{"id":622278,"date":"2026-05-04T04:31:10","date_gmt":"2026-05-04T04:31:10","guid":{"rendered":"https:\/\/www.newsbeep.com\/us\/622278\/"},"modified":"2026-05-04T04:31:10","modified_gmt":"2026-05-04T04:31:10","slug":"immune-cells-leave-memory-of-obesity-after-weight-loss","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us\/622278\/","title":{"rendered":"Immune cells leave \u2018memory\u2019 of obesity after weight loss"},"content":{"rendered":"<p class=\"mb-4 text-lg md:leading-8 break-words\">(<a data-yga=\"{\" ylinkelement=\"\" href=\"https:\/\/www.newsnationnow.com\/\" rel=\"nofollow noopener\" target=\"_blank\" data-ylk=\"elm:link;elmt:article_link;slk:NewsNation;itc:0;sec:content-canvas\" class=\"link \">NewsNation<\/a>) \u2014 A new study suggests <a data-yga=\"{\" ylinkelement=\"\" href=\"https:\/\/www.newsnationnow.com\/health\/health-headlines\/ap-obesity-remains-high-in-the-us-but-more-states-are-showing-progress-a-new-report-finds\/\" rel=\"nofollow noopener\" target=\"_blank\" data-ylk=\"elm:link;elmt:article_link;slk:obesity;itc:0;sec:content-canvas\" class=\"link \">obesity<\/a> may leave a lasting \u201cmemory\u201d on the immune system, even after significant weight loss.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">The research, conducted by scientists at the <a data-yga=\"{\" ylinkelement=\"\" href=\"https:\/\/www.birmingham.ac.uk\/news\/2026\/obesity-leaves-a-lasting-memory-in-immune-cells\" rel=\"nofollow noopener\" target=\"_blank\" data-ylk=\"elm:link;elmt:article_link;slk:University of Birmingham;itc:0;sec:content-canvas\" class=\"link \">University of Birmingham<\/a>, examined how obesity affects immune function over time by analyzing blood and fat tissue samples from several groups, including:<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">People with Alstr\u00f6m syndrome, a rare genetic disorder marked by early\u2011onset childhood obesity, along with healthy matched participants<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">People who took part in a 10\u2011week exercise intervention<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">People of normal weight and those with obesity undergoing hip or knee replacement surgery for osteoarthritis<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\"><a data-yga=\"{\" ylinkelement=\"\" class=\"link \" href=\"https:\/\/www.newsnationnow.com\/health\/lung-cancer-non-smokers-common\/?ipid=promo-link-block1\" rel=\"nofollow noopener\" target=\"_blank\" data-ylk=\"elm:link;elmt:article_link;slk:Lung cancer diagnoses in nonsmokers increasingly common: Author;itc:0;sec:content-canvas\"> Lung cancer diagnoses in nonsmokers increasingly common: Author <\/a><\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">Researchers also studied immune cells from mice fed a high\u2011fat diet and analyzed blood samples from healthy human volunteers to better understand the cellular mechanisms involved in immune dysregulation linked to obesity.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">\u201cThe findings suggest that short\u2011term weight loss may not immediately reduce the risk of some diseases and health issues associated with obesity, including Type 2 diabetes and some cancers,\u201d wrote study author Claudio Mauro, a professor at the University of Birmingham.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">Mauro said reversing what researchers describe as an \u201cobesity memory\u201d in the body\u2019s cells would likely require sustained weight management following major weight loss.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">\u201cThat process may take five to 10 years,\u201d he said.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">Copyright 2026 Nexstar Media, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\"><a data-yga=\"{\" ylinkelement=\"\" href=\"https:\/\/www.newsnationnow.com\" rel=\"nofollow noopener\" target=\"_blank\" data-ylk=\"elm:link;elmt:article_link;slk:For the latest news, weather, sports, and streaming video, head to NewsNation.;itc:0;sec:content-canvas\" class=\"link \"> For the latest news, weather, sports, and streaming video, head to NewsNation. <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"(NewsNation) \u2014 A new study suggests obesity may leave a lasting \u201cmemory\u201d on the immune system, even after&hellip;\n","protected":false},"author":2,"featured_media":622279,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[34],"tags":[96695,97,53454,269702,5451,269701,986,53462,3458],"class_list":["post-622278","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-childhood-obesity","tag-health","tag-immune-cells","tag-immune-dysregulation","tag-immune-system","tag-normal-weight","tag-obesity","tag-university-of-birmingham","tag-weight-loss"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/622278","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/comments?post=622278"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/622278\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media\/622279"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media?parent=622278"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/categories?post=622278"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/tags?post=622278"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}