{"id":222454,"date":"2025-10-13T21:35:18","date_gmt":"2025-10-13T21:35:18","guid":{"rendered":"https:\/\/www.newsbeep.com\/us\/222454\/"},"modified":"2025-10-13T21:35:18","modified_gmt":"2025-10-13T21:35:18","slug":"college-football-betting-lines-ole-miss-georgia-tennessee-alabama-lead-top-25-matchups","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us\/222454\/","title":{"rendered":"College football betting lines: Ole Miss-Georgia, Tennessee-Alabama lead Top 25 matchups"},"content":{"rendered":"

Oct 13, 2025, 02:55 PM ET<\/p>\n

There are five ranked matchups in college football this weekend, the most in any week this season. Three of them are in the SEC — tying the conference record for the most in one week — with No. 10 LSU<\/a> taking on No. 17 Vanderbilt<\/a>, No. 5 Ole Miss<\/a> at No. 9 Georgia<\/a>, and No. 11 Tennessee<\/a> taking on No. 6 Alabama<\/a>, all on ABC.<\/p>\n

Editor’s Picks<\/a><\/a><\/p>\n

1 Related<\/p>\n

No. 20 USC<\/a> will face its longtime rival No. 13 Notre Dame<\/a>. The Big 12 will feature No. 23 Utah<\/a> taking on in-state rival No. 15 BYU<\/a>. Notre Dame and No. 23 Texas<\/a> are the only two-loss teams in the rankings.<\/p>\n

BYU is up to its highest ranking of the season, No. 12 Georgia Tech<\/a> (at Duke<\/a>) is up to its highest since 2014, No. 4 Texas A&M<\/a> (at Arkansas<\/a>) is up to its highest in 30 years, according to ESPN Research.<\/p>\n

Most notably, No. 3 Indiana<\/a> is up to its best ranking ever after beating Oregon<\/a> in Eugene. Oregon slips to No. 8 and will look to right the ship against Rutgers<\/a> on Saturday.<\/p>\n

See more: Power Rankings<\/a> | Betting Buzz<\/a><\/p>\n

All times Eastern. For latest lines, go to ESPN BET<\/a><\/p>\n

Louisville<\/a> at No. 2 Miami<\/a> -13.5
Friday, 7 p.m., ESPN<\/p>\n

Records: Louisville 4-1, 0-1 vs. AP Top 25 teams; Miami 5-0, 3-0 vs. AP Top 25 teams
Opening line: Miami -13.5, O\/U 54.5
Money line: Off
Over\/under: 53.5 (O EVEN, U -120)<\/p>\n

FPI projection:<\/a> Miami by 12.3 points with an 85% probability to win game outright<\/p>\n

No. 25 Nebraska<\/a> -6.5 at Minnesota<\/a>
Friday, 8 p.m., FOX<\/p>\n

Records: Nebraska 5-1, 0-1 vs. AP Top 25 teams; Minnesota 4-2, 0-1 vs. AP Top 25 teams
Opening line: Nebraska -5.5, O\/U 47.5
Money line: Off
Over\/under: 46.5 (O -110, U -110)<\/p>\n

FPI projection:<\/a> Nebraska by 7.2 points with a 75% probability to win game outright<\/p>\n

No. 10 LSU<\/a> at No. 17 Vanderbilt<\/a> -2.5
Saturday, noon, ABC<\/p>\n

Records: LSU 5-1, 1-1 vs. AP Top 25 teams; Vanderbilt 5-1, 1-1 vs. AP Top 25 teams
Opening line: Vanderbilt -2.5, O\/U 48.5
Money line: Off
Over\/under: 49.5 (O -105, U -115)<\/p>\n

FPI projection:<\/a> Vanderbilt by 2.8 points with a 61% probability to win game outright<\/p>\n

No. 12 Georgia Tech<\/a> at Duke<\/a> -2.5
Saturday, noon, ESPN<\/p>\n

Records: Georgia Tech 6-0, 1-0 vs. AP Top 25 teams; Duke 4-2, 0-1 vs. AP Top 25 teams
Opening line: Duke -2.5, O\/U 60.5
Money line: Off
Over\/under: 61.5 (O -105, U -115)<\/p>\n

FPI projection:<\/a> Duke by 3 points with a 62% probability to win game outright<\/p>\n

No. 14 Oklahoma<\/a> -4.5 at South Carolina<\/a>
Saturday, 12:45 p.m., SEC Network<\/p>\n

Records: Oklahoma 5-1, 2-0 vs. AP Top 25 teams; South Carolina 3-3, 0-2 vs. AP Top 25 teams
Opening line: Oklahoma -4.5, O\/U 42.5
Money line: Off
Over\/under: 43.5 (O -105, U -115)<\/p>\n

FPI projection:<\/a> Oklahoma by 1.2 points with a 55% probability to win game outright<\/p>\n

No. 1 Ohio State<\/a> -27.5 at Wisconsin<\/a>
Saturday, 3:30 p.m., CBS<\/p>\n

Records: Ohio State 6-0, 2-0 vs. AP Top 25 teams; Wisconsin 2-4, 0-2 vs. AP Top 25 teams
Opening line: Ohio State -26.5, O\/U 41.5
Money line: Off
Over\/under: 41.5 (O -115, U -105)<\/p>\n

FPI projection:<\/a> Ohio State by 23.3 points with a 95% probability to win game outright<\/p>\n

Michigan State<\/a> at No. 3 Indiana<\/a> -26.5
Saturday, 3:30 p.m., Peacock<\/p>\n

Records: Michigan State 3-3, 0-1 vs. AP Top 25 teams; Indiana 6-0, 2-0 vs. AP Top 25 teams
Opening line: Indiana -26.5, O\/U 54.5
Money line: Off
Over\/under: 53.5 (O -105, U -115)<\/p>\n

FPI projection:<\/a> Indiana by 26.8 points with a 96% probability to win game outright<\/p>\n

No. 4 Texas A&M<\/a> -7.5 at Arkansas<\/a>
Saturday, 3:30 p.m., ESPN<\/p>\n

Records: Texas A&M 6-0, 1-0 vs. AP Top 25 teams; Arkansas 2-4, 0-3 vs. AP Top 25 teams
Opening line: Texas A&M -7.5, O\/U 62.5
Money line: Off
Over\/under: 62.5 (O -110, U -110)<\/p>\n

FPI projection:<\/a> Texas A&M by 5.3 points with a 70% probability to win game outright<\/p>\n

No. 5 Ole Miss<\/a> at No. 9 Georgia<\/a> -7.5
Saturday, 3:30 p.m., ABC<\/p>\n

Records: Ole Miss 6-0, 1-0 vs. AP Top 25 teams; Georgia 5-1, 1-1 vs. AP Top 25 teams
Opening line: Georgia -6.5, O\/U 54.5
Money line: Off
Over\/under: 55.5 (O -105, U -115)<\/p>\n

FPI projection:<\/a> Georgia by 5.2 points with a 70% probability to win game outright<\/p>\n

No. 7 Texas Tech<\/a> -10.5 at Arizona State<\/a>
Saturday, 4 p.m., FOX<\/p>\n

Records: Texas Tech 6-0, 1-0 vs. AP Top 25 teams; Arizona State 4-2, 1-0 vs. AP Top 25 teams
Opening line: Texas Tech -10.5, O\/U 49.5
Money line: Off
Over\/under: 48.5 (O -110, U -110)<\/p>\n

FPI projection:<\/a> Texas Tech by 7.3 points with a 76% probability to win game outright<\/p>\n

No. 22 Memphis<\/a> -21.5 at UAB<\/a>
Saturday, 4 p.m., ESPN2<\/p>\n

Records: Memphis 6-0, 0-0 vs. AP Top 25 teams; UAB 2-4, 0-1 vs. AP Top 25 teams
Opening line: Memphis -21.5, O\/U 64.5
Money line: Off
Over\/under: 64.5 (O -105, U -115)<\/p>\n

FPI projection:<\/a> Memphis by 25.6 points with a 96% probability to win game outright<\/p>\n

No. 8 Oregon<\/a> -16.5 at Rutgers<\/a>
Saturday, 6:30 p.m., BTN<\/p>\n

Records: Oregon 5-1, 1-1 vs. AP Top 25 teams; Rutgers 3-3, 0-0 vs. AP Top 25 teams
Opening line: Oregon -15.5, O\/U 59.5
Money line: Off
Over\/under: 60.5 (O -110, U -110)<\/p>\n

FPI projection:<\/a> Oregon by 11.5 points with an 84% probability to win game outright<\/p>\n

Washington State<\/a> at No. 18 Virginia<\/a> -17.5
Saturday, 6:30 p.m., The CW Network<\/p>\n

Records: Washington State 3-3, 0-1 vs. AP Top 25 teams; Virginia 5-1, 1-0 vs. AP Top 25 teams
Opening line: Virginia -16.5, O\/U 57.5
Money line: Off
Over\/under: 56.5 (O -115, U -105)<\/p>\n

FPI projection:<\/a> Virginia by 18.7 points with a 92% probability to win game outright<\/p>\n

No. 21 Texas<\/a> -10.5 at Kentucky<\/a>
Saturday, 7 p.m., ESPN<\/p>\n

Records: Texas 4-2, 1-1 vs. AP Top 25 teams; Kentucky 2-3, 0-2 vs. AP Top 25 teams
Opening line: Texas -12.5, O\/U 43.5
Money line: Off
Over\/under: 43.5 (O EVEN, U -120)<\/p>\n

FPI projection:<\/a> Texas by 10.6 points with an 82% probability to win game outright<\/p>\n

No. 11 Tennessee<\/a> at No. 6 Alabama<\/a> -9.5
Saturday, 7:30 p.m., ABC<\/p>\n

Records: Tennessee 5-1, 0-1 vs. AP Top 25 teams; Alabama 5-1, 3-0 vs. AP Top 25 teams
Opening line: Alabama -7.5, O\/U 60.5
Money line: Off
Over\/under: 59.5 (O -105, U -115)<\/p>\n

FPI projection:<\/a> Alabama by 6.1 points with a 72% probability to win game outright<\/p>\n

No. 20 USC<\/a> at No. 13 Notre Dame<\/a> -8.5
Saturday, 7:30 p.m., NBC, Peacock<\/p>\n

Records: USC 5-1, 1-1 vs. AP Top 25 teams; Notre Dame 4-2, 0-2 vs. AP Top 25 teams
Opening line: Notre Dame -7.5, O\/U 61.5
Money line: Off
Over\/under: 61.5 (O -105, U -115)<\/p>\n

FPI projection:<\/a> Notre Dame by 5.1 points with a 69% probability to win game outright<\/p>\n

Florida Atlantic<\/a> at No. 19 South Florida<\/a> -21.5
Saturday, 7:30 p.m., ESPNU<\/p>\n

Records: Florida Atlantic 3-3, 0-0 vs. AP Top 25 teams; South Florida 5-1, 2-1 vs. AP Top 25 teams
Opening line: South Florida -22.5, O\/U 74.5
Money line: Off
Over\/under: 73.5 (O -115, U -105)<\/p>\n

FPI projection:<\/a> South Florida by 19.8 points with a 93% probability to win game outright<\/p>\n

No. 16 Missouri<\/a> at Auburn<\/a> -1.5
Saturday, 7:45 p.m., SEC Network<\/p>\n

Records: Missouri 5-1, 0-1 vs. AP Top 25 teams; Auburn 3-3, 0-3 vs. AP Top 25 teams
Opening line: Auburn -2.5, O\/U 44.5
Money line: Off
Over\/under: 44.5 (O EVEN, U -120)<\/p>\n

FPI projection:<\/a> Missouri by 0.9 points with a 54% probability to win game outright<\/p>\n

No. 23 Utah<\/a> -3.5 at No. 15 BYU<\/a>
Saturday, 8 p.m., FOX<\/p>\n

Records: Utah 5-1, 1-1 vs. AP Top 25 teams; BYU 6-0, 0-0 vs. AP Top 25 teams
Opening line: Utah -3.5, O\/U 47.5
Money line: Off
Over\/under: 48.5 (O -115, U -105)<\/p>\n

FPI projection:<\/a> BYU by 0.2 points with a 51% probability to win game outright<\/p>\n

No. 24 Cincinnati<\/a> -21.5 at Oklahoma State<\/a>
Saturday, 8 p.m., ESPN2<\/p>\n

Records: Cincinnati 5-1, 1-0 vs. AP Top 25 teams; Oklahoma State 1-5, 0-1 vs. AP Top 25 teams
Opening line: Cincinnati -20.5, O\/U 57.5
Money line: Off
Over\/under: 58.5 (O -105, U -115)<\/p>\n

FPI projection:<\/a> Cincinnati by 18.2 points with a 91% probability to win game outright<\/p>\n","protected":false},"excerpt":{"rendered":"Oct 13, 2025, 02:55 PM ET There are five ranked matchups in college football this weekend, the most…\n","protected":false},"author":2,"featured_media":222455,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[67],"tags":[399,398,396,397,99],"class_list":{"0":"post-222454","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-ncaa-football","8":"tag-football","9":"tag-ncaa","10":"tag-ncaa-football","11":"tag-ncaafootball","12":"tag-sports"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/222454","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/comments?post=222454"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/222454\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media\/222455"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media?parent=222454"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/categories?post=222454"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/tags?post=222454"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}