{"id":284849,"date":"2025-11-11T07:24:20","date_gmt":"2025-11-11T07:24:20","guid":{"rendered":"https:\/\/www.newsbeep.com\/us\/284849\/"},"modified":"2025-11-11T07:24:20","modified_gmt":"2025-11-11T07:24:20","slug":"at-aasld-optimism-about-ai-hep-delta-and-madrigals-mash-drug","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us\/284849\/","title":{"rendered":"At AASLD, optimism about AI, Hep delta and Madrigal\u2019s MASH drug"},"content":{"rendered":"<p class=\"author-bio\">Isabella Cueto covers the leading causes of death and disability: chronic diseases. Her focus includes autoimmune conditions and diseases of the lungs, kidneys, liver (and more). She writes about intriguing research, the promises and pitfalls of treatment, and what can be done about the burden of disease. You can reach Isabella on Signal at isabellacueto.03.<\/p>\n<p>This is the online version of AASLD in 30 Seconds, the latest from the American Association for the Study of Liver Diseases\u2019s Liver Meeting. Sign up\u00a0<a href=\"https:\/\/www.statnews.com\/signup\/aasld-in-30-seconds\/\" rel=\"nofollow noopener\" target=\"_blank\">here<\/a>\u00a0to get it in your inbox.<\/p>\n<p>Good morning. D.C.\u2019s first big cold snap rolled in overnight! RIP to the backyard gardens. Grab a hot bev, and let\u2019s get into the latest liver news.<\/p>\n<p>Rezdiffra updates to tide us over until 2027<\/p>\n<p>Sunday brought new data from key event sponsor Madrigal about its MASH drug resmetirom, the daily pill sold under the brand name Rezdiffra, which was granted <a href=\"https:\/\/www.statnews.com\/2024\/03\/14\/madrigal-mash-drug-approval\/\" rel=\"nofollow noopener\" target=\"_blank\">accelerated FDA approval<\/a> last year. Crucial information about the drug\u2019s effects on outcomes like MELD score and liver-related mortality are still to come \u2014 topline results from <a href=\"https:\/\/clinicaltrials.gov\/study\/NCT05500222\" target=\"_blank\" rel=\"noopener nofollow\">MAESTRO-NASH OUTCOMES<\/a> are due in 2027. In the meantime, Sunday\u2019s oral presentation highlighted the need for MASH patients to get consistent treatment in order to hold onto benefits.<\/p>\n<p class=\"restricted-text\">STAT+ Exclusive Story<\/p>\n<p class=\"restricted-login\">Already have an account? <a href=\"https:\/\/www.statnews.com\/login\/\" data-stat-login=\"\" data-stat-paywall-cta=\"breaker login cta\" rel=\"nofollow noopener\" target=\"_blank\">Log in<\/a><\/p>\n<p>\t\t\t<img decoding=\"async\" class=\"restricted-content-breaker-bg\" src=\"https:\/\/www.newsbeep.com\/us\/wp-content\/uploads\/2025\/07\/stat-plus-breaker-bg.png\" alt=\"STAT+\"\/><\/p>\n<p>\t\t\t\t\t<a href=\"https:\/\/www.statnews.com\/stat-plus\/\" rel=\"nofollow noopener\" target=\"_blank\"><br \/>\n\t\t\t\t\t\t<img decoding=\"async\" class=\"stat-plus-logo\" src=\"https:\/\/www.statnews.com\/wp-content\/themes\/stat\/images\/stat-plus-logo-white.svg\" alt=\"STAT+\"\/><br \/>\n\t\t\t\t\t<\/a><\/p>\n<p>\t\t\t\tThis article is exclusive to STAT+ subscribers<br \/>\n\t\t\t\tUnlock this article \u2014 plus in-depth analysis, newsletters, premium events, and news alerts.<\/p>\n<p class=\"restricted-content-breaker-wrapper-cta mobile\">Already have an account? <a href=\"https:\/\/www.statnews.com\/login\/\" data-stat-login=\"\" data-stat-paywall-cta=\"breaker login cta mobile\" rel=\"nofollow noopener\" target=\"_blank\">Log in<\/a><\/p>\n<p>\t\t\t\t\t\tIndividual plans<\/p>\n<p>\t\t\t\t\t\tGroup plans<\/p>\n<p>\t\t\t\t<a href=\"https:\/\/www.statnews.com\/stat-plus\/\" class=\"stat-button view-all\" data-stat-paywall-cta=\"breaker view all plans\" aria-label=\"View All Plans\" rel=\"nofollow noopener\" target=\"_blank\">View All Plans<\/a><\/p>\n<p class=\"restricted-content-text\">\n\t\t\t\t\t\tTo read the rest of this story subscribe to STAT+.\t\t\t\t\t<\/p>\n<p>\t\t\t\t\t<a href=\"https:\/\/www.statnews.com\/stat-plus\/\" class=\"stat-button restricted-button\" data-stat-paywall-cta=\"breaker subscribe cta 1\" rel=\"nofollow noopener\" target=\"_blank\">Subscribe<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"Isabella Cueto covers the leading causes of death and disability: chronic diseases. Her focus includes autoimmune conditions and&hellip;\n","protected":false},"author":2,"featured_media":284850,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[59],"tags":[9038,182,10743,16347,97,252,37583,253,248],"class_list":{"0":"post-284849","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-health-care","8":"tag-addiction","9":"tag-ai","10":"tag-biotech","11":"tag-chronic-disease","12":"tag-health","13":"tag-health-care","14":"tag-health-tech","15":"tag-healthcare","16":"tag-stat"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/284849","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/comments?post=284849"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/284849\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media\/284850"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media?parent=284849"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/categories?post=284849"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/tags?post=284849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}