New gene-editing method can correct many disease-causing mutations in mammalian cells
Some genetic disorders-such as cystic fibrosis, hemophilia and Tay Sachs disease-involve many mutations in a person’s genome, often…
Orange Cats Are Genetically Unlike Any Other Mammal and Now We Know Why
Credit: Pixabay. Chris Kaelin, a geneticist at Stanford Medicine, found himself thinking about cats. Not just any cats,…
Pioneering personalized medicine by deciphering depression’s complex biological web
In a compelling Genomic Press Interview published today in Genomic Psychiatry, Dr. Najaf Amin unveils transformative insights that…
Hotspots of human mutation point to clonal expansions in spermatogonia
Lawson, A. R. J. et al. Somatic mutation and selection at population scale. Nature https://doi.org/10.1038/s41586-025-09584-w (2025). Maeda, H.…
Somatic mutation and selection at population scale
Cohort selection The TwinsUK study contains around 16,000 participants. From a preselection of 4,800 donors, we invited 1,796…
“Junk DNA” Provides Surprising New Treatments for Hard-To-Treat Blood Cancers
Researchers at King’s College London have uncovered a surprising vulnerability in certain blood cancers by targeting a part…
Low dose of aspirin cuts recurrence risk in colorectal cancer with genetic mutation
A Swedish-led research team at Karolinska Institutet and Karolinska University Hospital has shown in a new randomized clinical…
Genetic mutation in some East Asians linked to aldehyde storm and increased liver disease risk
Researchers have identified the mechanism by which a common genetic mutation increases liver disease risk. Their findings suggest…
Zebrafish study reveals how environment influences social behaviors in autism
Researchers from Brain Research Institute, Niigata University, Japan have revealed that environment influences social behaviors in autism. By…
A novel MCMDC2 variant causes meiotic arrest and non-obstructive azoospermia in a consanguineous Chinese family
Cerván-Martín M, Castilla JA, Palomino-Morales RJ, Carmona FD. Genetic landscape of nonobstructive azoospermia and new perspectives for the…
Insights into clinical features and genetic variants of Cornelia de Lange syndrome in China
Cornelia de Lange syndrome (CdLS) is a rare genetic disorder with symptoms, including facial anomalies (such as fused…
Prime editing reverses symptoms of severe childhood neurological disease
Scientists use a precise form of gene editing called prime editing to correct the most common genetic mutations…