Alnylam Joins Illumina and NashBio for Faster, More Inclusive Drug Discovery
Credit: Andrew Brookes / Connect Images When Alnylam Pharmaceuticals announced it would join the Alliance for Genomic Discovery…
Pan-Cancer Immunotherapy Avoids Healthy Tissue by Targeting Glycans
Bispecific antibodies and chimeric antigen receptor (CAR) T cells demonstrate potent cancer immunotherapy in clinical use, yet most…
Pan-Cancer Immunotherapy Avoids Healthy Tissue by Targeting Glycans
Bispecific antibodies and chimeric antigen receptor (CAR) T cells demonstrate potent cancer immunotherapy in clinical use, yet most…
Bridge Recombinase Platform Enables Megabase-Scale Human Genome Rearrangements
For decades, gene-editing science has been limited to making small, precise edits to human DNA, akin to correcting…
Experimental Neuroblastoma Therapy Overcomes Resistance in Mice
Credit: Nemes Laszlo/Getty Images Researchers at St. Jude Children’s Research Hospital have reported encouraging results for a novel…
Genome Assembly of Human Epithelial Cell Line Completed at Reference Quality
In a new study published in Nature Communications titled, “The reference genome of the human diploid cell line…
AI Model Finds Gene Targets and Drug Combos to Reprogram Diseased Cells
Credit: FlashMovie/Getty Images Traditional drug discovery has often followed the “one drug, one target” paradigm—developing compounds against individual…
Autoimmune Disease Risk Linked to mRNA Instability
Credit: Christoph Burgstedt / Getty Images / Science Photo Library Researchers at the University of California Los Angeles…
CRISPR Screen Identifies GATOR1 as Lymphoma Tumor Suppressor
Credit: CoRus13 via Wikimedia Commons A team of Australian researchers has identified a set of genes that encode…
Single-Cell Proteomics Reveal Hidden Layers of Gene Expression
Single cell gene expression studies often rely on single-cell RNA sequencing (scRNA-seq) alone. While scRNA-seq reveals which genes…
Organoids Used to Find New Alzheimer’s Disease Treatment Target
Credit: Kateryna Kon/ Getty Images / Science Photo Library Researchers at ShanghaiTech University in China have discovered a…
Sarepta Says Deaths of Two Elevidys Patients Posted on FDA Database Unrelated to Treatment
Sarepta Therapeutics (NASDAQ: SRPT) said Friday that the deaths of two patients taking its marketed gene therapy Elevidys®…