{"id":514908,"date":"2026-03-10T11:31:21","date_gmt":"2026-03-10T11:31:21","guid":{"rendered":"https:\/\/www.newsbeep.com\/us\/514908\/"},"modified":"2026-03-10T11:31:21","modified_gmt":"2026-03-10T11:31:21","slug":"vertex-says-drug-reduced-marker-of-kidney-disease-in-late-stage-trial","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us\/514908\/","title":{"rendered":"Vertex says drug reduced marker of kidney disease in late-stage trial"},"content":{"rendered":"<p>Vertex said Monday that a drug it secured as part of a <a href=\"https:\/\/www.statnews.com\/2024\/04\/10\/vertex-to-buy-alpine-immune-sciences\/\" rel=\"nofollow noopener\" target=\"_blank\">$4.9 billion acquisition<\/a> successfully reduced by half a key marker of a kidney disease known as IgA nephropathy.<\/p>\n<p>The results, from a Phase 3 trial, match data from a study of Otsuka\u2019s <a href=\"https:\/\/www.statnews.com\/2025\/11\/25\/fda-approves-otsuka-kidney-disease-therapy\/\" rel=\"nofollow noopener\" target=\"_blank\">recently approved Voyxact<\/a> and are numerically superior to data released last year by <a href=\"https:\/\/www.statnews.com\/2025\/06\/02\/vera-therapeutics-atacicept-autoimmune-kidney-disease\/\" rel=\"nofollow noopener\" target=\"_blank\">Vera Therapeutics<\/a>.<\/p>\n<p>All three companies have been racing to treat a disease that affects 330,000 people across the U.S. and Europe, according to Vertex\u2019s estimates, putting many at risk of developing end-stage renal disease. Analysts have projected Vertex\u2019s drug could eventually bring in $4 billion or more in annual sales.\u00a0<\/p>\n<p class=\"restricted-text\">STAT+ Exclusive Story<\/p>\n<p class=\"restricted-login\">Already have an account? <a href=\"https:\/\/www.statnews.com\/login\/\" data-stat-login=\"\" data-stat-paywall-cta=\"breaker login cta\" rel=\"nofollow noopener\" target=\"_blank\">Log in<\/a><\/p>\n<p>\t\t\t<img decoding=\"async\" class=\"restricted-content-breaker-bg\" src=\"https:\/\/www.newsbeep.com\/us\/wp-content\/uploads\/2025\/12\/1765280600_844_stat-plus-breaker-bg.png\" alt=\"STAT+\"\/><\/p>\n<p>\t\t\t\t\t<a href=\"https:\/\/www.statnews.com\/stat-plus\/\" rel=\"nofollow noopener\" target=\"_blank\"><br \/>\n\t\t\t\t\t\t<img decoding=\"async\" class=\"stat-plus-logo\" src=\"https:\/\/www.statnews.com\/wp-content\/themes\/stat\/images\/stat-plus-logo-white.svg\" alt=\"STAT+\"\/><br \/>\n\t\t\t\t\t<\/a><\/p>\n<p>\t\t\t\tThis article is exclusive to STAT+ subscribers<br \/>\n\t\t\t\tUnlock this article \u2014 plus daily coverage and analysis of the biotech sector \u2014 by subscribing to STAT+.<\/p>\n<p class=\"restricted-content-breaker-wrapper-cta mobile\">Already have an account? <a href=\"https:\/\/www.statnews.com\/login\/\" data-stat-login=\"\" data-stat-paywall-cta=\"breaker login cta mobile\" rel=\"nofollow noopener\" target=\"_blank\">Log in<\/a><\/p>\n<p>\t\t\t\t\t\tIndividual plans<\/p>\n<p>\t\t\t\t\t\tGroup plans<\/p>\n<p>\t\t\t\t<a href=\"https:\/\/www.statnews.com\/stat-plus\/\" class=\"stat-button view-all\" data-stat-paywall-cta=\"breaker view all plans\" aria-label=\"View All Plans\" rel=\"nofollow noopener\" target=\"_blank\">View All Plans<\/a><\/p>\n<p class=\"restricted-content-text\">\n\t\t\t\t\t\tTo read the rest of this story subscribe to STAT+.\t\t\t\t\t<\/p>\n<p>\t\t\t\t\t<a href=\"https:\/\/www.statnews.com\/stat-plus\/\" class=\"stat-button restricted-button\" data-stat-paywall-cta=\"breaker subscribe cta 1\" rel=\"nofollow noopener\" target=\"_blank\">Subscribe<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"Vertex said Monday that a drug it secured as part of a $4.9 billion acquisition successfully reduced by&hellip;\n","protected":false},"author":2,"featured_media":514909,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[27],"tags":[244,28,16347,247,248,118876],"class_list":["post-514908","post","type-post","status-publish","format-standard","has-post-thumbnail","category-business","tag-biotechnology","tag-business","tag-chronic-disease","tag-pharmaceuticals","tag-stat","tag-vertex"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/514908","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/comments?post=514908"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/514908\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media\/514909"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media?parent=514908"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/categories?post=514908"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/tags?post=514908"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}