{"id":214132,"date":"2025-10-10T11:20:29","date_gmt":"2025-10-10T11:20:29","guid":{"rendered":"https:\/\/www.newsbeep.com\/us\/214132\/"},"modified":"2025-10-10T11:20:29","modified_gmt":"2025-10-10T11:20:29","slug":"longevity-influencers-love-this-mitochondria-makeover-pill-for-energy-and-strength","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us\/214132\/","title":{"rendered":"Longevity influencers love this &#8216;mitochondria makeover pill&#8217; for energy and strength"},"content":{"rendered":"<p>Urolithin A has been called the \u201cmitochondria makeover pill,\u201d a powerful fuel to trigger cellular regeneration that makes people feel younger.<\/p>\n<p>Naturally, boasting such a claim may invite skepticism \u2014 but longevity influencers swear by it, making  it one of the hot new trends in the booming anti-aging industry.<\/p>\n<p>So what can taking this buzzy supplement actually do for you \u2014 and is it worth it?<\/p>\n<p>Urolithin A, dubbed the \u201cmitochondria makeover pill,\u201d has sparked debate over whether it\u2019s a breakthrough or just hype. Luca \u2013 stock.adobe.com<\/p>\n<p>What is Urolithin A and where does it come from?<\/p>\n<p>Urolithin A is a type of postbiotic. Unlike probiotics \u2014 which are found directly in foods like yogurt and sauerkraut \u2014 postbiotics are what\u2019s leftover after your body digests food, a waste left behind by our gut bacteria.<\/p>\n<p>Both probiotics and postbiotics help contribute to having a <a href=\"https:\/\/nypost.com\/2024\/10\/04\/health\/improve-gut-health-with-probiotics-prebiotics-fibrous-foods-water-doctor\/\" rel=\"nofollow noopener\" target=\"_blank\">healthy gut microbiome<\/a>, which can influence not just your digestion and nutrition absorption but also your immune system, sleep and risk of chronic diseases.<\/p>\n<p>Urolithin A, in particular, is made when we eat pomegranates, walnuts or berries. But only about 40% of people can produce it efficiently. Supplements aim to bridge that gap.<\/p>\n<p>What does Urolithin A do?<\/p>\n<p>\u201cUrolithin A supports mitophagy, the cellular process of clearing damaged mitochondria so healthier ones can thrive,\u201d Jenelle Kim, founder of JBK Wellness Labs, told The Post.<\/p>\n<p>\u201cThis means better energy at the cellular level, stronger muscles and overall healthier cells.\u201d <\/p>\n<p>On dosing, Kim noted that clinical studies typically use between 500\u20131,000 mg per day, taken consistently \u2014 often as a capsule with food.<\/p>\n<p>Dr. Gabrielle Lyon says Urolithin A \u201cimproves mitochondrial biogenesis and reduces inflammatory signaling.\u201d Instagram\/drgabriellelyon<\/p>\n<p>What are the benefits of Urolithin A?<\/p>\n<p>In studies of older adults, Urolithin A improved leg\/hand muscle endurance. It also boosted muscle strength, exercise performance and mito-health biomarkers in a trial of middle-aged adults.<\/p>\n<p>Young adults who lead an athletic lifestyle can expect enhanced recovery after exercise, according to Dr. Gabrielle Lyon, founder of the Muscle-Centric Medicine movement.<\/p>\n<p>\u201cPeople often report steadier sustained energy and lower fatigue [and] exertion levels,\u201d she said.<\/p>\n<p>Reddit users have credited Urolithin A with helping them \u201cbounce back faster from workouts,\u201d \u201cfeel less sore\u201d and \u201cget through the day without the usual afternoon crash.\u201d<\/p>\n<p>Clinical studies show Urolithin A can improve muscle strength and endurance, especially in middle-aged adults. andyleaw \u2013 stock.adobe.com<\/p>\n<p>Lyon also cited unpublished human studies that suggest Urolithin A could play a role in reducing \u201cinflammaging\u201d while boosting immune fitness. <\/p>\n<p>She pointed to trials of topical application that show improvements in skin aging factors, including collagen assembly, UVB exposure recovery, firmness and reduction in fine lines.<\/p>\n<p>Research <a href=\"https:\/\/nypost.com\/2024\/06\/07\/health\/alzheimers-patients-could-help-alleviate-symptoms-by-eating-this-food-study\/\" rel=\"nofollow noopener\" target=\"_blank\">published last year<\/a> found that it might even \u201calleviate memory problems and other consequences of dementia.\u201d<\/p>\n<p>What do fans say?<\/p>\n<p>Robert Shaw, owner of Physical Structure, has taken Urolithin A for six months while managing common variable immunodeficiency. <\/p>\n<p>\u201cAt 59, I live with common variable immunodeficiency and receive monthly IVIG therapy,\u201d Shaw told The Post.<\/p>\n<p>\u201cTypically, by the third week after an infusion, I would feel fatigue and see elevated CRP levels. My goal in starting Urolithin A was to improve strength and help manage inflammation.\u201d <\/p>\n<p>The results surprised him. His bench press one-rep max increased from 200 to 245 pounds \u2014 \u201ca gain I didn\u2019t expect at this stage of life.\u201d<\/p>\n<p>Dr. Jenelle Kim, founder of JBK Wellness Labs, says Urolithin A supports mitophagy, the cellular process of clearing damaged mitochondria so healthier ones can thrive. Dr. Gabrielle Lyon<\/p>\n<p>\u201cJust as importantly, the fatigue I used to feel leading into my next IVIG treatment has eased significantly,\u201d he said.  \u201cWith no change in sleep schedule, I now feel more resilient and better recovered throughout the month.\u201d<\/p>\n<p>While Urolithin A \u201chasn\u2019t been a magic solution,\u201d Shaw said it has proven \u201ca valuable addition to my own performance and longevity strategy.\u201d<\/p>\n<p>With clients, he is careful not to prescribe supplements.<\/p>\n<p>\u201cWhat I do share are my personal experiences, including the benefits I\u2019ve seen with Urolithin A,\u201d he said. <\/p>\n<p>Studies show it can lead to \u201cimproved muscle strength, exercise performance and mito-health biomarkers.\u201d CandyRetriever  \u2013 stock.adobe.com<\/p>\n<p>\u201cAt the same time, I emphasize that real progress begins with lifestyle foundations: consistent sleep, proper hydration, daily sunlight, stress management and a protein-forward, nutrient-dense diet. Only after those are in place should supplements even enter the conversation.\u201d<\/p>\n<p>On Reddit, some people insist they\u2019ve noticed no real difference on the supplement, complaining about results that have amounted to \u201cnada, zilch, zero.\u201d<\/p>\n<p>But others rave about it. One wrote that they \u201cdefinitely hold more muscle mass when I\u2019m taking it,\u201d while another raved about feeling well rested even after very little sleep.<\/p>\n<p>The caveats<\/p>\n<p>\u201cThere is insufficient data at this point to recommend Urolithin A to pregnant or breastfeeding mothers and children under 18 years of age,\u201d Lyon said. <\/p>\n<p>Dr. Kavin Mistry notes Urolithin A improved biomarkers and endurance in trials but warns \u201cthis isn\u2019t a universal solution.\u201d Linkedin\/Dr. Kavin Mistry<\/p>\n<p>Still, she is emphatic: \u201cBased on the evidence, I take Urolithin A myself, I give it to those I love, and I recommend it for those interested in supporting healthy muscle function and cellular energy which I feel are essential to healthy longevity.\u201d <\/p>\n<p>Lyon made sure to note that she is a paid brand partner of Timeline, the Swiss-based global leader behind 10+ years of pioneering research on Urolithin A (Mitopure). <\/p>\n<p>For most people, it\u2019s considered safe at typical doses, although higher amounts may sometimes cause mild digestive upset like bloating or nausea. <\/p>\n<p>Even those who advocate for Urolithin A and who tout its benefits still insist on being cautious \u2014 emphasizing that Urolithin A is a tool, not the toolbox. <\/p>\n<p>Or, as Dr. Kavin Mistry, a board-certified neuroradiologist, academic and health educator based in Bethlehem, Penn., put it: \u201cI don\u2019t pitch it as a universal solution or as a replacement for exercise. If your pillars are shaky (sleep, training, protein, daylight, stress skills), UA is a nice amplifier, not the foundation. UA is a precision chisel, not the entire workshop.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"Urolithin A has been called the \u201cmitochondria makeover pill,\u201d a powerful fuel to trigger cellular regeneration that makes&hellip;\n","protected":false},"author":2,"featured_media":214133,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[61],"tags":[2594,97,1244,2749,269,673],"class_list":{"0":"post-214132","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-nutrition","8":"tag-aging","9":"tag-health","10":"tag-health-and-wellness-products","11":"tag-longevity","12":"tag-nutrition","13":"tag-wellness"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/214132","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/comments?post=214132"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/214132\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media\/214133"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media?parent=214132"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/categories?post=214132"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/tags?post=214132"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}