{"id":606097,"date":"2026-04-25T18:50:18","date_gmt":"2026-04-25T18:50:18","guid":{"rendered":"https:\/\/www.newsbeep.com\/us\/606097\/"},"modified":"2026-04-25T18:50:18","modified_gmt":"2026-04-25T18:50:18","slug":"vitamin-b12-study-shows-diet-can-shape-inheritance","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us\/606097\/","title":{"rendered":"Vitamin B12 study shows diet can shape inheritance"},"content":{"rendered":"<p>Scientists have found that vitamin B12 can cause worms to develop a meat-eating mouth shape that their offspring inherit without changes to their DNA.<\/p>\n<p>The discovery turns a common nutrient into a biological signal, linking diet to inheritance across generations.<\/p>\n<p>Evidence in worms<br \/>\n<a href=\"https:\/\/earthsnap.onelink.me\/3u5Q\/ags2loc4\" rel=\"noopener nofollow\" target=\"_blank\">&#13;<br \/>\n    <img decoding=\"async\" class=\"fit-picture\" loading=\"lazy\" src=\"https:\/\/www.newsbeep.com\/us\/wp-content\/uploads\/2026\/01\/1767702488_540_earthsnap-banner-news.webp.webp\" alt=\"EarthSnap\"\/>&#13;<br \/>\n<\/a><\/p>\n<p>In laboratory lines of Pristionchus pacificus, the finding appeared in mouthparts that either stayed narrow or became predatory.<\/p>\n<p>Tracking those forms across generations, Shiela Pearl Quiobe at the Max Planck Institute for Biology T\u00fcbingen (<a href=\"https:\/\/www.bio.mpg.de\/2923\/en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">MPI<\/a>) documented vitamin B12 as the factor tied to inherited predation.<\/p>\n<p>The change did not end with the worms that consumed the vitamin, but continued after later generations returned to ordinary food.<\/p>\n<p>That persistence focused attention on what mothers passed forward, linking diet and inheritance through nutrients stored in eggs.<\/p>\n<p>How B12 alters traits<\/p>\n<p>Vitamin B12 made the predatory mouth form appear quickly when worms ate bacteria or supplemented food on treated plates.<\/p>\n<p>In high enough amounts, the vitamin kept that form showing up after the animals returned to ordinary food.<\/p>\n<p>Lower amounts still started the predatory shape, yet the inherited effect faded after one or two generations once food changed.<\/p>\n<p>\u201cOur findings show that vitamin <a href=\"https:\/\/www.earth.com\/video\/skip-the-salmon-and-eat-these-fish\/\" rel=\"nofollow noopener\" target=\"_blank\">B12<\/a> does not simply affect the individual consuming it, but can shape the biology of future generations,\u201d said Quiobe.<\/p>\n<p>Bacteria supplied signals<\/p>\n<p>A bacterium called Novosphingobium pushed worms toward predation because it supplied vitamin B12 and other food signals.<\/p>\n<p>When scientists used bacteria unable to make the vitamin, descendants lost the inherited predatory pattern as soon as food switched.<\/p>\n<p>Adding vitamin B12 back restored that carryover, while the defective bacteria still partly shaped the first <a href=\"https:\/\/www.earth.com\/news\/rice-could-help-create-the-next-generation-of-dairy-free-cheese\/\" rel=\"nofollow noopener\" target=\"_blank\">generation<\/a>.<\/p>\n<p>Other bacterial chemicals can help build the mouthparts, but vitamin B12 carried the lasting signal over time.<\/p>\n<p>Nutrients stored in eggs<\/p>\n<p>Mothers passed the effect through vitellogenin, a yolk protein that feeds embryos, rather than through vitamin B12 itself.<\/p>\n<p>Vitamin-rich diets raised vitellogenin gene activity, which packed more nutritional support into eggs before development began across generations.<\/p>\n<p>Worms missing the egg uptake system could become <a href=\"https:\/\/www.earth.com\/news\/fossil-find-polycotylus-plesiosaur-taken-out-by-bigger-predatory-fish-xiphactinus-alabama\/\" rel=\"nofollow noopener\" target=\"_blank\">predatory<\/a>, but their offspring lost the pattern in the next generation.<\/p>\n<p>The result places egg contents alongside DNA sequence as part of inherited change across generations.<\/p>\n<p>Genes remain unchanged<\/p>\n<p>The worms inherited a behavior-linked mouth form without a DNA rewrite, giving the finding its strongest point.<\/p>\n<p>Biologists call such carryover epigenetic inheritance, when conditions affect descendants without directly changing genetic letters after one generation ends.<\/p>\n<p>Earlier famine <a href=\"https:\/\/www.pnas.org\/doi\/10.1073\/pnas.0806560105\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">research<\/a> in humans found lasting DNA marking differences after prenatal exposure, but mechanisms remain difficult to separate.<\/p>\n<p>Worm experiments give scientists a cleaner cause-and-effect path about diet, while keeping human claims out of reach.<\/p>\n<p>Dose determines outcome<\/p>\n<p>At very small amounts, added vitamin B12 preserved predatory memory after worms left rich food.<\/p>\n<p>With moderate amounts, the animals still formed predatory mouths, but the carryover stopped short of true inheritance after the vitamin disappeared.<\/p>\n<p>Even trace amounts could trigger the mouth change, while extremely low amounts left worms near their usual state under the same setup.<\/p>\n<p>Dose mattered because the first response was easy to start, but memory required more vitamin across generations.<\/p>\n<p>Amino acid role found<\/p>\n<p>Cells needed methionine, an amino acid used in protein building, for the vitamin signal to continue.<\/p>\n<p>Supplements of methionine slowly produced the meat-eating mouth shape and maintained the pattern for several later generations after repeated exposures.<\/p>\n<p>By contrast, folate \u2013 another B vitamin involved in cell chemistry \u2013 did not create a clear predatory response under these tests.<\/p>\n<p>That contrast points to a specific route inside cells, not a general effect of richer food or plate conditions.<\/p>\n<p>Predation in the wild<\/p>\n<p>Long before this vitamin test, the Max Planck group followed 110 <a href=\"https:\/\/www.science.org\/doi\/10.1126\/sciadv.adu0875\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">groups<\/a> of genetically similar worms across 101 generations on different diets.<\/p>\n<p>That earlier work showed predatory mouthparts persisted only after at least five generations on the bacterial diet before lines switched back.<\/p>\n<p>In nature, these worms often ride beetles and face crowded food after insects die in soil once they arrive.<\/p>\n<p>A remembered predatory form could help descendants compete when bacteria, fungi, and other worms share one carcass during that brief period.<\/p>\n<p>Human relevance limited<\/p>\n<p>Humans also need <a href=\"https:\/\/ods.od.nih.gov\/factsheets\/VitaminB12-HealthProfessional\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">vitamin B12<\/a> for nerves, blood cells, and DNA maintenance, but this worm result is not medical advice.<\/p>\n<p>During pregnancy and early childhood, B12 supports growth because dividing cells need it to handle key chemical reactions.<\/p>\n<p>No human research has shown that B12 programs inherited traits in people through this worm pathway.<\/p>\n<p>Still, the finding sharpens a broader lesson: nutrition can alter biology beyond a single lifetime for some animals.<\/p>\n<p>Next steps in study<\/p>\n<p>By tying diet, bacterial chemistry, egg nutrition, and inherited behavior into one chain, the work gives a rare clean example.<\/p>\n<p>Future tests should measure memory length through offspring and identify other nutrients that produce similar effects in controlled lineages.<\/p>\n<p>The study is published in <a href=\"https:\/\/www.nature.com\/articles\/s41467-026-71494-w\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Nature Communications<\/a>.<\/p>\n<p>\u2014\u2013<\/p>\n<p>Like what you read?\u00a0<a href=\"https:\/\/www.earth.com\/subscribe\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Subscribe to our newsletter<\/a>\u00a0for engaging articles, exclusive content, and the latest updates.<\/p>\n<p>Check us out on\u00a0<a href=\"https:\/\/www.earth.com\/earthsnap\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">EarthSnap<\/a>, a free app brought to you by\u00a0<a href=\"https:\/\/www.earth.com\/author\/eralls\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Eric Ralls<\/a>\u00a0and Earth.com.<\/p>\n<p>\u2014\u2013<\/p>\n","protected":false},"excerpt":{"rendered":"Scientists have found that vitamin B12 can cause worms to develop a meat-eating mouth shape that their offspring&hellip;\n","protected":false},"author":2,"featured_media":606098,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[61],"tags":[97,269],"class_list":{"0":"post-606097","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-nutrition","8":"tag-health","9":"tag-nutrition"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/606097","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/comments?post=606097"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/606097\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media\/606098"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media?parent=606097"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/categories?post=606097"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/tags?post=606097"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}