{"id":299461,"date":"2025-11-18T16:56:11","date_gmt":"2025-11-18T16:56:11","guid":{"rendered":"https:\/\/www.newsbeep.com\/us\/299461\/"},"modified":"2025-11-18T16:56:11","modified_gmt":"2025-11-18T16:56:11","slug":"pbm-revolution-cubans-stelara-challenge-express-scripts-price-games-u-s-drug-spending-reality-and-the-afp-reckoning","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us\/299461\/","title":{"rendered":"PBM Revolution, Cuban\u2019s Stelara Challenge, Express Scripts\u2019 Price Games, U.S. Drug Spending Reality, and the AFP Reckoning"},"content":{"rendered":"<p><a href=\"https:\/\/www.drugchannels.net\/2025\/11\/drug-channels-news-roundup-november.html\" style=\"clear: right; display: block; float: right; padding-left: 8px; text-align: center;\" rel=\"nofollow noopener\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" alt=\"\" border=\"0\" data-original-height=\"768\" data-original-width=\"512\" height=\"251\" src=\"https:\/\/www.newsbeep.com\/us\/wp-content\/uploads\/2025\/11\/Bearista-resize.png\" width=\"167\"\/><\/a>Happy Thanksgiving, everyone! Before you stretch your stomach, stretch your mind with some fresh food for thought from across the drug channel. In this issue:<\/p>\n<p>Plus: <a href=\"https:\/\/www.drugchannels.net\/2025\/11\/drug-channels-news-roundup-november.html#story5\" rel=\"nofollow noopener\" target=\"_blank\">Has the day of reckoning arrived for shady alternative funding vendors?<\/a><\/p>\n<p>P.S. <a href=\"https:\/\/drugch.nl\/AJF-LinkedIn\" target=\"_blank\" rel=\"nofollow noopener\">Join my more than 66,000 LinkedIn followers<\/a> for daily links to neat stuff, along with sharp and thoughtful commentary from the DCI community.<\/p>\n<p style=\"border-color: #FF0000; border-style: solid; border: 3px solid rgb(255, 0, 0); padding: 1em;\">What else should you expect for 2026? Find out during my upcoming live video webinar, <a href=\"https:\/\/drugch.nl\/outlook2026\" target=\"_blank\" rel=\"nofollow noopener\">Drug Channels Outlook 2026<\/a>, on December 12, 2025, from 12:00 p.m. to 1:30 p.m. ET. <a href=\"https:\/\/drugch.nl\/outlook2026\" target=\"_blank\" rel=\"nofollow noopener\">Click here to learn more and sign up.<\/a> As always, we are offering special discounts if you want to bring your whole team. <\/p>\n<p><a name=\"more\"\/><br \/>\n<br \/><a href=\"https:\/\/drugch.nl\/4opqFou\" target=\"_blank\" rel=\"nofollow noopener\">Best Practices in Healthcare Survey Webinar<\/a>, WTW<br \/>\n<br \/><a href=\"https:\/\/drugch.nl\/47Zy6xc\" target=\"_blank\" rel=\"nofollow noopener\">Mark Cuban Cost Plus Drug Company Expands Access with Addition of Starjemza\u00ae (ustekinumab-hmny) to Give Patients More Power Over Prescription Costs<\/a>, PR Newswire<br \/>\n<br \/>Cuban\u2019s Cost Plus Drug Company has launched Starjemza\u2014a biosimilar of Stelara\u2014with a cash price that\u2019s a whopping 99% below the reference product.<\/p>\n<p>Cuban once again exposes the economic contradictions of the drug channel. PBM-affiliated private-label biosimilars have strong formulary positions, despite having much higher list prices than competing biosimilars. See <a href=\"https:\/\/www.drugchannels.net\/2025\/07\/the-stelara-biosimilar-price-war-how.html\" target=\"_blank\" rel=\"nofollow noopener\">The Stelara Biosimilar Price War: How PBM-Affiliated Private Labels Are Reshaping the Market<\/a>.\n<\/p>\n<p>Of course, PBMs can lower list prices of their affiliate\u2019s private label drugs at any time, but \u00af\\_(\u30c4)_\/\u00af.\n<\/p>\n<p>This approach also establishes a powerful cash-pay benchmark that could disrupt many benefit designs\u2014if plan sponsors can break their addiction to rebates and fully embrace truly low-cost products. (<a href=\"https:\/\/www.linkedin.com\/feed\/update\/urn:li:activity:7394860366784245762\/\" target=\"_blank\" rel=\"nofollow noopener\">It also led to this first rate meme.<\/a>) We&#8217;ll see if the WTW survey results above are real. <\/p>\n<p><a href=\"https:\/\/drugch.nl\/47KodSP\" target=\"_blank\" rel=\"nofollow noopener\"> This drug pricing distortion was supposed to go extinct. It\u2019s never been more alive.<\/a>, 46brooklyn Research<br \/>\n<br \/>Kudos to Antonio Ciaccia and the 46brooklyn Research team for another stellar piece of drug channel sleuthing.<\/p>\n<p>Their latest report exposes questionable generic drug pricing practices within Cigna\/Evernorth\u2019s Quallent Pharmaceuticals business.\n<\/p>\n<p>As their analysis shows, the Quallent\u2019s average AWP-to-WAC ratio was 1.38x\u2014well above the industry standard of 1.20x. At least one product had a ratio of 2.00x. Plan sponsors using AWP-based reimbursement could be overpaying substantially.\n<\/p>\n<p>[Click to Enlarge]<\/p>\n<p><a href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEiIUUc6MWXM25RzIYCtsncvUbAMyG1rSGHoJBACryHkBqPM0NO6PnePjbrum7MyH0eDslLf1gvnW-ihUPm42iINO7Ki3OVX-jD5IADCCDgI8NDjTuBtefrxVue8gu2gfl2-qRJ7cTHIj6aoNd5o2imaIzUq-9UYrK8fMKTqNHsgSxSXgGqLXH4qDw\/s1600\/AWP-to-WAC.png\" style=\"display: block; padding: 0em 0px; text-align: center;\" rel=\"nofollow noopener\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" alt=\"\" border=\"0\" data-original-height=\"772\" data-original-width=\"1208\" height=\"327\" src=\"https:\/\/www.newsbeep.com\/us\/wp-content\/uploads\/2025\/11\/AWP-to-WAC.png\" width=\"512\"\/><\/a><br \/>\n<br \/>If these figures are accurate, it\u2019s yet another reminder: Always check your contract&#8217;s math.<\/p>\n<p>So far, Cigna has offered no rebuttal or explanation, but I\u2019ll share one if it arrives.<\/p>\n<p><a href=\"https:\/\/drugch.nl\/4qoWlfE\" target=\"_blank\" rel=\"nofollow noopener\">Drug Expenditure Dynamics 2000\u20132022<\/a>, IQVIA<br \/>\n<br \/>IQVIA again uses data to provide a counterintuitive reality check on the political rhetoric.<\/p>\n<p>Across 12 major countries, net drug spending accounts for only 9% to 21% of total healthcare costs.\n<\/p>\n<p>Despite the political noise, U.S. drug spending is\u2014and has been\u2014squarely in the middle of the global pack. Note that these figures include spending on both retail and non-retail drugs, net of rebates and discounts.\n<\/p>\n<p>[Click to Enlarge]<\/p>\n<p><a href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEjD7s3P5zhluxJ9zmLLKnDG-yW5BB-wl29jJ2cVikJc0B3ItX7Z447At4lHqjSsU_bW6iDYEjN9u_YWTA-AV2eTNcvqTdjzkRdfmwX4I3D4Z7KnhbX0XofgGVk08Lc0pBmvcTMTjj2ALKtaf0MEepndv2cFullGBY7qp2Lx-eCFghqm6eGa-O6iEA\/s1600\/IQVIA-global-2022.png\" style=\"display: block; padding: 0em 0px; text-align: center;\" rel=\"nofollow noopener\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" alt=\"\" border=\"0\" data-original-height=\"378\" data-original-width=\"942\" height=\"206\" src=\"https:\/\/www.newsbeep.com\/us\/wp-content\/uploads\/2025\/11\/IQVIA-global-2022.png\" width=\"512\"\/><\/a><br \/>\n<br \/>Everything in the U.S. healthcare system is more expensive. That&#8217;s one of the reasons that benchmarking one small part of the system\u2014the brand-name drug share of the figures above\u2014makes little sense. <a href=\" https:\/\/www.drugchannels.net\/2025\/05\/drug-channels-news-roundup-may-2025-mfn.html#story1\" target=\"_blank\">See my comments from last May.<\/a><\/p>\n<p>As usual, <a href=\"https:\/\/www.linkedin.com\/posts\/adamjfein_healthcare-drug-healthcare-activity-7390919450239328256-pLuk \" target=\"_blank\" rel=\"nofollow noopener\">this report sparked a spirited online debate<\/a>\u2014although some commenters seemed not to have read past the headline and opened the actual report. \ud83d\ude11<\/p>\n<p><a href=\"https:\/\/drugch.nl\/49SlcCD\" target=\"_blank\" rel=\"nofollow noopener\">Cheaper medicines, free beach trips: U.S. health plans tap prescriptions that feds say are illegal<\/a>, CNBC<br \/>\n<br \/>Has the day of reckoning arrived for such shady alternative funding programs (AFPs) like PriceMD, Rx Valet, SHARx, and others?<\/p>\n<p>This powerful CNBC expos\u00e9 reveals how shady AFPs skirt FDA regulations and guidance by sourcing specialty drugs from &#8220;unverified suppliers&#8221; and &#8220;potentially illicit&#8221; online pharmacies.\n<\/p>\n<p>Employers keep chasing these schemes, creating delays, denials, confusion, and real risks for their beneficiaries. One quibble: The article omits the plans\u2019 decision to exclude specialty drugs from the formulary, so that a patient technically has &#8220;no coverage&#8221; (wink, wink) for the drug.\n<\/p>\n<p><a href=\"https:\/\/www.drugchannels.net\/2023\/05\/employers-expand-use-of-alternative.html\" target=\"_blank\" rel=\"nofollow noopener\">As I have long argued<\/a>, it\u2019s long past time to hold AFPs accountable and stop these dangerous workarounds.\n<\/p>\n<p>If you have 30 minutes, I highly encourage you to watch the entire video.\n<\/p>\n<\/p>\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"Happy Thanksgiving, everyone! Before you stretch your stomach, stretch your mind with some fresh food for thought from&hellip;\n","protected":false},"author":2,"featured_media":299462,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[58],"tags":[97,243],"class_list":{"0":"post-299461","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-medication","8":"tag-health","9":"tag-medication"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/299461","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/comments?post=299461"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/299461\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media\/299462"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media?parent=299461"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/categories?post=299461"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/tags?post=299461"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}