{"id":583685,"date":"2026-04-14T13:29:09","date_gmt":"2026-04-14T13:29:09","guid":{"rendered":"https:\/\/www.newsbeep.com\/us\/583685\/"},"modified":"2026-04-14T13:29:09","modified_gmt":"2026-04-14T13:29:09","slug":"study-links-eating-more-meat-to-lower-dementia-risk-but-only-in-one-group-sciencealert","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us\/583685\/","title":{"rendered":"Study Links Eating More Meat to Lower Dementia Risk, But Only in One Group : ScienceAlert"},"content":{"rendered":"<p>A surprising new observational study has found a tentative connection between eating more meat of any kind and a lower risk of <a href=\"https:\/\/www.sciencealert.com\/how-rare-you-like-your-steak-could-be-linked-to-your-dementia-risk\" rel=\"nofollow noopener\" target=\"_blank\">developing dementia<\/a>.<\/p>\n<p>Importantly, however, that outcome was only found among people with a specific <a href=\"https:\/\/www.sciencealert.com\/alzheimers-risk-gene-alters-brain-activity-early-but-it-may-be-reversible\" rel=\"nofollow noopener\" target=\"_blank\">APOE4 gene variant<\/a>, which is strongly associated with  <a href=\"https:\/\/www.sciencealert.com\/go\/IaO\" class=\"lar_link lar_link_outgoing\" data-linkid=\"73015\" data-postid=\"197899\" rel=\"nofollow noopener\" target=\"_self\">Alzheimer&#8217;s<\/a> disease risk.<\/p>\n<p>Tracking 2,157 over-60s for up to 15 years, researchers at Karolinska Institutet and Stockholm University in Sweden charted the participants&#8217; self-reported diets against their <a href=\"https:\/\/www.sciencealert.com\/new-test-could-tell-if-you-have-early-signs-of-dementia-with-high-accuracy\" target=\"_blank\" rel=\"noopener nofollow\">cognitive test scores<\/a> and any dementia diagnoses.<\/p>\n<p>Plenty of studies have warned about the negative health impacts <a href=\"https:\/\/www.sciencealert.com\/experts-call-for-urgent-action-as-ultra-processed-foods-replace-global-diets\" target=\"_blank\" rel=\"noopener nofollow\">of<\/a><a href=\"https:\/\/www.sciencealert.com\/experts-call-for-urgent-action-as-ultra-processed-foods-replace-global-diets\" rel=\"nofollow noopener\" target=\"_blank\"> processed food<\/a>, and there was evidence for it here, too.<\/p>\n<p>&#8220;A lower proportion of processed meat in total meat consumption was associated with a lower risk of dementia regardless of APOE genotype,&#8221; <a href=\"https:\/\/news.ki.se\/high-meat-consumption-linked-to-lower-dementia-risk-in-genetic-risk-group\" rel=\"nofollow noopener\" target=\"_blank\">says<\/a> Karolinska Institutet neurologist Sara Garcia-Ptacek.<\/p>\n<p>The researchers <a href=\"https:\/\/doi.org\/10.1001\/jamanetworkopen.2026.6489\" rel=\"nofollow noopener\" target=\"_blank\">describe<\/a> APOE4 as the &#8220;ancestral human form&#8221; of the APOE gene, which helped inspire the hypothesis that the brains of people carrying either one or two copies of the variant might respond differently to a meat-heavy diet.<\/p>\n<p>But it&#8217;s important to note that the very idea that our ancestors ate more meat <a href=\"https:\/\/www.sciencealert.com\/not-all-paleolithic-hunter-gatherers-were-big-into-meat-new-study-reveals\" rel=\"nofollow noopener\" target=\"_blank\">has recently<\/a> <a href=\"https:\/\/www.sciencealert.com\/paleo-diet-debunked-ancient-humans-ate-plants-study-shows\" rel=\"nofollow noopener\" target=\"_blank\">been called into question<\/a>.<\/p>\n<p>What&#8217;s more, decades of research, especially on <a href=\"https:\/\/www.sciencealert.com\/decades-long-study-links-red-meat-to-up-to-13-higher-dementia-risk\" rel=\"nofollow noopener\" target=\"_blank\">processed red meat<\/a>, have linked higher meat intake to increased dementia risk, so there&#8217;s reason to remain skeptical until more studies are conducted.<\/p>\n<p>This new study adds some nuance \u2013 and is a reminder that we&#8217;re all built differently, and exposed to different environments.<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/www.newsbeep.com\/us\/wp-content\/uploads\/2026\/04\/GeneChart.jpg\" alt=\"Gene chart\" width=\"642\" height=\"410\" class=\"wp-image-197902 size-full\"   loading=\"lazy\"\/>The researchers tracked the emergence of the APOE gene variants through time. (Norgren et al., JAMA Netw. Open, 2026)<\/p>\n<p>&#8220;This study tested the hypothesis that people with [APOE4] would have a reduced risk of cognitive decline and dementia with higher meat intake,&#8221; <a href=\"https:\/\/news.ki.se\/high-meat-consumption-linked-to-lower-dementia-risk-in-genetic-risk-group\" rel=\"nofollow noopener\" target=\"_blank\">says<\/a> Karolinska Institutet gerontologist Jakob Norgren.<\/p>\n<p>That hypothesis was backed up by the observational data. The participants with APOE4 who <a href=\"https:\/\/www.sciencealert.com\/study-finds-meat-eaters-are-more-likely-to-live-to-100-but-theres-a-catch\" rel=\"nofollow noopener\" target=\"_blank\">ate the most meat<\/a> were significantly less likely to develop dementia, the data showed, while memory decline happened more slowly.<\/p>\n<p>Processed meat accounted for about a third of total meat intake in this cohort&#8217;s diet. The findings suggest that in some cases, eating meat, even red meat, may be good for the brain.<\/p>\n<p>While it&#8217;s not yet clear why the newly observed link exists, it does suggest the relationship between diet and dementia risk may not be the same for everyone. The researchers think that people with APOE4 may absorb certain nutrients <a href=\"https:\/\/www.sciencealert.com\/meat-protects-against-cancer-suggests-controversial-study-heres-the-catch\" rel=\"nofollow noopener\" target=\"_blank\">from meat <\/a>differently.<\/p>\n<p>For those who weren&#8217;t carrying APOE4, meat-eating overall wasn&#8217;t linked to cognitive test scores or the likelihood of dementia developing.<\/p>\n<p>However, the type of meat still made a difference: A higher unprocessed-to-total meat ratio, such as consuming more red meat or poultry, was associated with a lower risk of dementia, regardless of APOE status, compared with higher consumption of processed meat.<\/p>\n<p><a href=\"https:\/\/www.sciencealert.com\/newsletter?utm_source=promo_generic_health\" rel=\"nofollow noopener\" target=\"_blank\"><img decoding=\"async\" src=\"https:\/\/www.newsbeep.com\/us\/wp-content\/uploads\/2026\/03\/Generic-Health-Promo-Final-642x273.jpg\" alt=\"Subscribe to ScienceAlert's free fact-checked newsletter\" width=\"642\" height=\"273\" class=\"alignnone wp-image-182810 size-medium\"   loading=\"lazy\"\/><\/a><\/p>\n<p>The APOE gene encodes <a href=\"https:\/\/en.wikipedia.org\/wiki\/Apolipoprotein_E\" target=\"_blank\" rel=\"noopener nofollow\">apolipoprotein E<\/a>, a protein that helps transport cholesterol and fats throughout the body, including the brain, which may help explain the connection <a href=\"https:\/\/www.sciencealert.com\/new-genetic-form-of-alzheimers-identified-in-people-with-common-risk-factor\" rel=\"nofollow noopener\" target=\"_blank\">between APOE4 and Alzheimer&#8217;s<\/a>. That&#8217;s another association that needs more research to be fully understood.<\/p>\n<p>This is an observational study \u2013 meaning the researchers tracked what people were already eating and how their cognition changed over time, but they did not assign diets experimentally.<\/p>\n<p>The findings reveal an association between meat and <a href=\"https:\/\/www.sciencealert.com\/major-study-links-15-factors-to-early-dementia-risk\" rel=\"nofollow noopener\" target=\"_blank\">dementia risk<\/a>, but do not prove that eating more meat prevents dementia.<\/p>\n<p>For now, the study suggests that people with the APOE4 gene variant \u2013 around a quarter of the global population \u2013 may be able to reduce their dementia risk in different ways.<\/p>\n<p>Related: <a href=\"https:\/\/www.sciencealert.com\/this-unique-diet-could-slow-your-brain-aging-by-over-2-years-study-suggests\" rel=\"nofollow noopener\" target=\"_blank\">This Unique Diet Could Slow Your Brain Aging by Over 2 Years, Study Suggests<\/a><\/p>\n<p>&#8221; <a href=\"https:\/\/www.sciencealert.com\/clinical-trials\" class=\"lar_link lar_link_outgoing\" data-linkid=\"73032\" data-postid=\"197899\" rel=\"nofollow noopener\" target=\"_self\">Clinical trials<\/a> are now needed to develop dietary recommendations tailored to APOE genotype,&#8221; <a href=\"https:\/\/news.ki.se\/high-meat-consumption-linked-to-lower-dementia-risk-in-genetic-risk-group\" rel=\"nofollow noopener\" target=\"_blank\">says<\/a> Norgren.<\/p>\n<p>The research has been published in <a href=\"https:\/\/doi.org\/10.1001\/jamanetworkopen.2026.6489\" rel=\"nofollow noopener\" target=\"_blank\">JAMA Network Open<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"A surprising new observational study has found a tentative connection between eating more meat of any kind and&hellip;\n","protected":false},"author":2,"featured_media":583686,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[34],"tags":[97,1352],"class_list":["post-583685","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-health","tag-msft-content"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/583685","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/comments?post=583685"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/583685\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media\/583686"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media?parent=583685"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/categories?post=583685"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/tags?post=583685"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}