{"id":519402,"date":"2026-03-12T16:12:11","date_gmt":"2026-03-12T16:12:11","guid":{"rendered":"https:\/\/www.newsbeep.com\/us\/519402\/"},"modified":"2026-03-12T16:12:11","modified_gmt":"2026-03-12T16:12:11","slug":"gene-conversion-empowers-natural-selection-in-a-clonal-fish-species","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us\/519402\/","title":{"rendered":"Gene conversion empowers natural selection in a clonal fish species"},"content":{"rendered":"<p class=\"c-article-references__text\" id=\"ref-CR1\">Speijer, D., Luke\u0161, J. &amp; Eli\u00e1\u0161, M. Sex is a ubiquitous, ancient, and inherent attribute of eukaryotic life. Proc. Natl Acad. Sci. USA 112, 8827\u20138834 (2015).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1073\/pnas.1501725112\" data-track-item_id=\"10.1073\/pnas.1501725112\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1073%2Fpnas.1501725112\" aria-label=\"Article reference 1\" data-doi=\"10.1073\/pnas.1501725112\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"ads reference\" data-track-action=\"ads reference\" href=\"http:\/\/adsabs.harvard.edu\/cgi-bin\/nph-data_query?link_type=ABSTRACT&amp;bibcode=2015PNAS..112.8827S\" aria-label=\"ADS reference 1\" target=\"_blank\">ADS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC2MXhtF2hsrfI\" aria-label=\"CAS reference 1\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4517231\" aria-label=\"PubMed Central reference 1\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 1\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Sex%20is%20a%20ubiquitous%2C%20ancient%2C%20and%20inherent%20attribute%20of%20eukaryotic%20life&amp;journal=Proc.%20Natl%20Acad.%20Sci.%20USA&amp;doi=10.1073%2Fpnas.1501725112&amp;volume=112&amp;pages=8827-8834&amp;publication_year=2015&amp;author=Speijer%2CD&amp;author=Luke%C5%A1%2CJ&amp;author=Eli%C3%A1%C5%A1%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR2\">Muller, H. J. Some genetic aspects of sex. Am. Nat. 66, 118\u2013138 (1932).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1086\/280418\" data-track-item_id=\"10.1086\/280418\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1086%2F280418\" aria-label=\"Article reference 2\" data-doi=\"10.1086\/280418\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 2\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Some%20genetic%20aspects%20of%20sex&amp;journal=Am.%20Nat.&amp;doi=10.1086%2F280418&amp;volume=66&amp;pages=118-138&amp;publication_year=1932&amp;author=Muller%2CHJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR3\">Muller, H. J. The relation of recombination to mutational advance. Mutat. Res. 106, 2\u20139 (1964).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1016\/0027-5107(64)90047-8\" data-track-item_id=\"10.1016\/0027-5107(64)90047-8\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1016%2F0027-5107%2864%2990047-8\" aria-label=\"Article reference 3\" data-doi=\"10.1016\/0027-5107(64)90047-8\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:STN:280:DyaF2M%2FgtVWiug%3D%3D\" aria-label=\"CAS reference 3\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 3\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20relation%20of%20recombination%20to%20mutational%20advance&amp;journal=Mutat.%20Res.&amp;doi=10.1016%2F0027-5107%2864%2990047-8&amp;volume=106&amp;pages=2-9&amp;publication_year=1964&amp;author=Muller%2CHJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR4\">Felsenstein, J. The evolutionary advantage of recombination. Genetics 78, 737\u2013756 (1974).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/genetics\/78.2.737\" data-track-item_id=\"10.1093\/genetics\/78.2.737\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fgenetics%2F78.2.737\" aria-label=\"Article reference 4\" data-doi=\"10.1093\/genetics\/78.2.737\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:STN:280:DyaE2M%2FpsVWrsQ%3D%3D\" aria-label=\"CAS reference 4\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1213231\" aria-label=\"PubMed Central reference 4\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 4\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20evolutionary%20advantage%20of%20recombination&amp;journal=Genetics&amp;doi=10.1093%2Fgenetics%2F78.2.737&amp;volume=78&amp;pages=737-756&amp;publication_year=1974&amp;author=Felsenstein%2CJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR5\">Quattro, J. M., Avise, J. C. &amp; Vrijenhoek, R. C. An ancient clonal lineage in the fish genus Poeciliopsis (Atheriniformes: Poeciliidae). Proc. Natl Acad. Sci. USA 89, 348\u2013352 (1992).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1073\/pnas.89.1.348\" data-track-item_id=\"10.1073\/pnas.89.1.348\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1073%2Fpnas.89.1.348\" aria-label=\"Article reference 5\" data-doi=\"10.1073\/pnas.89.1.348\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"ads reference\" data-track-action=\"ads reference\" href=\"http:\/\/adsabs.harvard.edu\/cgi-bin\/nph-data_query?link_type=ABSTRACT&amp;bibcode=1992PNAS...89..348Q\" aria-label=\"ADS reference 5\" target=\"_blank\">ADS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:STN:280:DC%2BD3MrmtFahtQ%3D%3D\" aria-label=\"CAS reference 5\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC48234\" aria-label=\"PubMed Central reference 5\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 5\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=An%20ancient%20clonal%20lineage%20in%20the%20fish%20genus%20Poeciliopsis%20%28Atheriniformes%3A%20Poeciliidae%29&amp;journal=Proc.%20Natl%20Acad.%20Sci.%20USA&amp;doi=10.1073%2Fpnas.89.1.348&amp;volume=89&amp;pages=348-352&amp;publication_year=1992&amp;author=Quattro%2CJM&amp;author=Avise%2CJC&amp;author=Vrijenhoek%2CRC\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR6\">Welch, M. D. &amp; Meselson, M. Evidence for the evolution of bdelloid rotifers without sexual reproduction or genetic exchange. Science 288, 1211\u20131215 (2000).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1126\/science.288.5469.1211\" data-track-item_id=\"10.1126\/science.288.5469.1211\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1126%2Fscience.288.5469.1211\" aria-label=\"Article reference 6\" data-doi=\"10.1126\/science.288.5469.1211\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"ads reference\" data-track-action=\"ads reference\" href=\"http:\/\/adsabs.harvard.edu\/cgi-bin\/nph-data_query?link_type=ABSTRACT&amp;bibcode=2000Sci...288.1211W\" aria-label=\"ADS reference 6\" target=\"_blank\">ADS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BD3cXjsFOqtbo%3D\" aria-label=\"CAS reference 6\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 6\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Evidence%20for%20the%20evolution%20of%20bdelloid%20rotifers%20without%20sexual%20reproduction%20or%20genetic%20exchange&amp;journal=Science&amp;doi=10.1126%2Fscience.288.5469.1211&amp;volume=288&amp;pages=1211-1215&amp;publication_year=2000&amp;author=Welch%2CMD&amp;author=Meselson%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR7\">Schwander, T., Henry, L. &amp; Crespi, B. J. Molecular evidence for ancient asexuality in timema stick insects. Curr. Biol. 21, 1129\u20131134 (2011).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1016\/j.cub.2011.05.026\" data-track-item_id=\"10.1016\/j.cub.2011.05.026\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1016%2Fj.cub.2011.05.026\" aria-label=\"Article reference 7\" data-doi=\"10.1016\/j.cub.2011.05.026\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC3MXoslaktbw%3D\" aria-label=\"CAS reference 7\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 7\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Molecular%20evidence%20for%20ancient%20asexuality%20in%20timema%20stick%20insects&amp;journal=Curr.%20Biol.&amp;doi=10.1016%2Fj.cub.2011.05.026&amp;volume=21&amp;pages=1129-1134&amp;publication_year=2011&amp;author=Schwander%2CT&amp;author=Henry%2CL&amp;author=Crespi%2CBJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR8\">Hubbs, C. L. &amp; Hubbs, L. C. Apparent parthenogenesis in nature, in a form of fish of hybrid origin. Science 76, 628\u2013630 (1932).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1126\/science.76.1983.628\" data-track-item_id=\"10.1126\/science.76.1983.628\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1126%2Fscience.76.1983.628\" aria-label=\"Article reference 8\" data-doi=\"10.1126\/science.76.1983.628\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"ads reference\" data-track-action=\"ads reference\" href=\"http:\/\/adsabs.harvard.edu\/cgi-bin\/nph-data_query?link_type=ABSTRACT&amp;bibcode=1932Sci....76..628H\" aria-label=\"ADS reference 8\" target=\"_blank\">ADS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:STN:280:DC%2BC3cvmsFOqsQ%3D%3D\" aria-label=\"CAS reference 8\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 8\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Apparent%20parthenogenesis%20in%20nature%2C%20in%20a%20form%20of%20fish%20of%20hybrid%20origin&amp;journal=Science&amp;doi=10.1126%2Fscience.76.1983.628&amp;volume=76&amp;pages=628-630&amp;publication_year=1932&amp;author=Hubbs%2CCL&amp;author=Hubbs%2CLC\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR9\">St\u00f6ck, M., Lampert, K. P., M\u00f6ller, D., Schlupp, I. &amp; Schartl, M. Monophyletic origin of multiple clonal lineages in an asexual fish (Poecilia formosa). Mol. Ecol. 19, 5204\u20135215 (2010).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1111\/j.1365-294X.2010.04869.x\" data-track-item_id=\"10.1111\/j.1365-294X.2010.04869.x\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1111%2Fj.1365-294X.2010.04869.x\" aria-label=\"Article reference 9\" data-doi=\"10.1111\/j.1365-294X.2010.04869.x\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 9\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Monophyletic%20origin%20of%20multiple%20clonal%20lineages%20in%20an%20asexual%20fish%20%28Poecilia%20formosa%29&amp;journal=Mol.%20Ecol.&amp;doi=10.1111%2Fj.1365-294X.2010.04869.x&amp;volume=19&amp;pages=5204-5215&amp;publication_year=2010&amp;author=St%C3%B6ck%2CM&amp;author=Lampert%2CKP&amp;author=M%C3%B6ller%2CD&amp;author=Schlupp%2CI&amp;author=Schartl%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR10\">Warren, W. C. et al. Clonal polymorphism and high heterozygosity in the celibate genome of the Amazon molly. Nat. Ecol. Evol. 2, 669\u2013679 (2018).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/s41559-018-0473-y\" data-track-item_id=\"10.1038\/s41559-018-0473-y\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fs41559-018-0473-y\" aria-label=\"Article reference 10\" data-doi=\"10.1038\/s41559-018-0473-y\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5866774\" aria-label=\"PubMed Central reference 10\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 10\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Clonal%20polymorphism%20and%20high%20heterozygosity%20in%20the%20celibate%20genome%20of%20the%20Amazon%20molly&amp;journal=Nat.%20Ecol.%20Evol.&amp;doi=10.1038%2Fs41559-018-0473-y&amp;volume=2&amp;pages=669-679&amp;publication_year=2018&amp;author=Warren%2CWC\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR11\">Smith, J. M. The Evolution of Sex (Cambridge Univ. Press, 1978).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR12\">Birky, C. W. Jr. Heterozygosity, heteromorphy, and phylogenetic trees in asexual eukaryotes. Genetics 144, 427\u2013437 (1996).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/genetics\/144.1.427\" data-track-item_id=\"10.1093\/genetics\/144.1.427\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fgenetics%2F144.1.427\" aria-label=\"Article reference 12\" data-doi=\"10.1093\/genetics\/144.1.427\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1207515\" aria-label=\"PubMed Central reference 12\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 12\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Heterozygosity%2C%20heteromorphy%2C%20and%20phylogenetic%20trees%20in%20asexual%20eukaryotes&amp;journal=Genetics&amp;doi=10.1093%2Fgenetics%2F144.1.427&amp;volume=144&amp;pages=427-437&amp;publication_year=1996&amp;author=Birky%2CCW\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR13\">Judson, O. P. &amp; Normark, B. B. Ancient asexual scandals. Trends Ecol. Evol. 11, 41\u201346 (1996).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1016\/0169-5347(96)81040-8\" data-track-item_id=\"10.1016\/0169-5347(96)81040-8\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1016%2F0169-5347%2896%2981040-8\" aria-label=\"Article reference 13\" data-doi=\"10.1016\/0169-5347(96)81040-8\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:STN:280:DC%2BC3M7itFersQ%3D%3D\" aria-label=\"CAS reference 13\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 13\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Ancient%20asexual%20scandals&amp;journal=Trends%20Ecol.%20Evol.&amp;doi=10.1016%2F0169-5347%2896%2981040-8&amp;volume=11&amp;pages=41-46&amp;publication_year=1996&amp;author=Judson%2COP&amp;author=Normark%2CBB\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR14\">Lynch, M., Conery, J. &amp; Burger, R. Mutation accumulation and the extinction of small populations. Am. Nat. 146, 489\u2013518 (1995).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1086\/285812\" data-track-item_id=\"10.1086\/285812\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1086%2F285812\" aria-label=\"Article reference 14\" data-doi=\"10.1086\/285812\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 14\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Mutation%20accumulation%20and%20the%20extinction%20of%20small%20populations&amp;journal=Am.%20Nat.&amp;doi=10.1086%2F285812&amp;volume=146&amp;pages=489-518&amp;publication_year=1995&amp;author=Lynch%2CM&amp;author=Conery%2CJ&amp;author=Burger%2CR\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR15\">Bell, G. The Masterpiece of Nature: Evolution and Genetics of Sexuality (Croom Helm, 1982).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR16\">Smith, J. M. in Group Selection (ed. Williams, G. C.) Ch. 9 (Routledge, 1971).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR17\">Williams, G. C. Sex and Evolution (Princeton Univ. Press, 1975).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR18\">Tree of Sex Consortium Tree of Sex: a database of sexual systems. Sci. Data 1, 140015 (2014).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/sdata.2014.15\" data-track-item_id=\"10.1038\/sdata.2014.15\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fsdata.2014.15\" aria-label=\"Article reference 18\" data-doi=\"10.1038\/sdata.2014.15\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 18\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Tree%20of%20Sex%3A%20a%20database%20of%20sexual%20systems&amp;journal=Sci.%20Data&amp;doi=10.1038%2Fsdata.2014.15&amp;volume=1&amp;publication_year=2014\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR19\">Lynch, M. &amp; Gabriel, W. Mutation load and the survival of small populations. Evolution 44, 1725\u20131737 (1990).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1111\/j.1558-5646.1990.tb05244.x\" data-track-item_id=\"10.1111\/j.1558-5646.1990.tb05244.x\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1111%2Fj.1558-5646.1990.tb05244.x\" aria-label=\"Article reference 19\" data-doi=\"10.1111\/j.1558-5646.1990.tb05244.x\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 19\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Mutation%20load%20and%20the%20survival%20of%20small%20populations&amp;journal=Evolution&amp;doi=10.1111%2Fj.1558-5646.1990.tb05244.x&amp;volume=44&amp;pages=1725-1737&amp;publication_year=1990&amp;author=Lynch%2CM&amp;author=Gabriel%2CW\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR20\">Jaron, K. S. et al. Genomic features of parthenogenetic animals. J. Hered. 112, 19\u201333 (2021).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/jhered\/esaa031\" data-track-item_id=\"10.1093\/jhered\/esaa031\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fjhered%2Fesaa031\" aria-label=\"Article reference 20\" data-doi=\"10.1093\/jhered\/esaa031\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3MXitVOrsbjM\" aria-label=\"CAS reference 20\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7953838\" aria-label=\"PubMed Central reference 20\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 20\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Genomic%20features%20of%20parthenogenetic%20animals&amp;journal=J.%20Hered.&amp;doi=10.1093%2Fjhered%2Fesaa031&amp;volume=112&amp;pages=19-33&amp;publication_year=2021&amp;author=Jaron%2CKS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR21\">Dawley, R. M. &amp; Bogart, J. P. Evolution and Ecology of Unisexual Vertebrates (New York State Museum, 1989).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR22\">Avise, J. C. Clonality: The Genetics, Ecology, and Evolution of Sexual Abstinence in Vertebrate Animals (Oxford Univ. Press, 2008).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR23\">Barley, A. J., Nieto-Montes de Oca, A., Manr\u00edquez-Mor\u00e1n, N. L. &amp; Thomson, R. C. The evolutionary network of whiptail lizards reveals predictable outcomes of hybridization. Science 377, 773\u2013777 (2022).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1126\/science.abn1593\" data-track-item_id=\"10.1126\/science.abn1593\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1126%2Fscience.abn1593\" aria-label=\"Article reference 23\" data-doi=\"10.1126\/science.abn1593\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"ads reference\" data-track-action=\"ads reference\" href=\"http:\/\/adsabs.harvard.edu\/cgi-bin\/nph-data_query?link_type=ABSTRACT&amp;bibcode=2022Sci...377..773B\" aria-label=\"ADS reference 23\" target=\"_blank\">ADS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB38Xit1WhtrnE\" aria-label=\"CAS reference 23\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 23\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20evolutionary%20network%20of%20whiptail%20lizards%20reveals%20predictable%20outcomes%20of%20hybridization&amp;journal=Science&amp;doi=10.1126%2Fscience.abn1593&amp;volume=377&amp;pages=773-777&amp;publication_year=2022&amp;author=Barley%2CAJ&amp;author=Nieto-Montes%20de%20Oca%2CA&amp;author=Manr%C3%ADquez-Mor%C3%A1n%2CNL&amp;author=Thomson%2CRC\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR24\">Avise, J. C., Trexler, J. C., Travis, J. &amp; Nelson, W. S. Poecilia mexicana is the recent female parent of the unisexual fish P. formosa. Evolution 45, 1530\u20131533 (1991).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1111\/j.1558-5646.1991.tb02657.x\" data-track-item_id=\"10.1111\/j.1558-5646.1991.tb02657.x\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1111%2Fj.1558-5646.1991.tb02657.x\" aria-label=\"Article reference 24\" data-doi=\"10.1111\/j.1558-5646.1991.tb02657.x\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 24\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Poecilia%20mexicana%20is%20the%20recent%20female%20parent%20of%20the%20unisexual%20fish%20P.%20formosa&amp;journal=Evolution&amp;doi=10.1111%2Fj.1558-5646.1991.tb02657.x&amp;volume=45&amp;pages=1530-1533&amp;publication_year=1991&amp;author=Avise%2CJC&amp;author=Trexler%2CJC&amp;author=Travis%2CJ&amp;author=Nelson%2CWS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR25\">Schartl, M., Wilde, B., Schlupp, I. &amp; Parzefall, J. Evolutionary origin of a parthenoform, the Amazon molly Poecilia formosa, on the basis of a molecular genealogy. Evolution 49, 827 (1995).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DyaK28XktlyisA%3D%3D\" aria-label=\"CAS reference 25\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 25\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Evolutionary%20origin%20of%20a%20parthenoform%2C%20the%20Amazon%20molly%20Poecilia%20formosa%2C%20on%20the%20basis%20of%20a%20molecular%20genealogy&amp;journal=Evolution&amp;volume=49&amp;publication_year=1995&amp;author=Schartl%2CM&amp;author=Wilde%2CB&amp;author=Schlupp%2CI&amp;author=Parzefall%2CJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR26\">Turner, B. J. The evolutionary genetics of a unisexual fish, Poecilia formosa. Prog. Clin. Biol. Res. 96, 265\u2013305 (1982).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:STN:280:DyaL3s%2FptFamsw%3D%3D\" aria-label=\"CAS reference 26\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 26\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20evolutionary%20genetics%20of%20a%20unisexual%20fish%2C%20Poecilia%20formosa&amp;journal=Prog.%20Clin.%20Biol.%20Res.&amp;volume=96&amp;pages=265-305&amp;publication_year=1982&amp;author=Turner%2CBJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR27\">Costa, G. C. &amp; Schlupp, I. Placing the hybrid origin of the asexual Amazon molly (Poecilia formosa) based on historical climate data. Biol. J. Linn. Soc. Lond. 129, 835\u2013843 (2020).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/biolinnean\/blaa010\" data-track-item_id=\"10.1093\/biolinnean\/blaa010\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fbiolinnean%2Fblaa010\" aria-label=\"Article reference 27\" data-doi=\"10.1093\/biolinnean\/blaa010\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 27\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Placing%20the%20hybrid%20origin%20of%20the%20asexual%20Amazon%20molly%20%28Poecilia%20formosa%29%20based%20on%20historical%20climate%20data&amp;journal=Biol.%20J.%20Linn.%20Soc.%20Lond.&amp;doi=10.1093%2Fbiolinnean%2Fblaa010&amp;volume=129&amp;pages=835-843&amp;publication_year=2020&amp;author=Costa%2CGC&amp;author=Schlupp%2CI\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR28\">Costa, G. C. &amp; Schlupp, I. Biogeography of the Amazon molly: ecological niche and range limits of an asexual hybrid species. Glob. Ecol. Biogeogr. 19, 442\u2013451 (2010).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1111\/j.1466-8238.2010.00546.x\" data-track-item_id=\"10.1111\/j.1466-8238.2010.00546.x\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1111%2Fj.1466-8238.2010.00546.x\" aria-label=\"Article reference 28\" data-doi=\"10.1111\/j.1466-8238.2010.00546.x\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 28\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Biogeography%20of%20the%20Amazon%20molly%3A%20ecological%20niche%20and%20range%20limits%20of%20an%20asexual%20hybrid%20species&amp;journal=Glob.%20Ecol.%20Biogeogr.&amp;doi=10.1111%2Fj.1466-8238.2010.00546.x&amp;volume=19&amp;pages=442-451&amp;publication_year=2010&amp;author=Costa%2CGC&amp;author=Schlupp%2CI\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR29\">Dedukh, D. et al. Achiasmatic meiosis in the unisexual Amazon molly, Poecilia formosa. Chromosome Res. 30, 443\u2013457 (2022).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1007\/s10577-022-09708-2\" data-track-item_id=\"10.1007\/s10577-022-09708-2\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1007\/s10577-022-09708-2\" aria-label=\"Article reference 29\" data-doi=\"10.1007\/s10577-022-09708-2\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB38XjtVekur3F\" aria-label=\"CAS reference 29\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9771850\" aria-label=\"PubMed Central reference 29\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 29\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Achiasmatic%20meiosis%20in%20the%20unisexual%20Amazon%20molly%2C%20Poecilia%20formosa&amp;journal=Chromosome%20Res.&amp;doi=10.1007%2Fs10577-022-09708-2&amp;volume=30&amp;pages=443-457&amp;publication_year=2022&amp;author=Dedukh%2CD\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR30\">Kallman, K. D. Population genetics of the gynogenetic teleost, Mollienesia formosa (Girard). Evolution 16, 497\u2013504 (1962).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1111\/j.1558-5646.1962.tb03239.x\" data-track-item_id=\"10.1111\/j.1558-5646.1962.tb03239.x\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1111%2Fj.1558-5646.1962.tb03239.x\" aria-label=\"Article reference 30\" data-doi=\"10.1111\/j.1558-5646.1962.tb03239.x\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 30\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Population%20genetics%20of%20the%20gynogenetic%20teleost%2C%20Mollienesia%20formosa%20%28Girard%29&amp;journal=Evolution&amp;doi=10.1111%2Fj.1558-5646.1962.tb03239.x&amp;volume=16&amp;pages=497-504&amp;publication_year=1962&amp;author=Kallman%2CKD\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR31\">Turner, B. J., Elder, J. F. Jr, Laughlin, T. F. &amp; Davis, W. P. Genetic variation in clonal vertebrates detected by simple-sequence DNA fingerprinting. Proc. Natl Acad. Sci. USA 87, 5653\u20135657 (1990).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1073\/pnas.87.15.5653\" data-track-item_id=\"10.1073\/pnas.87.15.5653\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1073%2Fpnas.87.15.5653\" aria-label=\"Article reference 31\" data-doi=\"10.1073\/pnas.87.15.5653\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"ads reference\" data-track-action=\"ads reference\" href=\"http:\/\/adsabs.harvard.edu\/cgi-bin\/nph-data_query?link_type=ABSTRACT&amp;bibcode=1990PNAS...87.5653T\" aria-label=\"ADS reference 31\" target=\"_blank\">ADS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DyaK3cXlsVKmsr8%3D\" aria-label=\"CAS reference 31\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC54385\" aria-label=\"PubMed Central reference 31\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 31\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Genetic%20variation%20in%20clonal%20vertebrates%20detected%20by%20simple-sequence%20DNA%20fingerprinting&amp;journal=Proc.%20Natl%20Acad.%20Sci.%20USA&amp;doi=10.1073%2Fpnas.87.15.5653&amp;volume=87&amp;pages=5653-5657&amp;publication_year=1990&amp;author=Turner%2CBJ&amp;author=Elder%2CJF&amp;author=Laughlin%2CTF&amp;author=Davis%2CWP\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR32\">Schartl, M. et al. On the stability of dispensable constituents of the eukaryotic genome: stability of coding sequences versus truly hypervariable sequences in a clonal vertebrate, the amazon molly, Poecilia formosa. Proc. Natl Acad. Sci. USA. 88, 8759\u20138763 (1991).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1073\/pnas.88.19.8759\" data-track-item_id=\"10.1073\/pnas.88.19.8759\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1073%2Fpnas.88.19.8759\" aria-label=\"Article reference 32\" data-doi=\"10.1073\/pnas.88.19.8759\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"ads reference\" data-track-action=\"ads reference\" href=\"http:\/\/adsabs.harvard.edu\/cgi-bin\/nph-data_query?link_type=ABSTRACT&amp;bibcode=1991PNAS...88.8759S\" aria-label=\"ADS reference 32\" target=\"_blank\">ADS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DyaK38XhsFOl\" aria-label=\"CAS reference 32\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC52589\" aria-label=\"PubMed Central reference 32\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 32\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=On%20the%20stability%20of%20dispensable%20constituents%20of%20the%20eukaryotic%20genome%3A%20stability%20of%20coding%20sequences%20versus%20truly%20hypervariable%20sequences%20in%20a%20clonal%20vertebrate%2C%20the%20amazon%20molly%2C%20Poecilia%20formosa&amp;journal=Proc.%20Natl%20Acad.%20Sci.%20USA.&amp;doi=10.1073%2Fpnas.88.19.8759&amp;volume=88&amp;pages=8759-8763&amp;publication_year=1991&amp;author=Schartl%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR33\">Loewe, L. &amp; Lamatsch, D. K. Quantifying the threat of extinction from Muller\u2019s ratchet in the diploid Amazon molly (Poecilia formosa). BMC Evol. Biol. 8, 88 (2008).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1186\/1471-2148-8-88\" data-track-item_id=\"10.1186\/1471-2148-8-88\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1186\/1471-2148-8-88\" aria-label=\"Article reference 33\" data-doi=\"10.1186\/1471-2148-8-88\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2292145\" aria-label=\"PubMed Central reference 33\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 33\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Quantifying%20the%20threat%20of%20extinction%20from%20Muller%E2%80%99s%20ratchet%20in%20the%20diploid%20Amazon%20molly%20%28Poecilia%20formosa%29&amp;journal=BMC%20Evol.%20Biol.&amp;doi=10.1186%2F1471-2148-8-88&amp;volume=8&amp;publication_year=2008&amp;author=Loewe%2CL&amp;author=Lamatsch%2CDK\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR34\">Koren, S. et al. De novo assembly of haplotype-resolved genomes with trio binning. Nat. Biotechnol. 36, 1174\u20131182 (2018).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/nbt.4277\" data-track-item_id=\"10.1038\/nbt.4277\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fnbt.4277\" aria-label=\"Article reference 34\" data-doi=\"10.1038\/nbt.4277\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"ads reference\" data-track-action=\"ads reference\" href=\"http:\/\/adsabs.harvard.edu\/cgi-bin\/nph-data_query?link_type=ABSTRACT&amp;bibcode=2018NatBi..36.1174K\" aria-label=\"ADS reference 34\" target=\"_blank\">ADS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC1cXhvFKis7jP\" aria-label=\"CAS reference 34\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 34\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=De%20novo%20assembly%20of%20haplotype-resolved%20genomes%20with%20trio%20binning&amp;journal=Nat.%20Biotechnol.&amp;doi=10.1038%2Fnbt.4277&amp;volume=36&amp;pages=1174-1182&amp;publication_year=2018&amp;author=Koren%2CS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR35\">Rice, E. S. et al. Continuous chromosome-scale haplotypes assembled from a single interspecies F1 hybrid of yak and cattle. GigaScience 9, giaa029 (2020).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/gigascience\/giaa029\" data-track-item_id=\"10.1093\/gigascience\/giaa029\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fgigascience%2Fgiaa029\" aria-label=\"Article reference 35\" data-doi=\"10.1093\/gigascience\/giaa029\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7118895\" aria-label=\"PubMed Central reference 35\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 35\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Continuous%20chromosome-scale%20haplotypes%20assembled%20from%20a%20single%20interspecies%20F1%20hybrid%20of%20yak%20and%20cattle&amp;journal=GigaScience&amp;doi=10.1093%2Fgigascience%2Fgiaa029&amp;volume=9&amp;publication_year=2020&amp;author=Rice%2CES\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR36\">Moran, N. A. Accelerated evolution and Muller\u2019s rachet in endosymbiotic bacteria. Proc. Natl Acad. Sci. USA 93, 2873\u20132878 (1996).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1073\/pnas.93.7.2873\" data-track-item_id=\"10.1073\/pnas.93.7.2873\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1073%2Fpnas.93.7.2873\" aria-label=\"Article reference 36\" data-doi=\"10.1073\/pnas.93.7.2873\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"ads reference\" data-track-action=\"ads reference\" href=\"http:\/\/adsabs.harvard.edu\/cgi-bin\/nph-data_query?link_type=ABSTRACT&amp;bibcode=1996PNAS...93.2873M\" aria-label=\"ADS reference 36\" target=\"_blank\">ADS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DyaK28XitVCit78%3D\" aria-label=\"CAS reference 36\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC39726\" aria-label=\"PubMed Central reference 36\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 36\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Accelerated%20evolution%20and%20Muller%E2%80%99s%20rachet%20in%20endosymbiotic%20bacteria&amp;journal=Proc.%20Natl%20Acad.%20Sci.%20USA&amp;doi=10.1073%2Fpnas.93.7.2873&amp;volume=93&amp;pages=2873-2878&amp;publication_year=1996&amp;author=Moran%2CNA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR37\">Nesta, A. V., Tafur, D. &amp; Beck, C. R. Hotspots of human mutation. Trends Genet. 37, 717\u2013729 (2021).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1016\/j.tig.2020.10.003\" data-track-item_id=\"10.1016\/j.tig.2020.10.003\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1016%2Fj.tig.2020.10.003\" aria-label=\"Article reference 37\" data-doi=\"10.1016\/j.tig.2020.10.003\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3cXitFSgu7bI\" aria-label=\"CAS reference 37\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 37\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Hotspots%20of%20human%20mutation&amp;journal=Trends%20Genet.&amp;doi=10.1016%2Fj.tig.2020.10.003&amp;volume=37&amp;pages=717-729&amp;publication_year=2021&amp;author=Nesta%2CAV&amp;author=Tafur%2CD&amp;author=Beck%2CCR\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR38\">Gonzalez-Perez, A., Sabarinathan, R. &amp; Lopez-Bigas, N. Local determinants of the mutational landscape of the human genome. Cell 177, 101\u2013114 (2019).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1016\/j.cell.2019.02.051\" data-track-item_id=\"10.1016\/j.cell.2019.02.051\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1016%2Fj.cell.2019.02.051\" aria-label=\"Article reference 38\" data-doi=\"10.1016\/j.cell.2019.02.051\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC1MXlvVWgtLY%3D\" aria-label=\"CAS reference 38\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 38\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Local%20determinants%20of%20the%20mutational%20landscape%20of%20the%20human%20genome&amp;journal=Cell&amp;doi=10.1016%2Fj.cell.2019.02.051&amp;volume=177&amp;pages=101-114&amp;publication_year=2019&amp;author=Gonzalez-Perez%2CA&amp;author=Sabarinathan%2CR&amp;author=Lopez-Bigas%2CN\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR39\">Omilian, A. R., Cristescu, M. E. A., Dudycha, J. L. &amp; Lynch, M. Ameiotic recombination in asexual lineages of Daphnia. Proc. Natl Acad. Sci. USA 103, 18638\u201318643 (2006).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1073\/pnas.0606435103\" data-track-item_id=\"10.1073\/pnas.0606435103\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1073%2Fpnas.0606435103\" aria-label=\"Article reference 39\" data-doi=\"10.1073\/pnas.0606435103\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"ads reference\" data-track-action=\"ads reference\" href=\"http:\/\/adsabs.harvard.edu\/cgi-bin\/nph-data_query?link_type=ABSTRACT&amp;bibcode=2006PNAS..10318638O\" aria-label=\"ADS reference 39\" target=\"_blank\">ADS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BD28Xhtlahtr3F\" aria-label=\"CAS reference 39\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1693715\" aria-label=\"PubMed Central reference 39\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 39\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Ameiotic%20recombination%20in%20asexual%20lineages%20of%20Daphnia&amp;journal=Proc.%20Natl%20Acad.%20Sci.%20USA&amp;doi=10.1073%2Fpnas.0606435103&amp;volume=103&amp;pages=18638-18643&amp;publication_year=2006&amp;author=Omilian%2CAR&amp;author=Cristescu%2CMEA&amp;author=Dudycha%2CJL&amp;author=Lynch%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR40\">Weir, W. et al. Population genomics reveals the origin and asexual evolution of human infective trypanosomes. eLife 5, e11473 (2016).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.7554\/eLife.11473\" data-track-item_id=\"10.7554\/eLife.11473\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.7554%2FeLife.11473\" aria-label=\"Article reference 40\" data-doi=\"10.7554\/eLife.11473\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4739771\" aria-label=\"PubMed Central reference 40\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 40\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Population%20genomics%20reveals%20the%20origin%20and%20asexual%20evolution%20of%20human%20infective%20trypanosomes&amp;journal=eLife&amp;doi=10.7554%2FeLife.11473&amp;volume=5&amp;publication_year=2016&amp;author=Weir%2CW\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR41\">Brandt, A. et al. Haplotype divergence supports long-term asexuality in the oribatid mite Oppiella nova. Proc. Natl Acad. Sci. USA 118, e2101485118 (2021).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1073\/pnas.2101485118\" data-track-item_id=\"10.1073\/pnas.2101485118\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1073%2Fpnas.2101485118\" aria-label=\"Article reference 41\" data-doi=\"10.1073\/pnas.2101485118\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3MXisVGqu7nL\" aria-label=\"CAS reference 41\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8463897\" aria-label=\"PubMed Central reference 41\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 41\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Haplotype%20divergence%20supports%20long-term%20asexuality%20in%20the%20oribatid%20mite%20Oppiella%20nova&amp;journal=Proc.%20Natl%20Acad.%20Sci.%20USA&amp;doi=10.1073%2Fpnas.2101485118&amp;volume=118&amp;publication_year=2021&amp;author=Brandt%2CA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR42\">Tubbs, A. et al. Dual roles of poly(dA:dT) tracts in replication initiation and fork collapse. Cell 174, 1127\u20131142.e19 (2018).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1016\/j.cell.2018.07.011\" data-track-item_id=\"10.1016\/j.cell.2018.07.011\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1016%2Fj.cell.2018.07.011\" aria-label=\"Article reference 42\" data-doi=\"10.1016\/j.cell.2018.07.011\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC1cXhsVers7nJ\" aria-label=\"CAS reference 42\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6591735\" aria-label=\"PubMed Central reference 42\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 42\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Dual%20roles%20of%20poly%28dA%3AdT%29%20tracts%20in%20replication%20initiation%20and%20fork%20collapse&amp;journal=Cell&amp;doi=10.1016%2Fj.cell.2018.07.011&amp;volume=174&amp;pages=1127-1142.e19&amp;publication_year=2018&amp;author=Tubbs%2CA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR43\">Stewart, J. A. et al. Noncanonical outcomes of break-induced replication produce complex, extremely long-tract gene conversion events in yeast. G3 11, jkab245 (2021).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/g3journal\/jkab245\" data-track-item_id=\"10.1093\/g3journal\/jkab245\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fg3journal%2Fjkab245\" aria-label=\"Article reference 43\" data-doi=\"10.1093\/g3journal\/jkab245\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8473981\" aria-label=\"PubMed Central reference 43\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 43\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Noncanonical%20outcomes%20of%20break-induced%20replication%20produce%20complex%2C%20extremely%20long-tract%20gene%20conversion%20events%20in%20yeast&amp;journal=G3&amp;doi=10.1093%2Fg3journal%2Fjkab245&amp;volume=11&amp;publication_year=2021&amp;author=Stewart%2CJA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR44\">Chen, J.-M., Cooper, D. N., Chuzhanova, N., F\u00e9rec, C. &amp; Patrinos, G. P. Gene conversion: mechanisms, evolution and human disease. Nat. Rev. Genet. 8, 762\u2013775 (2007).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/nrg2193\" data-track-item_id=\"10.1038\/nrg2193\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fnrg2193\" aria-label=\"Article reference 44\" data-doi=\"10.1038\/nrg2193\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BD2sXhtVCrsbzE\" aria-label=\"CAS reference 44\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 44\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Gene%20conversion%3A%20mechanisms%2C%20evolution%20and%20human%20disease&amp;journal=Nat.%20Rev.%20Genet.&amp;doi=10.1038%2Fnrg2193&amp;volume=8&amp;pages=762-775&amp;publication_year=2007&amp;author=Chen%2CJ-M&amp;author=Cooper%2CDN&amp;author=Chuzhanova%2CN&amp;author=F%C3%A9rec%2CC&amp;author=Patrinos%2CGP\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR45\">Zeng, K., Fu, Y.-X., Shi, S. &amp; Wu, C.-I. Statistical tests for detecting positive selection by utilizing high-frequency variants. Genetics 174, 1431\u20131439 (2006).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1534\/genetics.106.061432\" data-track-item_id=\"10.1534\/genetics.106.061432\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1534%2Fgenetics.106.061432\" aria-label=\"Article reference 45\" data-doi=\"10.1534\/genetics.106.061432\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1667063\" aria-label=\"PubMed Central reference 45\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 45\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Statistical%20tests%20for%20detecting%20positive%20selection%20by%20utilizing%20high-frequency%20variants&amp;journal=Genetics&amp;doi=10.1534%2Fgenetics.106.061432&amp;volume=174&amp;pages=1431-1439&amp;publication_year=2006&amp;author=Zeng%2CK&amp;author=Fu%2CY-X&amp;author=Shi%2CS&amp;author=Wu%2CC-I\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR46\">Mikocziova, I., Greiff, V. &amp; Sollid, L. M. Immunoglobulin germline gene variation and its impact on human disease. Genes Immun. 22, 205\u2013217 (2021).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/s41435-021-00145-5\" data-track-item_id=\"10.1038\/s41435-021-00145-5\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fs41435-021-00145-5\" aria-label=\"Article reference 46\" data-doi=\"10.1038\/s41435-021-00145-5\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3MXhsFaitrnL\" aria-label=\"CAS reference 46\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8234759\" aria-label=\"PubMed Central reference 46\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 46\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Immunoglobulin%20germline%20gene%20variation%20and%20its%20impact%20on%20human%20disease&amp;journal=Genes%20Immun.&amp;doi=10.1038%2Fs41435-021-00145-5&amp;volume=22&amp;pages=205-217&amp;publication_year=2021&amp;author=Mikocziova%2CI&amp;author=Greiff%2CV&amp;author=Sollid%2CLM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR47\">Kravitz, S. N. et al. Random allelic expression in the adult human body. Cell Rep. 42, 111945 (2023).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1016\/j.celrep.2022.111945\" data-track-item_id=\"10.1016\/j.celrep.2022.111945\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1016%2Fj.celrep.2022.111945\" aria-label=\"Article reference 47\" data-doi=\"10.1016\/j.celrep.2022.111945\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3sXivVOlsw%3D%3D\" aria-label=\"CAS reference 47\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10484211\" aria-label=\"PubMed Central reference 47\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 47\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Random%20allelic%20expression%20in%20the%20adult%20human%20body&amp;journal=Cell%20Rep.&amp;doi=10.1016%2Fj.celrep.2022.111945&amp;volume=42&amp;publication_year=2023&amp;author=Kravitz%2CSN\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR48\">Schaefer, N. K., Shapiro, B. &amp; Green, R. E. An ancestral recombination graph of human, Neanderthal, and Denisovan genomes. Sci. Adv. 7, eabc0776 (2021).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1126\/sciadv.abc0776\" data-track-item_id=\"10.1126\/sciadv.abc0776\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1126%2Fsciadv.abc0776\" aria-label=\"Article reference 48\" data-doi=\"10.1126\/sciadv.abc0776\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"ads reference\" data-track-action=\"ads reference\" href=\"http:\/\/adsabs.harvard.edu\/cgi-bin\/nph-data_query?link_type=ABSTRACT&amp;bibcode=2021SciA....7..776S\" aria-label=\"ADS reference 48\" target=\"_blank\">ADS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3MXitVGkur7J\" aria-label=\"CAS reference 48\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8284891\" aria-label=\"PubMed Central reference 48\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 48\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=An%20ancestral%20recombination%20graph%20of%20human%2C%20Neanderthal%2C%20and%20Denisovan%20genomes&amp;journal=Sci.%20Adv.&amp;doi=10.1126%2Fsciadv.abc0776&amp;volume=7&amp;publication_year=2021&amp;author=Schaefer%2CNK&amp;author=Shapiro%2CB&amp;author=Green%2CRE\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR49\">Johnson, N. A. &amp; Porter, A. H. Rapid speciation via parallel, directional selection on regulatory genetic pathways. J. Theor. Biol. 205, 527\u2013542 (2000).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1006\/jtbi.2000.2070\" data-track-item_id=\"10.1006\/jtbi.2000.2070\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1006%2Fjtbi.2000.2070\" aria-label=\"Article reference 49\" data-doi=\"10.1006\/jtbi.2000.2070\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"ads reference\" data-track-action=\"ads reference\" href=\"http:\/\/adsabs.harvard.edu\/cgi-bin\/nph-data_query?link_type=ABSTRACT&amp;bibcode=2000JThBi.205..527J\" aria-label=\"ADS reference 49\" target=\"_blank\">ADS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BD3cXlsVSku7k%3D\" aria-label=\"CAS reference 49\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 49\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Rapid%20speciation%20via%20parallel%2C%20directional%20selection%20on%20regulatory%20genetic%20pathways&amp;journal=J.%20Theor.%20Biol.&amp;doi=10.1006%2Fjtbi.2000.2070&amp;volume=205&amp;pages=527-542&amp;publication_year=2000&amp;author=Johnson%2CNA&amp;author=Porter%2CAH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR50\">Go, A., Alhazmi, D. &amp; Civetta, A. Altered expression of cell adhesion genes and hybrid male sterility between subspecies of Drosophila pseudoobscura. Genome 62, 657\u2013663 (2019).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1139\/gen-2019-0066\" data-track-item_id=\"10.1139\/gen-2019-0066\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1139%2Fgen-2019-0066\" aria-label=\"Article reference 50\" data-doi=\"10.1139\/gen-2019-0066\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC1MXhs1SitrbF\" aria-label=\"CAS reference 50\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 50\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Altered%20expression%20of%20cell%20adhesion%20genes%20and%20hybrid%20male%20sterility%20between%20subspecies%20of%20Drosophila%20pseudoobscura&amp;journal=Genome&amp;doi=10.1139%2Fgen-2019-0066&amp;volume=62&amp;pages=657-663&amp;publication_year=2019&amp;author=Go%2CA&amp;author=Alhazmi%2CD&amp;author=Civetta%2CA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR51\">Cheng, H., Concepcion, G. T., Feng, X., Zhang, H. &amp; Li, H. Haplotype-resolved de novo assembly using phased assembly graphs with hifiasm. Nat. Methods 18, 170\u2013175 (2021).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/s41592-020-01056-5\" data-track-item_id=\"10.1038\/s41592-020-01056-5\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fs41592-020-01056-5\" aria-label=\"Article reference 51\" data-doi=\"10.1038\/s41592-020-01056-5\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3MXis1OntL0%3D\" aria-label=\"CAS reference 51\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7961889\" aria-label=\"PubMed Central reference 51\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 51\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Haplotype-resolved%20de%20novo%20assembly%20using%20phased%20assembly%20graphs%20with%20hifiasm&amp;journal=Nat.%20Methods&amp;doi=10.1038%2Fs41592-020-01056-5&amp;volume=18&amp;pages=170-175&amp;publication_year=2021&amp;author=Cheng%2CH&amp;author=Concepcion%2CGT&amp;author=Feng%2CX&amp;author=Zhang%2CH&amp;author=Li%2CH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR52\">Rice, E. S. Trio_binning: programs implementing the trio-binning genome assembly method. Github <a href=\"https:\/\/github.com\/esrice\/trio_binning\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"https:\/\/github.com\/esrice\/trio_binning\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/github.com\/esrice\/trio_binning<\/a> (2022).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR53\">Kokot, M., Dlugosz, M. &amp; Deorowicz, S. KMC 3: counting and manipulating k-mer statistics. Bioinformatics 33, 2759\u20132761 (2017).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/bioinformatics\/btx304\" data-track-item_id=\"10.1093\/bioinformatics\/btx304\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fbioinformatics%2Fbtx304\" aria-label=\"Article reference 53\" data-doi=\"10.1093\/bioinformatics\/btx304\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC1cXitFOhtr3M\" aria-label=\"CAS reference 53\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 53\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=KMC%203%3A%20counting%20and%20manipulating%20k-mer%20statistics&amp;journal=Bioinformatics&amp;doi=10.1093%2Fbioinformatics%2Fbtx304&amp;volume=33&amp;pages=2759-2761&amp;publication_year=2017&amp;author=Kokot%2CM&amp;author=Dlugosz%2CM&amp;author=Deorowicz%2CS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR54\">Li, H. Minimap2: pairwise alignment for nucleotide sequences. Bioinformatics 34, 3094\u20133100 (2018).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/bioinformatics\/bty191\" data-track-item_id=\"10.1093\/bioinformatics\/bty191\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fbioinformatics%2Fbty191\" aria-label=\"Article reference 54\" data-doi=\"10.1093\/bioinformatics\/bty191\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC1MXhtVamu73J\" aria-label=\"CAS reference 54\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6137996\" aria-label=\"PubMed Central reference 54\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 54\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Minimap2%3A%20pairwise%20alignment%20for%20nucleotide%20sequences&amp;journal=Bioinformatics&amp;doi=10.1093%2Fbioinformatics%2Fbty191&amp;volume=34&amp;pages=3094-3100&amp;publication_year=2018&amp;author=Li%2CH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR55\">Di Tommaso, P. et al. Nextflow enables reproducible computational workflows. Nat. Biotechnol. 35, 316\u2013319 (2017).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/nbt.3820\" data-track-item_id=\"10.1038\/nbt.3820\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fnbt.3820\" aria-label=\"Article reference 55\" data-doi=\"10.1038\/nbt.3820\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 55\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Nextflow%20enables%20reproducible%20computational%20workflows&amp;journal=Nat.%20Biotechnol.&amp;doi=10.1038%2Fnbt.3820&amp;volume=35&amp;pages=316-319&amp;publication_year=2017&amp;author=Tommaso%2CP\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR56\">Rice, E. S. hic-scaffolding-nf: nextflow pipeline for scaffolding genome assemblies with Hi-C reads. Github <a href=\"https:\/\/github.com\/WarrenLab\/hic-scaffolding-nf\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"https:\/\/github.com\/WarrenLab\/hic-scaffolding-nf\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/github.com\/WarrenLab\/hic-scaffolding-nf<\/a> (2022).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR57\">Zhang, H. et al. Fast alignment and preprocessing of chromatin profiles with Chromap. Nat. Commun. 12, 6566 (2021).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/s41467-021-26865-w\" data-track-item_id=\"10.1038\/s41467-021-26865-w\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fs41467-021-26865-w\" aria-label=\"Article reference 57\" data-doi=\"10.1038\/s41467-021-26865-w\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"ads reference\" data-track-action=\"ads reference\" href=\"http:\/\/adsabs.harvard.edu\/cgi-bin\/nph-data_query?link_type=ABSTRACT&amp;bibcode=2021NatCo..12.6566Z\" aria-label=\"ADS reference 57\" target=\"_blank\">ADS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3MXisVOqtbfO\" aria-label=\"CAS reference 57\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8589834\" aria-label=\"PubMed Central reference 57\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 57\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Fast%20alignment%20and%20preprocessing%20of%20chromatin%20profiles%20with%20Chromap&amp;journal=Nat.%20Commun.&amp;doi=10.1038%2Fs41467-021-26865-w&amp;volume=12&amp;publication_year=2021&amp;author=Zhang%2CH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR58\">Zhou, C., McCarthy, S. A. &amp; Durbin, R. YaHS: yet another Hi-C scaffolding tool. Bioinformatics 39, btac808 (2023).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/bioinformatics\/btac808\" data-track-item_id=\"10.1093\/bioinformatics\/btac808\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fbioinformatics%2Fbtac808\" aria-label=\"Article reference 58\" data-doi=\"10.1093\/bioinformatics\/btac808\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3sXhsFKisLbN\" aria-label=\"CAS reference 58\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9848053\" aria-label=\"PubMed Central reference 58\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 58\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=YaHS%3A%20yet%20another%20Hi-C%20scaffolding%20tool&amp;journal=Bioinformatics&amp;doi=10.1093%2Fbioinformatics%2Fbtac808&amp;volume=39&amp;publication_year=2023&amp;author=Zhou%2CC&amp;author=McCarthy%2CSA&amp;author=Durbin%2CR\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR59\">Dudchenko, O. et al. The Juicebox Assembly Tools module facilitates de novo assembly of mammalian genomes with chromosome-length scaffolds for under $1000. Preprint at bioRxiv <a href=\"https:\/\/doi.org\/10.1101\/254797\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1101\/254797\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1101\/254797<\/a> (2018).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR60\">Lu, Y. et al. High resolution genomes of multiple Xiphophorus species provide new insights into microevolution, hybrid incompatibility, and epistasis. Genome Res. 33, 557\u2013571 (2023).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1101\/gr.277434.122\" data-track-item_id=\"10.1101\/gr.277434.122\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1101%2Fgr.277434.122\" aria-label=\"Article reference 60\" data-doi=\"10.1101\/gr.277434.122\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB2cXitFyqu7nF\" aria-label=\"CAS reference 60\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10234306\" aria-label=\"PubMed Central reference 60\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 60\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=High%20resolution%20genomes%20of%20multiple%20Xiphophorus%20species%20provide%20new%20insights%20into%20microevolution%2C%20hybrid%20incompatibility%2C%20and%20epistasis&amp;journal=Genome%20Res.&amp;doi=10.1101%2Fgr.277434.122&amp;volume=33&amp;pages=557-571&amp;publication_year=2023&amp;author=Lu%2CY\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR61\">Dfam Consortium. TETools: Dfam transposable element tools docker container. Github <a href=\"https:\/\/github.com\/Dfam-consortium\/TETools\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"https:\/\/github.com\/Dfam-consortium\/TETools\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/github.com\/Dfam-consortium\/TETools<\/a> (2022).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR62\">Du, K. et al. Phylogenomic analyses of all species of swordtail fishes (genus Xiphophorus) show that hybridization preceded speciation. Nat. Commun. 15, 6609 (2024).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/s41467-024-50852-6\" data-track-item_id=\"10.1038\/s41467-024-50852-6\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fs41467-024-50852-6\" aria-label=\"Article reference 62\" data-doi=\"10.1038\/s41467-024-50852-6\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"ads reference\" data-track-action=\"ads reference\" href=\"http:\/\/adsabs.harvard.edu\/cgi-bin\/nph-data_query?link_type=ABSTRACT&amp;bibcode=2024NatCo..15.6614D\" aria-label=\"ADS reference 62\" target=\"_blank\">ADS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB2cXhslKgtb7O\" aria-label=\"CAS reference 62\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC11298535\" aria-label=\"PubMed Central reference 62\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 62\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Phylogenomic%20analyses%20of%20all%20species%20of%20swordtail%20fishes%20%28genus%20Xiphophorus%29%20show%20that%20hybridization%20preceded%20speciation&amp;journal=Nat.%20Commun.&amp;doi=10.1038%2Fs41467-024-50852-6&amp;volume=15&amp;publication_year=2024&amp;author=Du%2CK\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR63\">Stanke, M. et al. AUGUSTUS: ab initio prediction of alternative transcripts. Nucleic Acids Res. 34, W435\u20139 (2006).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/nar\/gkl200\" data-track-item_id=\"10.1093\/nar\/gkl200\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fnar%2Fgkl200\" aria-label=\"Article reference 63\" data-doi=\"10.1093\/nar\/gkl200\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BD28Xps1yiu78%3D\" aria-label=\"CAS reference 63\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1538822\" aria-label=\"PubMed Central reference 63\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 63\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=AUGUSTUS%3A%20ab%20initio%20prediction%20of%20alternative%20transcripts&amp;journal=Nucleic%20Acids%20Res.&amp;doi=10.1093%2Fnar%2Fgkl200&amp;volume=34&amp;pages=W435-9&amp;publication_year=2006&amp;author=Stanke%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR64\">Boutet, E., Lieberherr, D., Tognolli, M., Schneider, M. &amp; Bairoch, A. UniProtKB\/Swiss-Prot. Methods Mol. Biol. 406, 89\u2013112 (2007).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BD1cXhvVCnur0%3D\" aria-label=\"CAS reference 64\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 64\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=UniProtKB%2FSwiss-Prot&amp;journal=Methods%20Mol.%20Biol.&amp;volume=406&amp;pages=89-112&amp;publication_year=2007&amp;author=Boutet%2CE&amp;author=Lieberherr%2CD&amp;author=Tognolli%2CM&amp;author=Schneider%2CM&amp;author=Bairoch%2CA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR65\">Birney, E., Clamp, M. &amp; Durbin, R. GeneWise and Genomewise. Genome Res. 14, 988\u2013995 (2004).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1101\/gr.1865504\" data-track-item_id=\"10.1101\/gr.1865504\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1101%2Fgr.1865504\" aria-label=\"Article reference 65\" data-doi=\"10.1101\/gr.1865504\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BD2cXjvFyku7c%3D\" aria-label=\"CAS reference 65\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC479130\" aria-label=\"PubMed Central reference 65\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 65\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=GeneWise%20and%20Genomewise&amp;journal=Genome%20Res.&amp;doi=10.1101%2Fgr.1865504&amp;volume=14&amp;pages=988-995&amp;publication_year=2004&amp;author=Birney%2CE&amp;author=Clamp%2CM&amp;author=Durbin%2CR\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR66\">Slater, G. S. C. &amp; Birney, E. Automated generation of heuristics for biological sequence comparison. BMC Bioinformatics 6, 31 (2005).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1186\/1471-2105-6-31\" data-track-item_id=\"10.1186\/1471-2105-6-31\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1186\/1471-2105-6-31\" aria-label=\"Article reference 66\" data-doi=\"10.1186\/1471-2105-6-31\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC553969\" aria-label=\"PubMed Central reference 66\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 66\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Automated%20generation%20of%20heuristics%20for%20biological%20sequence%20comparison&amp;journal=BMC%20Bioinformatics&amp;doi=10.1186%2F1471-2105-6-31&amp;volume=6&amp;publication_year=2005&amp;author=Slater%2CGSC&amp;author=Birney%2CE\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR67\">She, R., Chu, J. S.-C., Wang, K., Pei, J. &amp; Chen, N. GenBlastA: enabling BLAST to identify homologous gene sequences. Genome Res. 19, 143\u2013149 (2009).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1101\/gr.082081.108\" data-track-item_id=\"10.1101\/gr.082081.108\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1101%2Fgr.082081.108\" aria-label=\"Article reference 67\" data-doi=\"10.1101\/gr.082081.108\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BD1MXptFWitg%3D%3D\" aria-label=\"CAS reference 67\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 67\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=GenBlastA%3A%20enabling%20BLAST%20to%20identify%20homologous%20gene%20sequences&amp;journal=Genome%20Res.&amp;doi=10.1101%2Fgr.082081.108&amp;volume=19&amp;pages=143-149&amp;publication_year=2009&amp;author=She%2CR&amp;author=Chu%2CJS-C&amp;author=Wang%2CK&amp;author=Pei%2CJ&amp;author=Chen%2CN\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR68\">Kim, D., Langmead, B. &amp; Salzberg, S. L. HISAT: a fast spliced aligner with low memory requirements. Nat. Methods 12, 357\u2013360 (2015).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/nmeth.3317\" data-track-item_id=\"10.1038\/nmeth.3317\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fnmeth.3317\" aria-label=\"Article reference 68\" data-doi=\"10.1038\/nmeth.3317\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC2MXjvFOnsL0%3D\" aria-label=\"CAS reference 68\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4655817\" aria-label=\"PubMed Central reference 68\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 68\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=HISAT%3A%20a%20fast%20spliced%20aligner%20with%20low%20memory%20requirements&amp;journal=Nat.%20Methods&amp;doi=10.1038%2Fnmeth.3317&amp;volume=12&amp;pages=357-360&amp;publication_year=2015&amp;author=Kim%2CD&amp;author=Langmead%2CB&amp;author=Salzberg%2CSL\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR69\">Pertea, M. et al. StringTie enables improved reconstruction of a transcriptome from RNA-seq reads. Nat. Biotechnol. 33, 290\u2013295 (2015).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/nbt.3122\" data-track-item_id=\"10.1038\/nbt.3122\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fnbt.3122\" aria-label=\"Article reference 69\" data-doi=\"10.1038\/nbt.3122\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC2MXivFais70%3D\" aria-label=\"CAS reference 69\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4643835\" aria-label=\"PubMed Central reference 69\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 69\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=StringTie%20enables%20improved%20reconstruction%20of%20a%20transcriptome%20from%20RNA-seq%20reads&amp;journal=Nat.%20Biotechnol.&amp;doi=10.1038%2Fnbt.3122&amp;volume=33&amp;pages=290-295&amp;publication_year=2015&amp;author=Pertea%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR70\">Grabherr, M. G. et al. Full-length transcriptome assembly from RNA-seq data without a reference genome. Nat. Biotechnol. 29, 644\u2013652 (2011).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/nbt.1883\" data-track-item_id=\"10.1038\/nbt.1883\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fnbt.1883\" aria-label=\"Article reference 70\" data-doi=\"10.1038\/nbt.1883\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC3MXmtV2hsbc%3D\" aria-label=\"CAS reference 70\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3571712\" aria-label=\"PubMed Central reference 70\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 70\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Full-length%20transcriptome%20assembly%20from%20RNA-seq%20data%20without%20a%20reference%20genome&amp;journal=Nat.%20Biotechnol.&amp;doi=10.1038%2Fnbt.1883&amp;volume=29&amp;pages=644-652&amp;publication_year=2011&amp;author=Grabherr%2CMG\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR71\">Kapustin, Y., Souvorov, A., Tatusova, T. &amp; Lipman, D. Splign: algorithms for computing spliced alignments with identification of paralogs. Biol. Direct 3, 20 (2008).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1186\/1745-6150-3-20\" data-track-item_id=\"10.1186\/1745-6150-3-20\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1186\/1745-6150-3-20\" aria-label=\"Article reference 71\" data-doi=\"10.1186\/1745-6150-3-20\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2440734\" aria-label=\"PubMed Central reference 71\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 71\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Splign%3A%20algorithms%20for%20computing%20spliced%20alignments%20with%20identification%20of%20paralogs&amp;journal=Biol.%20Direct&amp;doi=10.1186%2F1745-6150-3-20&amp;volume=3&amp;publication_year=2008&amp;author=Kapustin%2CY&amp;author=Souvorov%2CA&amp;author=Tatusova%2CT&amp;author=Lipman%2CD\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR72\">Sim\u00e3o, F. A., Waterhouse, R. M., Ioannidis, P., Kriventseva, E. V. &amp; Zdobnov, E. M. BUSCO: assessing genome assembly and annotation completeness with single-copy orthologs. Bioinformatics 31, 3210\u20133212 (2015).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/bioinformatics\/btv351\" data-track-item_id=\"10.1093\/bioinformatics\/btv351\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fbioinformatics%2Fbtv351\" aria-label=\"Article reference 72\" data-doi=\"10.1093\/bioinformatics\/btv351\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 72\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=BUSCO%3A%20assessing%20genome%20assembly%20and%20annotation%20completeness%20with%20single-copy%20orthologs&amp;journal=Bioinformatics&amp;doi=10.1093%2Fbioinformatics%2Fbtv351&amp;volume=31&amp;pages=3210-3212&amp;publication_year=2015&amp;author=Sim%C3%A3o%2CFA&amp;author=Waterhouse%2CRM&amp;author=Ioannidis%2CP&amp;author=Kriventseva%2CEV&amp;author=Zdobnov%2CEM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR73\">Darolti, I. et al. Extreme heterogeneity in sex chromosome differentiation and dosage compensation in livebearers. Proc. Natl Acad. Sci. USA 116, 19031\u201319036 (2019).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1073\/pnas.1905298116\" data-track-item_id=\"10.1073\/pnas.1905298116\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1073%2Fpnas.1905298116\" aria-label=\"Article reference 73\" data-doi=\"10.1073\/pnas.1905298116\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"ads reference\" data-track-action=\"ads reference\" href=\"http:\/\/adsabs.harvard.edu\/cgi-bin\/nph-data_query?link_type=ABSTRACT&amp;bibcode=2019PNAS..11619031D\" aria-label=\"ADS reference 73\" target=\"_blank\">ADS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC1MXhvVSku7zJ\" aria-label=\"CAS reference 73\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6754558\" aria-label=\"PubMed Central reference 73\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 73\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Extreme%20heterogeneity%20in%20sex%20chromosome%20differentiation%20and%20dosage%20compensation%20in%20livebearers&amp;journal=Proc.%20Natl%20Acad.%20Sci.%20USA&amp;doi=10.1073%2Fpnas.1905298116&amp;volume=116&amp;pages=19031-19036&amp;publication_year=2019&amp;author=Darolti%2CI\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR74\">Greenway, R. et al. Convergent evolution of conserved mitochondrial pathways underlies repeated adaptation to extreme environments. Proc. Natl Acad. Sci. USA 117, 16424\u201316430 (2020).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1073\/pnas.2004223117\" data-track-item_id=\"10.1073\/pnas.2004223117\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1073%2Fpnas.2004223117\" aria-label=\"Article reference 74\" data-doi=\"10.1073\/pnas.2004223117\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"ads reference\" data-track-action=\"ads reference\" href=\"http:\/\/adsabs.harvard.edu\/cgi-bin\/nph-data_query?link_type=ABSTRACT&amp;bibcode=2020PNAS..11716424G\" aria-label=\"ADS reference 74\" target=\"_blank\">ADS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3cXhsFahsbnL\" aria-label=\"CAS reference 74\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7368198\" aria-label=\"PubMed Central reference 74\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 74\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Convergent%20evolution%20of%20conserved%20mitochondrial%20pathways%20underlies%20repeated%20adaptation%20to%20extreme%20environments&amp;journal=Proc.%20Natl%20Acad.%20Sci.%20USA&amp;doi=10.1073%2Fpnas.2004223117&amp;volume=117&amp;pages=16424-16430&amp;publication_year=2020&amp;author=Greenway%2CR\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR75\">De-Kayne, R. et al. Evolutionary rate shifts in coding and regulatory regions underpin repeated adaptation to sulfidic streams in poeciliid fishes. Genome Biol. Evol. 16, evae087 (2024).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/gbe\/evae087\" data-track-item_id=\"10.1093\/gbe\/evae087\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fgbe%2Fevae087\" aria-label=\"Article reference 75\" data-doi=\"10.1093\/gbe\/evae087\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC11126329\" aria-label=\"PubMed Central reference 75\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 75\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Evolutionary%20rate%20shifts%20in%20coding%20and%20regulatory%20regions%20underpin%20repeated%20adaptation%20to%20sulfidic%20streams%20in%20poeciliid%20fishes&amp;journal=Genome%20Biol.%20Evol.&amp;doi=10.1093%2Fgbe%2Fevae087&amp;volume=16&amp;publication_year=2024&amp;author=De-Kayne%2CR\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR76\">Herzeel, C. et al. Multithreaded variant calling in elPrep 5. PLoS ONE 16, e0244471 (2021).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1371\/journal.pone.0244471\" data-track-item_id=\"10.1371\/journal.pone.0244471\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1371%2Fjournal.pone.0244471\" aria-label=\"Article reference 76\" data-doi=\"10.1371\/journal.pone.0244471\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3MXjslChs7k%3D\" aria-label=\"CAS reference 76\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7861424\" aria-label=\"PubMed Central reference 76\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 76\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Multithreaded%20variant%20calling%20in%20elPrep%205&amp;journal=PLoS%20ONE&amp;doi=10.1371%2Fjournal.pone.0244471&amp;volume=16&amp;publication_year=2021&amp;author=Herzeel%2CC\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR77\">Van der Auwera, G. A. &amp; O\u2019Connor, B. D. Genomics in the Cloud: Using Docker, GATK, and WDL in Terra (O\u2019Reilly Media, 2020).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR78\">Martin, M., Ebert, P. &amp; Marschall, T. Read-based phasing and analysis of phased variants with WhatsHap. Methods Mol. Biol. 2590, 127\u2013138 (2023).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1007\/978-1-0716-2819-5_8\" data-track-item_id=\"10.1007\/978-1-0716-2819-5_8\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1007\/978-1-0716-2819-5_8\" aria-label=\"Article reference 78\" data-doi=\"10.1007\/978-1-0716-2819-5_8\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3sXit1SrsL7N\" aria-label=\"CAS reference 78\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 78\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Read-based%20phasing%20and%20analysis%20of%20phased%20variants%20with%20WhatsHap&amp;journal=Methods%20Mol.%20Biol.&amp;doi=10.1007%2F978-1-0716-2819-5_8&amp;volume=2590&amp;pages=127-138&amp;publication_year=2023&amp;author=Martin%2CM&amp;author=Ebert%2CP&amp;author=Marschall%2CT\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR79\">Armstrong, J. et al. Progressive Cactus is a multiple-genome aligner for the thousand-genome era. Nature 587, 246\u2013251 (2020).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/s41586-020-2871-y\" data-track-item_id=\"10.1038\/s41586-020-2871-y\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fs41586-020-2871-y\" aria-label=\"Article reference 79\" data-doi=\"10.1038\/s41586-020-2871-y\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"ads reference\" data-track-action=\"ads reference\" href=\"http:\/\/adsabs.harvard.edu\/cgi-bin\/nph-data_query?link_type=ABSTRACT&amp;bibcode=2020Natur.587..246A\" aria-label=\"ADS reference 79\" target=\"_blank\">ADS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3cXitlWktLnF\" aria-label=\"CAS reference 79\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7673649\" aria-label=\"PubMed Central reference 79\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 79\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Progressive%20Cactus%20is%20a%20multiple-genome%20aligner%20for%20the%20thousand-genome%20era&amp;journal=Nature&amp;doi=10.1038%2Fs41586-020-2871-y&amp;volume=587&amp;pages=246-251&amp;publication_year=2020&amp;author=Armstrong%2CJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR80\">Fraser, B. A. et al. Improved reference genome uncovers novel sex-linked regions in the guppy (Poecilia reticulata). Genome Biol. Evol. 12, 1789\u20131805 (2020).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/gbe\/evaa187\" data-track-item_id=\"10.1093\/gbe\/evaa187\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fgbe%2Fevaa187\" aria-label=\"Article reference 80\" data-doi=\"10.1093\/gbe\/evaa187\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3MXnvVKhs7g%3D\" aria-label=\"CAS reference 80\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7643365\" aria-label=\"PubMed Central reference 80\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 80\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Improved%20reference%20genome%20uncovers%20novel%20sex-linked%20regions%20in%20the%20guppy%20%28Poecilia%20reticulata%29&amp;journal=Genome%20Biol.%20Evol.&amp;doi=10.1093%2Fgbe%2Fevaa187&amp;volume=12&amp;pages=1789-1805&amp;publication_year=2020&amp;author=Fraser%2CBA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR81\">Fraser, B. A., K\u00fcnstner, A., Reznick, D. N., Dreyer, C. &amp; Weigel, D. Population genomics of natural and experimental populations of guppies (Poecilia reticulata). Mol. Ecol. 24, 389\u2013408 (2015).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1111\/mec.13022\" data-track-item_id=\"10.1111\/mec.13022\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1111%2Fmec.13022\" aria-label=\"Article reference 81\" data-doi=\"10.1111\/mec.13022\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 81\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Population%20genomics%20of%20natural%20and%20experimental%20populations%20of%20guppies%20%28Poecilia%20reticulata%29&amp;journal=Mol.%20Ecol.&amp;doi=10.1111%2Fmec.13022&amp;volume=24&amp;pages=389-408&amp;publication_year=2015&amp;author=Fraser%2CBA&amp;author=K%C3%BCnstner%2CA&amp;author=Reznick%2CDN&amp;author=Dreyer%2CC&amp;author=Weigel%2CD\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR82\">Altschul, S. F., Gish, W., Miller, W., Myers, E. W. &amp; Lipman, D. J. Basic local alignment search tool. J. Mol. Biol. 215, 403\u2013410 (1990).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1016\/S0022-2836(05)80360-2\" data-track-item_id=\"10.1016\/S0022-2836(05)80360-2\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1016%2FS0022-2836%2805%2980360-2\" aria-label=\"Article reference 82\" data-doi=\"10.1016\/S0022-2836(05)80360-2\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DyaK3MXitVGmsA%3D%3D\" aria-label=\"CAS reference 82\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 82\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Basic%20local%20alignment%20search%20tool&amp;journal=J.%20Mol.%20Biol.&amp;doi=10.1016%2FS0022-2836%2805%2980360-2&amp;volume=215&amp;pages=403-410&amp;publication_year=1990&amp;author=Altschul%2CSF&amp;author=Gish%2CW&amp;author=Miller%2CW&amp;author=Myers%2CEW&amp;author=Lipman%2CDJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR83\">The Gene Ontology Consortium The Gene Ontology knowledgebase in 2023. Genetics 224, iyad031 (2023).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/genetics\/iyad031\" data-track-item_id=\"10.1093\/genetics\/iyad031\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fgenetics%2Fiyad031\" aria-label=\"Article reference 83\" data-doi=\"10.1093\/genetics\/iyad031\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 83\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20Gene%20Ontology%20knowledgebase%20in%202023&amp;journal=Genetics&amp;doi=10.1093%2Fgenetics%2Fiyad031&amp;volume=224&amp;publication_year=2023\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR84\">Smedley, D. et al. BioMart-biological queries made easy. BMC Genomics 10, 22 (2009).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1186\/1471-2164-10-22\" data-track-item_id=\"10.1186\/1471-2164-10-22\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1186\/1471-2164-10-22\" aria-label=\"Article reference 84\" data-doi=\"10.1186\/1471-2164-10-22\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2649164\" aria-label=\"PubMed Central reference 84\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 84\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=BioMart-biological%20queries%20made%20easy&amp;journal=BMC%20Genomics&amp;doi=10.1186%2F1471-2164-10-22&amp;volume=10&amp;publication_year=2009&amp;author=Smedley%2CD\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR85\">Yang, Z. PAML: a program package for phylogenetic analysis by maximum likelihood. Comput. Appl. Biosci. 13, 555\u2013556 (1997).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DyaK2sXntlGnu7s%3D\" aria-label=\"CAS reference 85\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 85\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=PAML%3A%20a%20program%20package%20for%20phylogenetic%20analysis%20by%20maximum%20likelihood&amp;journal=Comput.%20Appl.%20Biosci.&amp;volume=13&amp;pages=555-556&amp;publication_year=1997&amp;author=Yang%2CZ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR86\">Yang, Z. &amp; Nielsen, R. Estimating synonymous and nonsynonymous substitution rates under realistic evolutionary models. Mol. Biol. Evol. 17, 32\u201343 (2000).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/oxfordjournals.molbev.a026236\" data-track-item_id=\"10.1093\/oxfordjournals.molbev.a026236\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Foxfordjournals.molbev.a026236\" aria-label=\"Article reference 86\" data-doi=\"10.1093\/oxfordjournals.molbev.a026236\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BD3cXotF2qtA%3D%3D\" aria-label=\"CAS reference 86\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 86\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Estimating%20synonymous%20and%20nonsynonymous%20substitution%20rates%20under%20realistic%20evolutionary%20models&amp;journal=Mol.%20Biol.%20Evol.&amp;doi=10.1093%2Foxfordjournals.molbev.a026236&amp;volume=17&amp;pages=32-43&amp;publication_year=2000&amp;author=Yang%2CZ&amp;author=Nielsen%2CR\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR87\">McDonald, J. H. &amp; Kreitman, M. Adaptive protein evolution at the Adh locus in Drosophila. Nature 351, 652\u2013654 (1991).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/351652a0\" data-track-item_id=\"10.1038\/351652a0\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2F351652a0\" aria-label=\"Article reference 87\" data-doi=\"10.1038\/351652a0\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"ads reference\" data-track-action=\"ads reference\" href=\"http:\/\/adsabs.harvard.edu\/cgi-bin\/nph-data_query?link_type=ABSTRACT&amp;bibcode=1991Natur.351..652M\" aria-label=\"ADS reference 87\" target=\"_blank\">ADS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DyaK3MXks1yrtLs%3D\" aria-label=\"CAS reference 87\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 87\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Adaptive%20protein%20evolution%20at%20the%20Adh%20locus%20in%20Drosophila&amp;journal=Nature&amp;doi=10.1038%2F351652a0&amp;volume=351&amp;pages=652-654&amp;publication_year=1991&amp;author=McDonald%2CJH&amp;author=Kreitman%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR88\">Cingolani, P. et al. A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff. Fly 6, 80\u201392 (2012).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.4161\/fly.19695\" data-track-item_id=\"10.4161\/fly.19695\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.4161%2Ffly.19695\" aria-label=\"Article reference 88\" data-doi=\"10.4161\/fly.19695\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC38Xht1GmtL3E\" aria-label=\"CAS reference 88\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3679285\" aria-label=\"PubMed Central reference 88\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 88\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=A%20program%20for%20annotating%20and%20predicting%20the%20effects%20of%20single%20nucleotide%20polymorphisms%2C%20SnpEff&amp;journal=Fly&amp;doi=10.4161%2Ffly.19695&amp;volume=6&amp;pages=80-92&amp;publication_year=2012&amp;author=Cingolani%2CP\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR89\">Hickey, G., Paten, B., Earl, D., Zerbino, D. &amp; Haussler, D. HAL: a hierarchical format for storing and analyzing multiple genome alignments. Bioinformatics 29, 1341\u20131342 (2013).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/bioinformatics\/btt128\" data-track-item_id=\"10.1093\/bioinformatics\/btt128\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fbioinformatics%2Fbtt128\" aria-label=\"Article reference 89\" data-doi=\"10.1093\/bioinformatics\/btt128\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC3sXnvV2mtr8%3D\" aria-label=\"CAS reference 89\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3654707\" aria-label=\"PubMed Central reference 89\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 89\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=HAL%3A%20a%20hierarchical%20format%20for%20storing%20and%20analyzing%20multiple%20genome%20alignments&amp;journal=Bioinformatics&amp;doi=10.1093%2Fbioinformatics%2Fbtt128&amp;volume=29&amp;pages=1341-1342&amp;publication_year=2013&amp;author=Hickey%2CG&amp;author=Paten%2CB&amp;author=Earl%2CD&amp;author=Zerbino%2CD&amp;author=Haussler%2CD\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR90\">Ondov, B. D. et al. Mash: fast genome and metagenome distance estimation using MinHash. Genome Biol. 17, 132 (2016).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1186\/s13059-016-0997-x\" data-track-item_id=\"10.1186\/s13059-016-0997-x\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1186\/s13059-016-0997-x\" aria-label=\"Article reference 90\" data-doi=\"10.1186\/s13059-016-0997-x\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4915045\" aria-label=\"PubMed Central reference 90\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 90\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Mash%3A%20fast%20genome%20and%20metagenome%20distance%20estimation%20using%20MinHash&amp;journal=Genome%20Biol.&amp;doi=10.1186%2Fs13059-016-0997-x&amp;volume=17&amp;publication_year=2016&amp;author=Ondov%2CBD\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR91\">Cock, P. J. A. et al. Biopython: freely available Python tools for computational molecular biology and bioinformatics. Bioinformatics 25, 1422\u20131423 (2009).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/bioinformatics\/btp163\" data-track-item_id=\"10.1093\/bioinformatics\/btp163\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fbioinformatics%2Fbtp163\" aria-label=\"Article reference 91\" data-doi=\"10.1093\/bioinformatics\/btp163\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BD1MXmtFeqt74%3D\" aria-label=\"CAS reference 91\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2682512\" aria-label=\"PubMed Central reference 91\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 91\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Biopython%3A%20freely%20available%20Python%20tools%20for%20computational%20molecular%20biology%20and%20bioinformatics&amp;journal=Bioinformatics&amp;doi=10.1093%2Fbioinformatics%2Fbtp163&amp;volume=25&amp;pages=1422-1423&amp;publication_year=2009&amp;author=Cock%2CPJA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR92\">Durand, N. C. et al. Juicer provides a one-click system for analyzing loop-resolution Hi-C experiments. Cell Syst. 3, 95\u201398 (2016).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1016\/j.cels.2016.07.002\" data-track-item_id=\"10.1016\/j.cels.2016.07.002\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1016%2Fj.cels.2016.07.002\" aria-label=\"Article reference 92\" data-doi=\"10.1016\/j.cels.2016.07.002\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC2sXhtFKksbk%3D\" aria-label=\"CAS reference 92\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5846465\" aria-label=\"PubMed Central reference 92\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 92\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Juicer%20provides%20a%20one-click%20system%20for%20analyzing%20loop-resolution%20Hi-C%20experiments&amp;journal=Cell%20Syst.&amp;doi=10.1016%2Fj.cels.2016.07.002&amp;volume=3&amp;pages=95-98&amp;publication_year=2016&amp;author=Durand%2CNC\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR93\">Li, A., Zeng, G., Wang, H., Li, X. &amp; Zhang, Z. DeDoc2 identifies and characterizes the hierarchy and dynamics of chromatin TAD-like domains in the single cells. Adv. Sci. 10, e2300366 (2023).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1002\/advs.202300366\" data-track-item_id=\"10.1002\/advs.202300366\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1002%2Fadvs.202300366\" aria-label=\"Article reference 93\" data-doi=\"10.1002\/advs.202300366\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 93\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=DeDoc2%20identifies%20and%20characterizes%20the%20hierarchy%20and%20dynamics%20of%20chromatin%20TAD-like%20domains%20in%20the%20single%20cells&amp;journal=Adv.%20Sci.&amp;doi=10.1002%2Fadvs.202300366&amp;volume=10&amp;publication_year=2023&amp;author=Li%2CA&amp;author=Zeng%2CG&amp;author=Wang%2CH&amp;author=Li%2CX&amp;author=Zhang%2CZ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR94\">Kruse, K., Hug, C. B. &amp; Vaquerizas, J. M. FAN-C: a feature-rich framework for the analysis and visualisation of chromosome conformation capture data. Genome Biol. 21, 303 (2020).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1186\/s13059-020-02215-9\" data-track-item_id=\"10.1186\/s13059-020-02215-9\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1186\/s13059-020-02215-9\" aria-label=\"Article reference 94\" data-doi=\"10.1186\/s13059-020-02215-9\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7745377\" aria-label=\"PubMed Central reference 94\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 94\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=FAN-C%3A%20a%20feature-rich%20framework%20for%20the%20analysis%20and%20visualisation%20of%20chromosome%20conformation%20capture%20data&amp;journal=Genome%20Biol.&amp;doi=10.1186%2Fs13059-020-02215-9&amp;volume=21&amp;publication_year=2020&amp;author=Kruse%2CK&amp;author=Hug%2CCB&amp;author=Vaquerizas%2CJM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR95\">Gu, Z., Eils, R., Schlesner, M. &amp; Ishaque, N. EnrichedHeatmap: an R\/Bioconductor package for comprehensive visualization of genomic signal associations. BMC Genomics 19, 234 (2018).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1186\/s12864-018-4625-x\" data-track-item_id=\"10.1186\/s12864-018-4625-x\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1186\/s12864-018-4625-x\" aria-label=\"Article reference 95\" data-doi=\"10.1186\/s12864-018-4625-x\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5885322\" aria-label=\"PubMed Central reference 95\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 95\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=EnrichedHeatmap%3A%20an%20R%2FBioconductor%20package%20for%20comprehensive%20visualization%20of%20genomic%20signal%20associations&amp;journal=BMC%20Genomics&amp;doi=10.1186%2Fs12864-018-4625-x&amp;volume=19&amp;publication_year=2018&amp;author=Gu%2CZ&amp;author=Eils%2CR&amp;author=Schlesner%2CM&amp;author=Ishaque%2CN\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR96\">Danecek, P. et al. Twelve years of SAMtools and BCFtools. GigaScience 10, giab008 (2021).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/gigascience\/giab008\" data-track-item_id=\"10.1093\/gigascience\/giab008\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fgigascience%2Fgiab008\" aria-label=\"Article reference 96\" data-doi=\"10.1093\/gigascience\/giab008\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7931819\" aria-label=\"PubMed Central reference 96\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 96\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Twelve%20years%20of%20SAMtools%20and%20BCFtools&amp;journal=GigaScience&amp;doi=10.1093%2Fgigascience%2Fgiab008&amp;volume=10&amp;publication_year=2021&amp;author=Danecek%2CP\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR97\">Robinson, J. T. et al. Integrative genomics viewer. Nat. Biotechnol. 29, 24\u201326 (2011).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/nbt.1754\" data-track-item_id=\"10.1038\/nbt.1754\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fnbt.1754\" aria-label=\"Article reference 97\" data-doi=\"10.1038\/nbt.1754\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC3MXjsFWrtg%3D%3D\" aria-label=\"CAS reference 97\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3346182\" aria-label=\"PubMed Central reference 97\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 97\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Integrative%20genomics%20viewer&amp;journal=Nat.%20Biotechnol.&amp;doi=10.1038%2Fnbt.1754&amp;volume=29&amp;pages=24-26&amp;publication_year=2011&amp;author=Robinson%2CJT\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR98\">Rogers, A. R. &amp; Huff, C. Linkage disequilibrium between loci with unknown phase. Genetics 182, 839\u2013844 (2009).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1534\/genetics.108.093153\" data-track-item_id=\"10.1534\/genetics.108.093153\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1534%2Fgenetics.108.093153\" aria-label=\"Article reference 98\" data-doi=\"10.1534\/genetics.108.093153\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2710162\" aria-label=\"PubMed Central reference 98\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 98\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Linkage%20disequilibrium%20between%20loci%20with%20unknown%20phase&amp;journal=Genetics&amp;doi=10.1534%2Fgenetics.108.093153&amp;volume=182&amp;pages=839-844&amp;publication_year=2009&amp;author=Rogers%2CAR&amp;author=Huff%2CC\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR99\">Quinlan, A. R. &amp; Hall, I. M. BEDTools: a flexible suite of utilities for comparing genomic features. Bioinformatics 26, 841\u2013842 (2010).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/bioinformatics\/btq033\" data-track-item_id=\"10.1093\/bioinformatics\/btq033\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fbioinformatics%2Fbtq033\" aria-label=\"Article reference 99\" data-doi=\"10.1093\/bioinformatics\/btq033\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC3cXivFGkurc%3D\" aria-label=\"CAS reference 99\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2832824\" aria-label=\"PubMed Central reference 99\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 99\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=BEDTools%3A%20a%20flexible%20suite%20of%20utilities%20for%20comparing%20genomic%20features&amp;journal=Bioinformatics&amp;doi=10.1093%2Fbioinformatics%2Fbtq033&amp;volume=26&amp;pages=841-842&amp;publication_year=2010&amp;author=Quinlan%2CAR&amp;author=Hall%2CIM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR100\">Purcell, S. et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am. J. Hum. Genet. 81, 559\u2013575 (2007).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1086\/519795\" data-track-item_id=\"10.1086\/519795\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1086%2F519795\" aria-label=\"Article reference 100\" data-doi=\"10.1086\/519795\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BD2sXhtVSqurrL\" aria-label=\"CAS reference 100\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1950838\" aria-label=\"PubMed Central reference 100\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 100\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=PLINK%3A%20a%20tool%20set%20for%20whole-genome%20association%20and%20population-based%20linkage%20analyses&amp;journal=Am.%20J.%20Hum.%20Genet.&amp;doi=10.1086%2F519795&amp;volume=81&amp;pages=559-575&amp;publication_year=2007&amp;author=Purcell%2CS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR101\">Fitch, W. M. Toward defining the course of evolution: minimum change for a specific tree topology. Syst. Zool. 20, 406 (1971).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.2307\/2412116\" data-track-item_id=\"10.2307\/2412116\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.2307%2F2412116\" aria-label=\"Article reference 101\" data-doi=\"10.2307\/2412116\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 101\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Toward%20defining%20the%20course%20of%20evolution%3A%20minimum%20change%20for%20a%20specific%20tree%20topology&amp;journal=Syst.%20Zool.&amp;doi=10.2307%2F2412116&amp;volume=20&amp;publication_year=1971&amp;author=Fitch%2CWM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR102\">Pr\u00fcfer, K. et al. FUNC: a package for detecting significant associations between gene sets and ontological annotations. BMC Bioinformatics 8, 41 (2007).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1186\/1471-2105-8-41\" data-track-item_id=\"10.1186\/1471-2105-8-41\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1186\/1471-2105-8-41\" aria-label=\"Article reference 102\" data-doi=\"10.1186\/1471-2105-8-41\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1800870\" aria-label=\"PubMed Central reference 102\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 102\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=FUNC%3A%20a%20package%20for%20detecting%20significant%20associations%20between%20gene%20sets%20and%20ontological%20annotations&amp;journal=BMC%20Bioinformatics&amp;doi=10.1186%2F1471-2105-8-41&amp;volume=8&amp;publication_year=2007&amp;author=Pr%C3%BCfer%2CK\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR103\">Szklarczyk, D. et al. The STRING database in 2023: protein\u2013protein association networks and functional enrichment analyses for any sequenced genome of interest. Nucleic Acids Res. 51, D638\u2013D646 (2023).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/nar\/gkac1000\" data-track-item_id=\"10.1093\/nar\/gkac1000\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fnar%2Fgkac1000\" aria-label=\"Article reference 103\" data-doi=\"10.1093\/nar\/gkac1000\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3sXht1entL3K\" aria-label=\"CAS reference 103\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9825434\" aria-label=\"PubMed Central reference 103\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 103\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20STRING%20database%20in%202023%3A%20protein%E2%80%93protein%20association%20networks%20and%20functional%20enrichment%20analyses%20for%20any%20sequenced%20genome%20of%20interest&amp;journal=Nucleic%20Acids%20Res.&amp;doi=10.1093%2Fnar%2Fgkac1000&amp;volume=51&amp;pages=D638-D646&amp;publication_year=2023&amp;author=Szklarczyk%2CD\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR104\">Ricemeyer, E. S., Schaefer, N. &amp; Acemel, R. D. esrice\/amazon-molly-paper: Zenodo DOI release (v0.0.3). Zenodo <a href=\"https:\/\/doi.org\/10.5281\/zenodo.17976428\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.5281\/zenodo.17976428\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.5281\/zenodo.17976428<\/a> (2025).<\/p>\n","protected":false},"excerpt":{"rendered":"Speijer, D., Luke\u0161, J. &amp; Eli\u00e1\u0161, M. Sex is a ubiquitous, ancient, and inherent attribute of eukaryotic life.&hellip;\n","protected":false},"author":2,"featured_media":519403,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[32],"tags":[201442,70007,1159,70008,1160,21875,43699,79],"class_list":["post-519402","post","type-post","status-publish","format-standard","has-post-thumbnail","category-science","tag-dna-recombination","tag-evolutionary-genetics","tag-humanities-and-social-sciences","tag-molecular-evolution","tag-multidisciplinary","tag-mutation","tag-population-genetics","tag-science"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/519402","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/comments?post=519402"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/519402\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media\/519403"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media?parent=519402"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/categories?post=519402"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/tags?post=519402"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}