{"id":588550,"date":"2026-04-16T22:24:09","date_gmt":"2026-04-16T22:24:09","guid":{"rendered":"https:\/\/www.newsbeep.com\/us\/588550\/"},"modified":"2026-04-16T22:24:09","modified_gmt":"2026-04-16T22:24:09","slug":"interstellar-travel-may-be-a-real-possibility-because-scientists-successfully-revived-a-frozen-brain","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us\/588550\/","title":{"rendered":"Interstellar Travel May Be a Real Possibility\u2014Because Scientists Successfully Revived a Frozen Brain"},"content":{"rendered":"<p><img src=\"https:\/\/www.popularmechanics.com\/_assets\/design-tokens\/fre\/static\/icons\/clock-regular.4ddebeb.svg\" alt=\"Estimated read time\" width=\"16\" height=\"16\" decoding=\"async\" loading=\"lazy\"\/>5 min read<\/p>\n<p data-journey-content=\"true\" data-node-id=\"1\" class=\"css-6wxqfj emevuu60\">Here\u2019s what you\u2019ll learn when you read this story\u2026<\/p>\n<p>In a groundbreaking study, researchers found that frozen tissue from mouse brains could return to normal functions after facing extremely cold conditions.The findings suggest that brain tissue is significantly more resilient than previously believed.According to experts, there is still a ways to go before we engineer any sort of \u201chuman hibernation\u201d\u2014but this may be a step in the right direction.<\/p>\n<p data-journey-content=\"true\" data-node-id=\"4\" class=\"body-dropcap css-1im7l9i emevuu60\">If we want to travel to distant stars like Alpha Centauri, we\u2019ll have to drastically rethink how humans operate in <a rel=\"nofollow noopener\" href=\"https:\/\/www.popularmechanics.com\/space\/a70922664\/wormholes-quantum-spacetime\/\" target=\"_blank\" data-vars-ga-outbound-link=\"https:\/\/www.popularmechanics.com\/space\/a70922664\/wormholes-quantum-spacetime\/\" data-vars-ga-ux-element=\"Hyperlink\" data-vars-ga-call-to-action=\"space\" data-node-id=\"4.2\" class=\"body-link css-vxmlos emevuu60\">space<\/a>. How will we store all the food and water we\u2019ll need? And could some kind of human hibernation bring astronauts to deep space\u2014without killing them\u2014as seen in the recent box office hit Project Hail Mary?<\/p>\n<p data-journey-content=\"true\" data-node-id=\"5\" class=\"css-6wxqfj emevuu60\">This kind of \u201ccryosleep\u201d has mostly been relegated to the world of science fiction\u2014that is, until now. A <a rel=\"nofollow noopener\" href=\"https:\/\/www.pnas.org\/doi\/10.1073\/pnas.2516848123\" target=\"_blank\" data-vars-ga-outbound-link=\"https:\/\/www.pnas.org\/doi\/10.1073\/pnas.2516848123\" data-vars-ga-ux-element=\"Hyperlink\" data-vars-ga-call-to-action=\"new study\" data-node-id=\"5.1\" class=\"body-link css-vxmlos emevuu60\">new study<\/a> published in the Proceedings of the National Academy of Sciences showed it might just be possible (at least in slices of <a rel=\"nofollow noopener\" href=\"https:\/\/www.popularmechanics.com\/science\/a70974233\/consciousness-of-assembloids\/\" target=\"_blank\" data-vars-ga-outbound-link=\"https:\/\/www.popularmechanics.com\/science\/a70974233\/consciousness-of-assembloids\/\" data-vars-ga-ux-element=\"Hyperlink\" data-vars-ga-call-to-action=\"brain\" data-node-id=\"5.5\" class=\"body-link css-vxmlos emevuu60\">brain<\/a> tissue from mice). This could be groundbreaking for the prospect of human interstellar travel. Still, there is far more research that scientists must conduct before we can translate these findings from <a rel=\"nofollow noopener\" href=\"https:\/\/www.popularmechanics.com\/science\/health\/a70172357\/human-organoids-rat-brains\/\" target=\"_blank\" data-vars-ga-outbound-link=\"https:\/\/www.popularmechanics.com\/science\/health\/a70172357\/human-organoids-rat-brains\/\" data-vars-ga-ux-element=\"Hyperlink\" data-vars-ga-call-to-action=\"rodents\" data-node-id=\"5.7\" class=\"body-link css-vxmlos emevuu60\">rodents<\/a> to people.<\/p>\n<p data-journey-content=\"true\" data-node-id=\"7\" class=\"css-6wxqfj emevuu60\">In their study, the scientists were essentially aiming to solve a hypothesis: Can adult mammal brain tissue recover after a specific process puts the tissue into a cryogenic, or extremely low temperature, state? That requires a process called vitrification, in which you use water to cool something\u2014like brain tissue\u2014so rapidly that its molecules stop moving. Vitrification is already used to harvest human eggs for fertility treatments. This means scientists already have a working foundation to build off of when testing other parts of the body in cryogenic states.<\/p>\n<p data-journey-content=\"true\" data-node-id=\"8\" class=\"css-6wxqfj emevuu60\">So, the team of German scientists ran an experiment on mice\u2019s hippocampal tissue\u2014the part of the brain associated with memory and learning. The researchers wanted to see if the brain\u2019s cells, called neurons, could resume normal activity after it was cooled to minus 196 degrees Celsius. They primarily experimented on slices of mouse brain, but also tested the resilience of the whole organ. The takeaway?<\/p>\n<p data-journey-content=\"true\" data-node-id=\"9\" class=\"css-6wxqfj emevuu60\">\u201cAdult mouse hippocampal tissue can indeed recover after rewarming,\u201d says <a rel=\"nofollow noopener\" href=\"https:\/\/www.dzi.uk-erlangen.de\/en\/contact\/buisness-card\/?tx_app_contact%5Baction%5D=show&amp;tx_app_contact%5Bcontact%5D=12102&amp;tx_app_contact%5Bcontroller%5D=Contact&amp;cHash=acdd4a2425e1a76fb29b298a8d9e2cbf\" target=\"_blank\" data-vars-ga-outbound-link=\"https:\/\/www.dzi.uk-erlangen.de\/en\/contact\/buisness-card\/?tx_app_contact%5Baction%5D=show&amp;tx_app_contact%5Bcontact%5D=12102&amp;tx_app_contact%5Bcontroller%5D=Contact&amp;cHash=acdd4a2425e1a76fb29b298a8d9e2cbf\" data-vars-ga-ux-element=\"Hyperlink\" data-vars-ga-call-to-action=\"Alexander German\" data-node-id=\"9.1\" class=\"body-link css-vxmlos emevuu60\">Alexander German<\/a>, MD, lead author of the study and a clinician scientist at Germany\u2019s University Hospital Erlangen.<\/p>\n<p data-journey-content=\"true\" data-node-id=\"10\" class=\"css-6wxqfj emevuu60\">Slices of this part of the mouse brain not only had \u201cstructural integrity\u201d after freezing, but the neurons and synapses needed for learning and memory also appeared to be functioning. German says there were also recovery signals in the whole mouse brain, but \u201cthat part is still much less mature than the slice work.\u201d<\/p>\n<p data-journey-content=\"true\" data-node-id=\"11\" class=\"css-6wxqfj emevuu60\">The findings from the study were a massive leap forward, as they show that the tolerance of brain tissue now extends beyond hypothermic (very cold) to cryogenic (extreme cold) states. But to approach humans, we still need to close a major knowledge gap.<\/p>\n<p>If hibernation could be induced, no matter the process, \u201cit would be good for a number of uses, including space travel.\u201d<\/p>\n<p data-journey-content=\"true\" data-node-id=\"13\" class=\"css-6wxqfj emevuu60\">So, how close are we to cryosleep exactly? <a rel=\"nofollow noopener\" href=\"https:\/\/medschool.cuanschutz.edu\/cell-and-developmental-biology\/faculty\/sandy-martin\" target=\"_blank\" data-vars-ga-outbound-link=\"https:\/\/medschool.cuanschutz.edu\/cell-and-developmental-biology\/faculty\/sandy-martin\" data-vars-ga-ux-element=\"Hyperlink\" data-vars-ga-call-to-action=\"Sandy Martin\" data-node-id=\"13.1\" class=\"body-link css-vxmlos emevuu60\">Sandy Martin<\/a>, PhD, a professor emerita at the University of Colorado Anschutz, says she is unable to comment on the process of vitrification in humans specifically. But she claims scientists are making general progress in learning what mechanisms might induce hibernation in humans.<\/p>\n<p data-journey-content=\"true\" data-node-id=\"14\" class=\"css-6wxqfj emevuu60\">Martin, who has studied hibernation in mammals for decades, emphasizes that we don\u2019t have the tools yet for humans. But in hibernating animals, researchers are learning more about how they slow down the body metabolically with the hypothalamus, the part of the brain that manages the body\u2019s temperature.<\/p>\n<p data-journey-content=\"true\" data-node-id=\"15\" class=\"css-6wxqfj emevuu60\">Hibernation can vary by species. Martin says some hibernators, such as ground squirrels, rewarm\u2014or wake up from hibernation from internal heating, rather than with the help of warm weather. This rewarming takes place even with no changes in the environment, so something internally must be driving it.<\/p>\n<p data-journey-content=\"true\" data-node-id=\"16\" class=\"css-6wxqfj emevuu60\">The rewarming and cooling down again, Martin says, is \u201cenergetically, incredibly demanding. It is a time where [squirrels] have little oxygen delivery, because their blood is slow and sluggish. It\u2019s cold, and yet their tissues are demanding a great deal of oxygen.\u201d What\u2019s more, the animals successfully warm up and cool down without harming their tissues. \u201cWhatever damage occurs, they\u2019re able to fix it,\u201d she continues.<\/p>\n<p data-journey-content=\"true\" data-node-id=\"17\" class=\"css-6wxqfj emevuu60\">There\u2019s interest as well in studying hibernation in fat-tailed dwarf lemurs\u2014which, like humans, are primates. It appears the dwarf lemurs don\u2019t need to rewarm during hibernation. But studying the lemurs is a challenge, because the species <a rel=\"nofollow noopener\" href=\"https:\/\/neprimateconservancy.org\/fat-tailed-dwarf-lemur\/\" target=\"_blank\" data-vars-ga-outbound-link=\"https:\/\/neprimateconservancy.org\/fat-tailed-dwarf-lemur\/\" data-vars-ga-ux-element=\"Hyperlink\" data-vars-ga-call-to-action=\"is vulnerable\" data-node-id=\"17.1\" class=\"body-link css-vxmlos emevuu60\">is vulnerable<\/a> (a classification referring to their risk of extinction in the wild) and thus presents ethical issues for study, Martin explains.<\/p>\n<p data-journey-content=\"true\" data-node-id=\"18\" class=\"css-6wxqfj emevuu60\">German, the vitrification study lead author, also pointed to the effort required to push forward vitrification research in humans. There is proof-of-concept that the human cortex (the outermost layer of the brain) could regain normal function after freezing, German says. But applied to the whole body? \u201cThe gap is still enormous,\u201d he says. He points specifically to issues like creating better cooling and rewarming methods for large volumes of tissues, and \u201cvalidation in larger animal models\u201d over longer observation periods.<\/p>\n<p data-journey-content=\"true\" data-node-id=\"19\" class=\"css-6wxqfj emevuu60\">There are small signs of progress. A spinoff company German recently co-founded, called Hiber, aims to bring post-death brain preservation to human neural tissue, as a sort of \u201cbiological archive\u201d for future research. The startup is in the early stages of cryopreserving the human heart, another complex organ, with the hope that one day that process could be used for organ transplants.<\/p>\n<p data-journey-content=\"true\" data-node-id=\"21\" class=\"css-6wxqfj emevuu60\">So could astronauts one day be frozen in stasis using vitrification? German says not to necessarily count on it, but the \u201cfirst principles\u201d of suspending a human organism\u2019s normal processes for a while could be useful. \u201cOur work supports [human hibernation] in a very limited sense,\u201d he explains. \u201cIf something becomes practical sooner, it may well be milder, torpor-like states rather than whole-body vitrification.\u201d<\/p>\n<p data-journey-content=\"true\" data-node-id=\"22\" class=\"css-6wxqfj emevuu60\">Martin adds that if hibernation could be induced, no matter the process, \u201cit would be good for a number of uses, including space travel.\u201d But to get there, she says we will need research funding over a sustained period. She brought up HIV research as an analogy: it took about 20 years and \u201ctons of money\u201d (at least <a rel=\"nofollow noopener\" href=\"https:\/\/www.oar.nih.gov\/sites\/default\/files\/NIH_StrategicPlan_FY2021-2025.pdf\" target=\"_blank\" data-vars-ga-outbound-link=\"https:\/\/www.oar.nih.gov\/sites\/default\/files\/NIH_StrategicPlan_FY2021-2025.pdf\" data-vars-ga-ux-element=\"Hyperlink\" data-vars-ga-call-to-action=\"billions\" data-node-id=\"22.1\" class=\"body-link css-vxmlos emevuu60\">billions<\/a> from the National Institutes of Health alone) to find ways to manage the condition.<\/p>\n<p data-journey-content=\"true\" data-node-id=\"23\" class=\"css-6wxqfj emevuu60\">While we don\u2019t yet know how to induce hibernation in people, there\u2019s hope that related research could one day help astronauts travel long distances. But this will also bring up broader questions about whether it\u2019s worth it, or whether it would just be simpler to send machines in our stead\u2014allowing us to focus medical research dollars elsewhere.<\/p>\n<p>Download Pop Mech Digital Issues<img decoding=\"async\" data-dynamic-svg=\"true\" src=\"https:\/\/www.popularmechanics.com\/_assets\/design-tokens\/fre\/static\/icons\/arrow-left-regular.dc4f48a.svg?primary=%2523D4D4D4\" loading=\"lazy\" data-testid=\"dynamic-svg-base\" height=\"auto\" width=\"auto\" aria-label=\"Prev carousel button\" alt=\"Chevron Left Icon\" data-theme-key=\"icon-button-icon\" class=\"css-18znc9e erhb41k0\"\/><img decoding=\"async\" data-dynamic-svg=\"true\" src=\"https:\/\/www.popularmechanics.com\/_assets\/design-tokens\/fre\/static\/icons\/arrow-right-regular.e879c19.svg?primary=%2523fff\" loading=\"lazy\" data-testid=\"dynamic-svg-base\" height=\"auto\" width=\"auto\" aria-label=\"Next carousel button\" alt=\"Chevron Right Icon\" data-theme-key=\"icon-button-icon\" class=\"css-18znc9e erhb41k0\"\/><img src=\"https:\/\/www.newsbeep.com\/us\/wp-content\/uploads\/2026\/04\/245cdfcf-c364-4f16-9c45-e17af73526e3_1758200726.file.png\" alt=\"Headshot of Elizabeth Howell\" title=\"Headshot of Elizabeth Howell\" width=\"100%\" height=\"100%\" decoding=\"async\" loading=\"lazy\" class=\"css-o0wq4v ev8dhu53\"\/><\/p>\n<p>Elizabeth Howell (Ph.D., she\/her) is one of a few space journalists in Canada. She has written five books, and was Space.com&#8217;s former staff reporter in spaceflight. As a freelancer, she has written or edited articles about astronomy and space exploration for outlets such as Payload Space, Air&amp;Space Magazine, Sky &amp; Telescope and Salon. Elizabeth holds university degrees in journalism, science and history and also teaches an astronomy course, with Indigenous content, at Canada&#8217;s Algonquin College. Aside from watching several astronaut missions launching from Florida and Kazakhstan, Elizabeth once lived like an astronaut at the Mars Society&#8217;s Mars Desert Research Station in Utah.\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"5 min read Here\u2019s what you\u2019ll learn when you read this story\u2026 In a groundbreaking study, researchers found&hellip;\n","protected":false},"author":2,"featured_media":588551,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[32],"tags":[88551,79],"class_list":{"0":"post-588550","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-science","8":"tag-88551","9":"tag-science"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/588550","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/comments?post=588550"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/588550\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media\/588551"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media?parent=588550"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/categories?post=588550"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/tags?post=588550"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}