{"id":582852,"date":"2026-04-14T03:16:12","date_gmt":"2026-04-14T03:16:12","guid":{"rendered":"https:\/\/www.newsbeep.com\/us\/582852\/"},"modified":"2026-04-14T03:16:12","modified_gmt":"2026-04-14T03:16:12","slug":"de-novo-formation-of-cis-regulatory-contacts-in-the-absence-of-nipbl-driven-chromatin-loop-extrusion","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us\/582852\/","title":{"rendered":"De novo formation of cis-regulatory contacts in the absence of NIPBL-driven chromatin loop extrusion"},"content":{"rendered":"<p class=\"c-article-references__text\" id=\"ref-CR1\">Vermunt, M. W., Zhang, D. &amp; Blobel, G. A. The interdependence of gene-regulatory elements and the 3D genome. J. 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