CRISPR gets a power boost from AI-designed ‘molecular scissors’
An enzyme cuts DNA (artist’s impression). Synthetic protein-cleaving enzymes were designed quickly with the help of artificial intelligence.Credit:…
Delayed molecular aging, preservation of energy metabolism and enhanced exercise response in exercise-trained human muscle
López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M. & Kroemer, G. The hallmarks of aging. Cell 153,…
A Surprising Discovery Challenges What Scientists Thought DNA Methylation Was For
A study of sea anemones uncovers an ancient role for DNA methylation and shows that certain epigenetic changes…
These ‘master’ proteins protect us from deadly mutations — and could inspire new drugs
Our genomes are full of mutations that have the potential to damage our health or even kill us.…
New Discovery Reveals Vitamin K’s Surprising Role in Preventing Bone Loss
Bone is constantly renewed through a delicate balance between cells that build bone and cells that break it…
Mitochondria directly interact with the nuclear pore complex
Copeland, D. E. & Dalton, A. J. An association between mitochondria and the endoplasmic reticulum in cells of…
New Discovery Challenges Decades-Old Theory of DNA Damage and Aging
Researchers have identified an overactive immune response as a major contributor to tissue degeneration in severe DNA repair…
Powerful Antioxidant Found To Play a Key Role in Proper Protein Folding
The ER is shown in the upper right, with disulfide-linked GSSG in the lumen. The exporter resembles the…
All life runs on 20 amino acids. These cells run key machinery on just 19
Scientists equipped Escherichia coli (example pictured) with ribosomes that lacked the amino acid isoleucine.Credit: James Cavallini/Science Photo Library…
Scientists Discover Natural Molecule That Stops Alzheimer’s Protein Clumps From Forming
Scientists have uncovered evidence that the formation of functional protein droplets and harmful fibrils can be separated. By…
eating primes immune cells for action
T cells, shown here attacking a tumour cell, might provide a better defence after a person has eaten.Credit:…
Bread Might Be Making You Gain Weight Even Without Eating More Calories
In a new study, mice strongly preferred foods like bread, rice, and wheat, abandoning their regular diet and…