Naked Mole-Rats’ Long Life Due to Better DNA Repair Mechanisms
Naked mole-rats are well known for both their wrinkly appearance and for their unexpectedly long lives. The source…
Wheat Pan-Transcriptome Reveals Functional Diversity to Transform Global Breeding Efforts
Wheat is the most widely cultivated crop in the world; over 215 million hectares are grown annually. To…
Generative AI Designs Synthetic Gene Editing Proteins Better than Nature
Credit: vchal/Getty Images Researchers from Integra Therapeutics, in partnership with the Pompeu Fabra University (UPF) and the Center…
Alnylam Joins Illumina and NashBio for Faster, More Inclusive Drug Discovery
Credit: Andrew Brookes / Connect Images When Alnylam Pharmaceuticals announced it would join the Alliance for Genomic Discovery…
Pan-Cancer Immunotherapy Avoids Healthy Tissue by Targeting Glycans
Bispecific antibodies and chimeric antigen receptor (CAR) T cells demonstrate potent cancer immunotherapy in clinical use, yet most…
Pan-Cancer Immunotherapy Avoids Healthy Tissue by Targeting Glycans
Bispecific antibodies and chimeric antigen receptor (CAR) T cells demonstrate potent cancer immunotherapy in clinical use, yet most…
Bridge Recombinase Platform Enables Megabase-Scale Human Genome Rearrangements
For decades, gene-editing science has been limited to making small, precise edits to human DNA, akin to correcting…
Experimental Neuroblastoma Therapy Overcomes Resistance in Mice
Credit: Nemes Laszlo/Getty Images Researchers at St. Jude Children’s Research Hospital have reported encouraging results for a novel…
Genome Assembly of Human Epithelial Cell Line Completed at Reference Quality
In a new study published in Nature Communications titled, “The reference genome of the human diploid cell line…
AI Model Finds Gene Targets and Drug Combos to Reprogram Diseased Cells
Credit: FlashMovie/Getty Images Traditional drug discovery has often followed the “one drug, one target” paradigm—developing compounds against individual…
Autoimmune Disease Risk Linked to mRNA Instability
Credit: Christoph Burgstedt / Getty Images / Science Photo Library Researchers at the University of California Los Angeles…
CRISPR Screen Identifies GATOR1 as Lymphoma Tumor Suppressor
Credit: CoRus13 via Wikimedia Commons A team of Australian researchers has identified a set of genes that encode…