Hotspots of human mutation point to clonal expansions in spermatogonia
Lawson, A. R. J. et al. Somatic mutation and selection at population scale. Nature https://doi.org/10.1038/s41586-025-09584-w (2025). Maeda, H.…
Sperm sequencing reveals extensive positive selection in the male germline
Ethics This study was carried out under TwinsUK BioBank ethics, approved by the North West–Liverpool Central Research Ethics…
Whole-genome sequencing of 490,640 UK Biobank participants
We integrated deep phenotyping data27 available for most UKB participants and performed genetic association analysis across selected disease…