This super-cold microscope could spur a quantum revolution
GAIA is a scanning transmission electron microscope with a built-in system to cool samples to ultra-low temperatures with…
All the ways a cell can die — and why the variety matters
The cells in Daolin Tang’s Petri dishes were dead. Signs of life had dropped off a cliff; they…
Drug firms’ secret data supercharge AI protein models
Artificial-intelligence-based models of protein structure could be improved by incorporating data from pharmaceutical companies.Credit: Miyako Nakamura/Getty For drug…
CRISPR gets a power boost from AI-designed ‘molecular scissors’
An enzyme cuts DNA (artist’s impression). Synthetic protein-cleaving enzymes were designed quickly with the help of artificial intelligence.Credit:…
Delayed molecular aging, preservation of energy metabolism and enhanced exercise response in exercise-trained human muscle
López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M. & Kroemer, G. The hallmarks of aging. Cell 153,…
A Surprising Discovery Challenges What Scientists Thought DNA Methylation Was For
A study of sea anemones uncovers an ancient role for DNA methylation and shows that certain epigenetic changes…
These ‘master’ proteins protect us from deadly mutations — and could inspire new drugs
Our genomes are full of mutations that have the potential to damage our health or even kill us.…
New Discovery Reveals Vitamin K’s Surprising Role in Preventing Bone Loss
Bone is constantly renewed through a delicate balance between cells that build bone and cells that break it…
Mitochondria directly interact with the nuclear pore complex
Copeland, D. E. & Dalton, A. J. An association between mitochondria and the endoplasmic reticulum in cells of…
New Discovery Challenges Decades-Old Theory of DNA Damage and Aging
Researchers have identified an overactive immune response as a major contributor to tissue degeneration in severe DNA repair…
Powerful Antioxidant Found To Play a Key Role in Proper Protein Folding
The ER is shown in the upper right, with disulfide-linked GSSG in the lumen. The exporter resembles the…
All life runs on 20 amino acids. These cells run key machinery on just 19
Scientists equipped Escherichia coli (example pictured) with ribosomes that lacked the amino acid isoleucine.Credit: James Cavallini/Science Photo Library…