{"id":621407,"date":"2026-05-03T17:32:10","date_gmt":"2026-05-03T17:32:10","guid":{"rendered":"https:\/\/www.newsbeep.com\/us\/621407\/"},"modified":"2026-05-03T17:32:10","modified_gmt":"2026-05-03T17:32:10","slug":"california-researchers-devise-treatment-for-deadly-pregnancy-condition","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us\/621407\/","title":{"rendered":"California researchers devise treatment for deadly pregnancy condition"},"content":{"rendered":"<p><img alt=\"There\u2019s no cure for women with preeclampsia other than giving birth.\u00a0\" loading=\"eager\" fetchpriority=\"high\"   style=\"aspect-ratio:3 \/ 2\" class=\"x100 y100 opc bgpc ofcv bgscv block bg-gray200 mnh0px fill\"\/><\/p>\n<p>There\u2019s no cure for women with preeclampsia other than giving birth.\u00a0<\/p>\n<p>SDI Productions\/Getty<\/p>\n<p>For <a href=\"https:\/\/www.sfgate.com\/health\/article\/Preeclampsia-a-leading-cause-of-pregnancy-related-5204974.php\" data-link=\"native\" class=\"\" rel=\"nofollow noopener\" target=\"_blank\">decades<\/a>, the medical community has searched for a cure for one of the most frightening and mysterious pregnancy complications:\u00a0preeclampsia.\u00a0<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/cdn-channels-pixel.ex.co\/events\/0012000001fxZm9AAE?integrationType=DEFAULT&amp;template=design%2Farticle%2Fplatypus_two_column.tpl\" alt=\"\" class=\"x1px y1px vh abs\" aria-hidden=\"true\" width=\"1\" height=\"1\"\/><\/p>\n<p>The condition is <a href=\"https:\/\/blogs.cdc.gov\/genomics\/2022\/10\/25\/preeclampsia\/\" data-link=\"native\" class=\"\" rel=\"nofollow noopener\" target=\"_blank\">characterized<\/a>\u00a0by high blood pressure and protein in the urine, among other symptoms. If untreated, the condition can progress to eclampsia, a medical emergency that can cause seizures, stroke or death. About 70,000 women and 500,000 fetuses die of the condition every year. Women with the condition can get supportive treatment to lower their blood pressure, but the only real cure is to give birth, and\u00a0the condition may still occur after giving birth.<\/p>\n<p class=\"uiTextSmall f aic jcc\">Article continues below this ad<\/p>\n<p><img alt=\"Researchers at Cedars-Sinai in Los Angeles, among other institutions, created an experimental treatment for preeclampsia.\" loading=\"lazy\"   style=\"aspect-ratio:3 \/ 2\" class=\"x100 y100 opc bgpc ofcv bgscv block bg-gray200 mnh0px fill\"\/><\/p>\n<p>Researchers at Cedars-Sinai in Los Angeles, among other institutions, created an experimental treatment for preeclampsia.<\/p>\n<p>JHVEPhoto\/Getty<\/p>\n<p>And if they have to give birth too early, their <a href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/21479-premature-birth\" data-link=\"native\" class=\"\" rel=\"nofollow noopener\" target=\"_blank\">premature infants<\/a> are at risk of multiple major health conditions, including vision problems, breathing problems, brain swelling and death.<\/p>\n<p>Now, a new study from researchers at\u00a0<a href=\"https:\/\/www.cedars-sinai.org\/newsroom\/study-new-preeclampsia-treatment-may-safely-extend-pregnancy\/\" data-link=\"native\" class=\"\" rel=\"nofollow noopener\" target=\"_blank\">Cedars-Sinai<\/a> in Los Angeles shows the potential of a new treatment that actually targets the cause of preeclampsia. <a href=\"https:\/\/www.nature.com\/articles\/s41591-026-04333-6\" data-link=\"native\" class=\"\" rel=\"nofollow noopener\" target=\"_blank\">Published<\/a>\u00a0in Nature Medicine on April 27, the small study looked at data from 16 women with the condition.\u00a0<\/p>\n<p><a href=\"https:\/\/researchers.cedars-sinai.edu\/SAnanth.Karumanchi?prevPageName=cs-org%3Acedars-sinai%3Anewsroom%3Astudy-new-preeclampsia-treatment-may-safely-extend-pregnancy\" data-link=\"native\" class=\"\" rel=\"nofollow noopener\" target=\"_blank\">Dr. Ananth Karumanchi<\/a>, director of the Renovascular Research Center at Cedars-Sinai and one of the study authors, explained that one hypothesis about why preeclampsia develops is that a malfunctioning placenta produces high amounts of a protein called sFlt-1, with toxic consequences to the body. But developing a drug to target that protein is complicated for a medical community hesitant about testing anything on pregnant women.\u00a0<\/p>\n<p class=\"uiTextSmall f aic jcc\">Article continues below this ad<\/p>\n<p>Make SFGATE a preferred source so your search results prioritize writing by actual people, not AI.<\/p>\n<p><a href=\"https:\/\/www.google.com\/preferences\/source?q=sfgate.com\" data-link=\"native\" role=\"button\" aria-label=\"Add Preferred Source\" class=\"td300 cp f aic jcc disabled:cd wsn px24 y40px px16 py8 buttonSm fs13 xs:fs16 lg:buttonLg bg-primaryAccessible hover:o80 c-white disabled:bg-gray300 disabled:c-gray600 border bn tac br48px\"><\/p>\n<p>Add Preferred Source<\/p>\n<p><\/a><\/p>\n<p>\u201cWhenever you think about giving a medicine into a pregnant woman, you really have to think about not just acute safety for mom and the baby, but more long-term safety,\u201d he said.\u00a0<\/p>\n<p>Karumanchi and researchers from institutions around the globe decided on a \u201csubtraction\u201d approach by taking a page from dialysis treatments. They developed a monoclonal antibody that would in essence bind with the problematic protein. Next, a machine removed blood from patients, filtered out the damaging protein and then returned the blood to the patients.\u00a0<\/p>\n<p>The entire process took about two hours, and Karumanchi said they could see results within hours.\u00a0<\/p>\n<p class=\"uiTextSmall f aic jcc\">Article continues below this ad<\/p>\n<p>In the trial, the protein levels dropped by about 17% in the study individuals after the treatment. Additionally, the lower protein levels correlated with lower blood pressure. Those taking part in the study were able to delay birth for a median of <a href=\"https:\/\/www.cedars-sinai.org\/newsroom\/study-new-preeclampsia-treatment-may-safely-extend-pregnancy\/\" data-link=\"native\" class=\"\" rel=\"nofollow noopener\" target=\"_blank\">10 days<\/a>, double the time for untreated patients.<\/p>\n<p>Karumanchi said the findings are \u201cexciting,\u201d but they\u2019ll need to do more research to make sure it\u2019s a safe and effective treatment.\u00a0<\/p>\n<p>\u201cWe need to do a formal regulatory study \u2026 like a standard, controlled trial, where we do treatment versus no treatment,\u201d he explained.<\/p>\n<p>Dr. Yalda Afshar, an associate professor of Obstetrics and Gynecology at UCLA Health, who was not involved with the study, said although the trial was small, it \u201clays the groundwork\u201d for future research and \u201cflips that script\u201d by targeting the cause of preeclampsia.\u00a0<\/p>\n<p class=\"uiTextSmall f aic jcc\">Article continues below this ad<\/p>\n<p>\u201cThe really big piece about it \u2026 despite being a pilot, is that for the first time, we\u2019re directly removing the disease from that mother,\u201d she told SFGATE by phone; currently, they are forced to \u201cremove the mother from the disease.\u201d\u00a0<\/p>\n<p>Caitlin Dirvonas, a mother of three from Phoenix, has had\u00a0preeclampsia during all three pregnancies. Her first child was born at 27 weeks due to severe preeclampsia and remained in the NICU for 75 days. She told SFGATE that\u00a0a treatment that can help delay a premature delivery even by days could be key.\u00a0<\/p>\n<p>\u201cEvery day at that point, that early on, counts for brain development, for lung development,\u201d she said.\u00a0<\/p>\n<p class=\"uiTextSmall f aic jcc\">Article continues below this ad<\/p>\n","protected":false},"excerpt":{"rendered":"There\u2019s no cure for women with preeclampsia other than giving birth.\u00a0 SDI Productions\/Getty For decades, the medical community&hellip;\n","protected":false},"author":2,"featured_media":621408,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[34],"tags":[97,245653,243150],"class_list":["post-621407","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-health","tag-sfgla","tag-sfgnews"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/621407","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/comments?post=621407"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/621407\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media\/621408"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media?parent=621407"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/categories?post=621407"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/tags?post=621407"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}