Engineered prime editors with minimal genomic errors
Mammalian cell culture All mammalian cell cultures were maintained in a 37 °C incubator at 5% CO2. HEK293T human…
Delegation to artificial intelligence can increase dishonest behaviour
Recruitment of human participants In all studies involving human participants, we recruited participants from Prolific. We sought samples…
High-density soft bioelectronic fibres for multimodal sensing and stimulation
Canales, A., Park, S., Kilias, A. & Anikeeva, P. Multifunctional fibers as tools for neuroscience and neuroengineering. Acc.…
Atomic-scale imaging of frequency-dependent phonon anisotropy
Schubert, M. et al. Anisotropy, phonon modes, and free charge carrier parameters in monoclinic β-gallium oxide single crystals.…
A domed pachycephalosaur from the early Cretaceous of Mongolia
Sues, H.-D. Functional morphology of the dome in pachycephalosaurid dinosaurs. N. Jb. Geol. Palaontol. Mh. 8, 459–472 (1978).…
AI is helping to decode animals’ speech. Will it also let us talk with them?
Deep in the rainforests of the Democratic Republic of the Congo, Mélissa Berthet found bonobos doing something thought…
Analytical construction and visualization of nonlinear waves in the (2+1) dimensional Kadomtsev-Petviashvili-Sawada-Kotera-Ramani equation with stability analysis
The steps of the improved modified extended Tanh method that were explained in the preceding section will be…
How should ‘mirror life’ research be restricted? Debate heats up
Some researchers are developing biological systems that create mirror-image versions of DNA and other molecules crucial to life.Credit:…
how to fight back against a peer-review bully
Nyssa Silbiger still recalls the rude remark that reviewer three made in 2014 about her first paper describing…
black-hole breakthroughs will ‘only get better’
The Laser Interferometer Gravitational-wave Observatory (LIGO) facility, in Hanford, Washington.Credit: IMAGO/Xinhua via Alamy Ten years after the historic…
Temporal control of human DNA replication licensing by CDK4/6-RB signalling and chemical genetics
Turning off origin licensing within one cell cycle We have previously developed protein depletion technologies to suppress initiation…
RFK Jr’s vaccine advisers will soon review four shots: what’s at stake
A child receives a measles, mumps and rubella vaccine earlier this year in Lubbock, Texas.Credit: Jan Sonnenmair/Getty Next…