{"id":605183,"date":"2026-04-25T07:26:14","date_gmt":"2026-04-25T07:26:14","guid":{"rendered":"https:\/\/www.newsbeep.com\/us\/605183\/"},"modified":"2026-04-25T07:26:14","modified_gmt":"2026-04-25T07:26:14","slug":"cancer-cells-have-an-achilles-heel-they-can-be-starved-to-death","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us\/605183\/","title":{"rendered":"Cancer cells have an Achilles heel, they can be starved to death"},"content":{"rendered":"<p>Quick summary &#8211; click for full details<\/p>\n<p>Concise summary of key highlights<\/p>\n<p>In one line<\/p>\n<p>Unlike normal cells, malignant or cancer cells are incapable of having a healthy metabolism and often look for substitute fuels and less efficient metabolic pathways to thrive.<\/p>\n<p>Key points<\/p>\n<p>\u2022 Metabolic instability in cancer<\/p>\n<p>Cancer cells rely on inefficient metabolic pathways like fermentation due to their inability to use oxygen for energy, making them vulnerable to dietary interventions.<\/p>\n<p>\u2022 Primary energy sources<\/p>\n<p>Cancer cells depend heavily on glucose and glutamine for survival and growth, which can be removed to starve them.<\/p>\n<p>\u2022 Mitochondrial role in cancer<\/p>\n<p>Malfunctioning mitochondria in cancer cells spread metabolic dysfunction, driving cancer progression and spread.<\/p>\n<p>\u2022 Biotin dependency<\/p>\n<p>Cancer cells require Vitamin B7 (biotin) to bypass glutamine scarcity, and cutting biotin supply can stunt their growth.<\/p>\n<p>\u2022 Metabolic theory of cancer<\/p>\n<p>The Metabolic Theory of Cancer, supported by Warburg\u2019s findings, redefines cancer as a metabolic disease, offering new treatment avenues.<\/p>\n<p>Processed with AI. Reviewed by DH Digital Team.<\/p>\n<p>Published 24 April 2026, 12:07 IST<\/p>\n","protected":false},"excerpt":{"rendered":"Quick summary &#8211; click for full details Concise summary of key highlights In one line Unlike normal cells,&hellip;\n","protected":false},"author":2,"featured_media":605184,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[34],"tags":[263094,263080,263079,263093,52229,263084,101529,263087,195309,43711,263085,263088,29791,263075,263090,263076,97,263077,263095,263074,263083,263078,263092,263086,263091,263081,263089,263082],"class_list":["post-605183","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-alternative-pathways","tag-atp-generation","tag-biotin-deficiency","tag-biotin-deprivation","tag-cancer-cells","tag-cancer-energy-production","tag-cancer-metabolism","tag-cancer-spread","tag-cancer-survival","tag-cancer-treatment","tag-cellular-science","tag-dietary-treatment","tag-genetic-factors","tag-glucose-dependency","tag-glutamine-addiction","tag-glutamine-and-cancer","tag-health","tag-metabolic-shortcut","tag-metabolic-substrates","tag-metabolic-theory","tag-metabolic-weakness","tag-mitochondrial-dysfunction","tag-mitochondrial-enzyme","tag-mitochondrial-role","tag-pyruvate-carboxylase","tag-thomas-seyfried","tag-vitamin-b7","tag-warburg-theory"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/605183","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/comments?post=605183"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/605183\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media\/605184"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media?parent=605183"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/categories?post=605183"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/tags?post=605183"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}