Structural basis of supercoiling-induced CRISPR–Cas9 off-target activity
Pacesa, M., Pelea, O. & Jinek, M. Past, present, and future of CRISPR genome editing technologies. Cell 187,…
The molecular basis of force selectivity by PIEZO2
Study design No statistical methods were used to predetermine sample size and the sample size was based on…
Quantitative evaluation of methods to analyze motion changes in single-particle experiments
Datasets and ground truth In order to benchmark the different methods on data with a known ground truth,…
Elastic properties of force-transmitting linkages determine multistable mechanosensitive behaviour of cell adhesion
Semi-analytical mechanical model of cell-adhesion complexes To study the potential effect of the elastic properties of molecular clutches…