{"id":333570,"date":"2025-12-06T12:29:30","date_gmt":"2025-12-06T12:29:30","guid":{"rendered":"https:\/\/www.newsbeep.com\/us\/333570\/"},"modified":"2025-12-06T12:29:30","modified_gmt":"2025-12-06T12:29:30","slug":"supercomputer-creates-one-of-the-most-realistic-virtual-brains-ever-seen-sciencealert","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us\/333570\/","title":{"rendered":"Supercomputer Creates One of The Most Realistic Virtual Brains Ever Seen : ScienceAlert"},"content":{"rendered":"<p>Getting a better understanding of <a href=\"https:\/\/www.sciencealert.com\/your-brain-goes-through-5-distinct-epochs-massive-study-finds\" rel=\"nofollow noopener\" target=\"_blank\">how the brain works<\/a> is tricky, as living brains aren&#8217;t easily prodded and analyzed. Scientists now have a new simulation of a mouse&#8217;s brain to refer to \u2013 one of the most comprehensive that&#8217;s ever been put together.<\/p>\n<p>The creation was led by a team from the Allen Institute in the US and the University of Electro-Communications in Japan, and it may allow diseases <a href=\"https:\/\/www.sciencealert.com\/alzheimer-s-disease\" rel=\"nofollow noopener\" target=\"_blank\">such as Alzheimer&#8217;s<\/a> to be modeled and studied in greater detail.<\/p>\n<p>The simulation models an <a href=\"https:\/\/en.wikipedia.org\/wiki\/Cerebral_cortex\" rel=\"nofollow noopener\" target=\"_blank\">entire mouse cortex<\/a>. While this isn&#8217;t nearly as large or as intricate as a human brain, which contains <a href=\"https:\/\/doi.org\/10.1093\/brain\/awae390\" rel=\"nofollow noopener\" target=\"_blank\">billions of neurons<\/a>, there are <a href=\"https:\/\/news.harvard.edu\/gazette\/story\/2023\/09\/human-brain-too-big-to-map-so-theyre-starting-with-mice\/\" rel=\"nofollow noopener\" target=\"_blank\">similarities<\/a> between human and rodent brains \u2013 so this could be a useful study tool.<\/p>\n<p>Related: <a href=\"https:\/\/www.sciencealert.com\/boosting-one-protein-reawakens-aging-brain-cells-in-mice-study-shows\" rel=\"nofollow noopener\" target=\"_blank\">Boosting One Protein Reawakens Aging Brain Cells in Mice, Study Shows<\/a><\/p>\n<p>The numbers are impressive: the virtual brain contains 9 million neurons, as well as 26 billion synapses (<a href=\"https:\/\/www.sciencealert.com\/millions-of-silent-synapses-could-be-the-key-to-lifelong-learning\" rel=\"nofollow noopener\" target=\"_blank\">neuron connectors<\/a>). There are 86 interconnected regions in the brain simulation, and it can process quadrillions of calculations every second.<\/p>\n<p>To put that in perspective, the real and full mouse brain <a href=\"https:\/\/www.hhmi.org\/news\/mouselight-project-maps-1000-neurons-and-counting-mouse-brain\" rel=\"nofollow noopener\" target=\"_blank\">contains<\/a> roughly 70 million neurons in a space about the size of an almond.<\/p>\n<\/p>\n<p>&#8220;This shows the door is open,&#8221; <a href=\"https:\/\/alleninstitute.org\/news\/one-of-worlds-most-detailed-virtual-brain-simulations-is-changing-how-we-study-the-brain\/\" rel=\"nofollow noopener\" target=\"_blank\">says<\/a> computational neuroscientist Anton Arkhipov, from the Allen Institute. &#8220;We can run these kinds of brain simulations effectively with enough computing power.&#8221;<\/p>\n<p>&#8220;It&#8217;s a technical milestone giving us confidence that much larger models are not only possible, but achievable with precision and scale.&#8221;<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/www.newsbeep.com\/us\/wp-content\/uploads\/2025\/12\/BrainModel.jpg\" alt=\"Brain model detail\" width=\"642\" height=\"159\" class=\"wp-image-183655 size-full\"   loading=\"lazy\"\/>The simulation enables researchers to track the activity of individual neurons. (Kuriyama et al., 2025).<\/p>\n<p>The complexity of the simulation means that researchers can watch as models of cognition,  <a href=\"https:\/\/www.sciencealert.com\/consciousness\" class=\"lar_link lar_link_outgoing\" data-linkid=\"73104\" data-postid=\"183652\" rel=\"nofollow noopener\" target=\"_self\">consciousness<\/a>, and disease <a href=\"https:\/\/www.sciencealert.com\/this-severe-brain-disorder-is-common-but-often-goes-undiagnosed\" rel=\"nofollow noopener\" target=\"_blank\">spread through the brain<\/a>. It&#8217;s a three-dimensional, moving map that shows individual neurons firing and connecting.<\/p>\n<p>Some of the ways this could be used, according to the researchers, are to test hypotheses on how seizures spread in the brain, or how brain waves <a href=\"https:\/\/www.sciencealert.com\/your-brain-has-a-hidden-rhythm-and-it-may-reveal-how-smart-you-are\" rel=\"nofollow noopener\" target=\"_blank\">contribute to focus<\/a> \u2013 without any need for repeated, invasive, physical brain scans.<\/p>\n<p>The necessary computing power was provided by <a href=\"https:\/\/www.sciencealert.com\/breakthrough-simulation-maps-every-star-in-the-milky-way-in-scientific-first\" rel=\"nofollow noopener\" target=\"_blank\">the Fugaku supercomputer<\/a> in Japan, which built upon existing cell databases and charts to form the model. The team also developed new software to more efficiently process brain activity and keep unnecessary calculations down to a minimum.<\/p>\n<p><a href=\"https:\/\/www.sciencealert.com\/newsletter?utm_source=promo_generic_health\" rel=\"nofollow noopener\" target=\"_blank\"><img decoding=\"async\" src=\"https:\/\/www.newsbeep.com\/us\/wp-content\/uploads\/2025\/12\/Generic-Health-Promo-Final-642x273.jpg\" alt=\"Subscribe to ScienceAlert's free fact-checked newsletter\" width=\"642\" height=\"273\" class=\"alignnone wp-image-182810 size-medium\"   loading=\"lazy\"\/><\/a><\/p>\n<p>&#8220;Fugaku is used for research in a wide range of computational science fields, such as astronomy, meteorology, and drug discovery, contributing to the resolution of many societal problems,&#8221; <a href=\"https:\/\/alleninstitute.org\/news\/one-of-worlds-most-detailed-virtual-brain-simulations-is-changing-how-we-study-the-brain\/\" rel=\"nofollow noopener\" target=\"_blank\">says<\/a> computer scientist Tadashi Yamazaki, from the University of Electro-Communications.<\/p>\n<p>&#8220;On this occasion, we utilized Fugaku for a neural circuit simulation.&#8221;<\/p>\n<p>Our brains are, of course, essential to good physical and mental health, and healthy old age \u2013 and studies of virtual <a href=\"https:\/\/www.sciencealert.com\/a-tiny-piece-of-mouse-brain-has-finally-been-mapped-in-mindblowing-detail\" rel=\"nofollow noopener\" target=\"_blank\">brain maps<\/a> and <a href=\"https:\/\/www.sciencealert.com\/breakthrough-helps-scientists-grow-more-realistic-human-brain-models\" rel=\"nofollow noopener\" target=\"_blank\">mini-brain structures<\/a> are going to be crucial in learning more about how this organ works, and how it can break down.<\/p>\n<p>The team has already been busy putting their new model to use, making discoveries about <a href=\"https:\/\/www.sciencealert.com\/brain-waves-move-in-opposite-directions-for-memorizing-and-recalling\" rel=\"nofollow noopener\" target=\"_blank\">brain wave synchronization<\/a> and the way the two hemispheres of the mouse brain interact with each other.<\/p>\n<p>It&#8217;s a massively impressive feat of computing and biological modeling, but the researchers have even grander plans, and one day want to build a full-sized model of a human brain inside a virtual computing space.<\/p>\n<p>&#8220;Our long-term goal is to build whole-brain models, eventually even human models, using all the biological details our Institute is uncovering,&#8221; <a href=\"https:\/\/alleninstitute.org\/news\/one-of-worlds-most-detailed-virtual-brain-simulations-is-changing-how-we-study-the-brain\/\" rel=\"nofollow noopener\" target=\"_blank\">says<\/a> Arkhipov. &#8220;We&#8217;re now moving from modeling single brain areas to simulating the entire brain of the mouse.&#8221;<\/p>\n<p>The research has been presented at the <a href=\"https:\/\/sc25.supercomputing.org\/\" rel=\"nofollow noopener\" target=\"_blank\">SC25 supercomputing conference<\/a>, and is <a href=\"https:\/\/doi.org\/10.1145\/3712285.3759819\" rel=\"nofollow noopener\" target=\"_blank\">available online<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"Getting a better understanding of how the brain works is tricky, as living brains aren&#8217;t easily prodded and&hellip;\n","protected":false},"author":2,"featured_media":333571,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[34],"tags":[97,1352],"class_list":["post-333570","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-health","tag-msft-content"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/333570","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/comments?post=333570"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/333570\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media\/333571"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media?parent=333570"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/categories?post=333570"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/tags?post=333570"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}