The Novo Nordisk A\/S headquarters in Bagsvaerd, Denmark, on Wednesday, Nov. 5, 2025. <\/p>\n
Nichlas Pollier | Bloomberg | Getty Images<\/p>\n
Shares of Novo Nordisk on Monday fell as much 11% after the Danish drug pharmaceutical company said a highly-anticipated trial for Alzheimer’s disease failed to meet its main goal.<\/p>\n
The trial tested whether semaglutide\u00a0\u2014 the active ingredient in Novo’s blockbuster diabetes and weight loss drugs Ozempic and Wegovy \u2014 helped slow progression for Alzheimer’s disease. <\/p>\n
While treatment with semaglutide resulted in improvement of Alzheimer’s disease-related biomarkers in two separate trials, this did not translate into a delay of disease progression, Novo said in a statement Monday. The goal had been to slow patient’s cognitive decline by at least 20%.<\/p>\n
Analysts had prior to the results called the trials a long shot, whereas Novo itself had referred it as a “lottery ticket.”<\/p>\n
Novo stock was down 8.3% to 279 Danish kroner as of 11:50 a.m. GMT (6:50 a.m. ET). <\/p>\n
This is breaking news. Please refresh for updates.<\/p>\n","protected":false},"excerpt":{"rendered":"The Novo Nordisk A\/S headquarters in Bagsvaerd, Denmark, on Wednesday, Nov. 5, 2025. Nichlas Pollier | Bloomberg |…\n","protected":false},"author":2,"featured_media":310753,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[59],"tags":[1050,28,122,97,252,2601,253,247],"class_list":["post-310752","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health-care","tag-breaking-news-europe","tag-business","tag-business-news","tag-health","tag-health-care","tag-health-care-industry","tag-healthcare","tag-pharmaceuticals"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/310752","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/comments?post=310752"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/310752\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media\/310753"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media?parent=310752"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/categories?post=310752"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/tags?post=310752"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}