amino acids 25–1922)…
Do obesity drugs treat addiction? Huge study hints at their promise
Injections that reduce weight and treat diabetes could also cut the risk of dying from substance-use disorders.Credit: Jill…
The molecular basis of force selectivity by PIEZO2
Study design No statistical methods were used to predetermine sample size and the sample size was based on…
The oldest articulated bony fish from the early Silurian period
Brazeau, M. D. & Friedman, M. The origin and early phylogenetic history of jawed vertebrates. Nature 520, 490–497…
Long-term thrombus-free left atrial appendage occlusion via magnetofluids
Alkhouli, M. et al. Left atrial appendage occlusion: current advances and remaining challenges. JACC Adv. 1, 100136 (2022).…
A glucocorticoid–FAS axis controls immune evasion during metastatic seeding
Lambert, A. W., Zhang, Y. & Weinberg, R. A. Cell-intrinsic and microenvironmental determinants of metastatic colonization. Nat. Cell…
Cell-free chromatin state tracing reveals disease origin and therapy responses
Patients The research presented in this study complies with all the relevant ethical regulations at their respective centres.…
Limited thermal tolerance in tropical insects and its genomic signature
Study area In Peru, the study was carried out along an elevational gradient from 245 masl to the tree…
Lipid metabolism drives dietary effects on T cell ferroptosis and immunity
Matsushita, M. et al. T cell lipid peroxidation induces ferroptosis and prevents immunity to infection. J. Exp. Med.…
Microbiota-mediated induction of beige adipocytes in response to dietary cues
Mice SPF C57BL/6 (B6), BALB/c and ICR mice were purchased from Japan SLC, CLEA Japan and the Jackson…
Homologous recombination deficiency and hemizygosity drive resistance in breast cancer
Study cohort and prospective sequencing The study cohort comprised 6,927 tumour samples from 5,881 patients with breast cancer.…