{"id":636733,"date":"2026-05-11T14:59:13","date_gmt":"2026-05-11T14:59:13","guid":{"rendered":"https:\/\/www.newsbeep.com\/us\/636733\/"},"modified":"2026-05-11T14:59:13","modified_gmt":"2026-05-11T14:59:13","slug":"scientists-destroy-covid-and-flu-viruses-in-the-lab-with-sound-waves-sciencealert","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us\/636733\/","title":{"rendered":"Scientists Destroy COVID And Flu Viruses in The Lab With Sound Waves : ScienceAlert"},"content":{"rendered":"<p>Sound waves already used in medical scans may have a surprising new target:  <a href=\"https:\/\/www.sciencealert.com\/virus\" class=\"lar_link lar_link_outgoing\" data-linkid=\"73053\" data-postid=\"200770\" rel=\"nofollow noopener\" target=\"_self\">viruses<\/a>.<\/p>\n<p>In lab experiments, scientists have demonstrated how ultrasound blasts can break down  <a href=\"https:\/\/www.sciencealert.com\/what-is-influenza\" class=\"lar_link lar_link_outgoing\" data-linkid=\"103478\" data-postid=\"200770\" rel=\"nofollow noopener\" target=\"_self\">influenza<\/a> A (H1N1) and  <a href=\"https:\/\/www.sciencealert.com\/coronavirus\" class=\"lar_link lar_link_outgoing\" data-linkid=\"73041\" data-postid=\"200770\" rel=\"nofollow noopener\" target=\"_self\">SARS-CoV-2<\/a>, which causes  <a href=\"https:\/\/www.sciencealert.com\/coronavirus\" class=\"lar_link lar_link_outgoing\" data-linkid=\"73041\" data-postid=\"200770\" rel=\"nofollow noopener\" target=\"_self\">COVID-19<\/a>.<\/p>\n<p>Microscopic vibrations caused by ultrasound waves are sufficient to rupture the membranes surrounding their <a href=\"https:\/\/www.sciencealert.com\/giant-virus-discovered-in-japanese-pond-may-hint-at-multicellular-lifes-origins\" target=\"_blank\" rel=\"noopener nofollow\">viral particles<\/a>, experiments showed, rendering the viruses inactive.<\/p>\n<p>The research was led by a team from the University of S\u00e3o Paulo in Brazil and could one day be an alternative to antivirals and chemical disinfectants for enveloped viruses, which have an outer membrane that&#8217;s vulnerable to attack.<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/www.newsbeep.com\/us\/wp-content\/uploads\/2026\/05\/1778511549_179_0.jpg\" alt=\"YouTube Thumbnail\" tabindex=\"0\" role=\"button\" class=\"youtube-thumbnail-preview\" loading=\"lazy\"\/> frameborder=&#8221;0\u2033 allow=&#8221;accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share&#8221; referrerpolicy=&#8221;strict-origin-when-cross-origin&#8221; allowfullscreen&gt;<\/p>\n<p>&#8220;It&#8217;s kind of like fighting the  <a href=\"https:\/\/www.sciencealert.com\/virus\" class=\"lar_link lar_link_outgoing\" data-linkid=\"73053\" data-postid=\"200770\" rel=\"nofollow noopener\" target=\"_self\">virus<\/a> with a shout,&#8221; <a href=\"https:\/\/agencia.fapesp.br\/scientists-use-ultrasound-to-destroy-influenza-a-and-covid-19-viruses-without-damaging-human-cells\/57968\" rel=\"nofollow noopener\" target=\"_blank\">says<\/a> computational physicist Odemir Martinez Bruno, from the University of S\u00e3o Paulo.<\/p>\n<p>&#8220;In this study, we proved that the energy of sound waves causes morphological changes in viral particles until they explode, a phenomenon comparable to what happens with popcorn.&#8221;<\/p>\n<p>The lab experiments were performed with ultrasound machines <a href=\"https:\/\/www.nhs.uk\/tests-and-treatments\/ultrasound-scan\/\" rel=\"nofollow noopener\" target=\"_blank\">used in hospitals<\/a>, with the viruses exposed to ultrasound frequencies in the 3\u201320 MHz range.<\/p>\n<p>The researchers took snapshots of physical changes and then tested whether the treated SARS-CoV-2 samples could still infect lab models of host cells (Ver-E6 cells).<\/p>\n<p>There was clear evidence of physical destruction of the viral envelopes, and subsequently, SARS-CoV-2&#8217;s ability to infect model host cells was sharply reduced.<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/www.newsbeep.com\/us\/wp-content\/uploads\/2026\/05\/Experimental-schematic-illustrating-ultrasound-exposure-of-viral-suspensions--642x268.jpg\" alt=\"An illustration showing the experiment\" width=\"642\" height=\"268\" class=\"size-medium wp-image-200845\"   loading=\"lazy\"\/>Researchers exposed viral samples to ultrasound before infecting lab cells with them. (Veras et al., Sci. Rep., 2026)<\/p>\n<p>The approach relies on <a href=\"https:\/\/en.wikipedia.org\/wiki\/Acoustic_resonance\" rel=\"nofollow noopener\" target=\"_blank\">acoustic resonance<\/a>, and both the ultrasound frequency and the shape of the viral particles matter.<\/p>\n<p>The idea is that the frequency of the sound wave matches the natural vibrational frequency of the viral envelope, leading to amplified vibrations that destroy it. Essentially, only the virus responds to the energy of the sound waves, not the host cells.<\/p>\n<p>Under the tested conditions, the viral particles appeared far more vulnerable than the surrounding cells.<\/p>\n<p>Analysis confirmed that the temperature and pH of the surrounding cells remained stable, ruling out thermal or chemical damage as the reason for the breakdown of the viral particles.<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/www.newsbeep.com\/us\/wp-content\/uploads\/2026\/05\/VirusBlast.jpg\" alt=\"Virus chart\" width=\"642\" height=\"433\" class=\"wp-image-200773 size-full\"   loading=\"lazy\"\/>Effects of ultrasound treatment. Top row: Lab cells (with nuclei shown in blue) infected with untreated samples of SARS-CoV-2 (viral spike proteins in green and viral RNA in red). Bottom row: Lab cells infected with samples of SARS-CoV-2 exposed to sound waves. (Veras et al., Sci. Rep., 2026)<\/p>\n<p>The researchers also point out that viral particles like those tested are spherical, the optimal shape for <a href=\"https:\/\/www.sciencealert.com\/scientists-3d-print-material-deep-inside-the-body-using-ultrasound\" rel=\"nofollow noopener\" target=\"_blank\">ultrasound sensitivity<\/a>.<\/p>\n<p>&#8220;The phenomenon is entirely geometric,&#8221; <a href=\"https:\/\/agencia.fapesp.br\/scientists-use-ultrasound-to-destroy-influenza-a-and-covid-19-viruses-without-damaging-human-cells\/57968\" rel=\"nofollow noopener\" target=\"_blank\">says<\/a> Bruno.<\/p>\n<p>&#8220;Spherical particles, such as many enveloped viruses, absorb ultrasound wave energy more effectively. It&#8217;s that accumulation of energy inside the particle that causes changes in the structure of the viral envelope until it ruptures.&#8221;<\/p>\n<p>If these particles were triangular or square, the impacts wouldn&#8217;t be the same.<\/p>\n<p><a href=\"https:\/\/www.sciencealert.com\/newsletter?utm_source=promo_generic_health\" rel=\"nofollow noopener\" target=\"_blank\"><img decoding=\"async\" src=\"https:\/\/www.newsbeep.com\/us\/wp-content\/uploads\/2026\/03\/Generic-Health-Promo-Final-642x273.jpg\" alt=\"Subscribe to ScienceAlert's free fact-checked newsletter\" width=\"642\" height=\"273\" class=\"alignnone wp-image-182810 size-medium\"   loading=\"lazy\"\/><\/a><\/p>\n<p>&#8220;Ultrasound is already used to sterilize dental and surgical equipment, but it works through a different physical phenomenon called cavitation, which destroys biological material,&#8221; Bruno <a href=\"https:\/\/agencia.fapesp.br\/scientists-use-ultrasound-to-destroy-influenza-a-and-covid-19-viruses-without-damaging-human-cells\/57968\" rel=\"nofollow noopener\" target=\"_blank\">explains<\/a>.<\/p>\n<p>&#8220;While cavitation occurs at low frequencies and destroys both viruses and tissues through the collapse of gas bubbles, acoustic resonance operates at high frequencies.&#8221;<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.newsbeep.com\/us\/wp-content\/uploads\/2026\/05\/41598_2026_37584_Fig5_HTML-642x825.webp.webp\" alt=\"Diagram showing two proposed ultrasound mechanisms for disrupting virus particles: cavitation in the kHz range and resonance in the MHz range, with resonance damaging viruses while leaving host cells unchanged.\" width=\"642\" height=\"825\" class=\"size-medium wp-image-200848\"  \/>Illustration of ultrasound-mediated physical mechanisms: (A) cavitation, which operates in the KHz range, is used to sterilize medical equipment; (B) resonance, which operates in the MHz range. (Veras et al., Sci. Rep., 2026)<\/p>\n<p>Acoustic resonance ultrasound could address certain limitations of drug treatments.<\/p>\n<p>The new method didn&#8217;t show the same destructive effects in model host cells or the surrounding solution under lab conditions.<\/p>\n<p>And because the target is a physical structure rather than a single molecular pathway, the researchers hope it could better deal with viruses <a href=\"https:\/\/www.sciencealert.com\/microbes-in-space-mutated-and-developed-a-remarkable-ability\" rel=\"nofollow noopener\" target=\"_blank\">as they mutate<\/a> (which wouldn&#8217;t change the particles&#8217; physical shape).<\/p>\n<p>The team is hopeful their new approach will work across <a href=\"https:\/\/www.sciencealert.com\/investigations-begin-after-suspected-outbreak-of-rare-hantavirus-kills-3-people\" rel=\"nofollow noopener\" target=\"_blank\">other viral infections<\/a>, and they have already begun investigating how dengue, <a href=\"https:\/\/www.sciencealert.com\/the-zika-virus-s-most-heartbreaking-symptom-traced-to-a-recent-mutation\" rel=\"nofollow noopener\" target=\"_blank\">Zika<\/a>, and <a href=\"https:\/\/www.sciencealert.com\/what-is-chikungunya-a-guide-to-the-virus-spreading-in-china\" rel=\"nofollow noopener\" target=\"_blank\">Chikungunya<\/a> could be targeted in the same way.<\/p>\n<p>Ultrasound is generally painless, non-invasive, relatively easy to apply, and can be precisely targeted, so researchers have been exploring several new ways of using it, including for <a href=\"https:\/\/www.sciencealert.com\/ultrasound-can-probe-deep-into-the-brain-to-relieve-pain\" target=\"_blank\" rel=\"noopener nofollow\">pain relief in the brain<\/a> and <a href=\"https:\/\/www.sciencealert.com\/alzheimers-and-cancer-may-soon-be-treated-with-sounds-we-cant-hear\" target=\"_blank\" rel=\"noopener nofollow\">cancer treatment<\/a>.<\/p>\n<p>The finding here is exciting, but it is not yet a treatment. There&#8217;s still a lot of work to do, including further fine-tuning of the ultrasound frequencies.<\/p>\n<p>This study was limited to lab tests rather than any experiments in animals or humans, and only on two different virus types. It&#8217;s a strong starting point, but it&#8217;s still early days for this technology.<\/p>\n<p>Related: <a href=\"https:\/\/www.sciencealert.com\/scientists-develop-new-antibody-for-virus-that-infects-95-of-people\" rel=\"nofollow noopener\" target=\"_blank\">Scientists Develop New Antibody for Virus That Infects 95% of People<\/a><\/p>\n<p>&#8220;Although it&#8217;s still far from clinical use, this is a promising strategy against enveloped viruses in general, since developing chemical antivirals is complex and yields difficult results,&#8221; <a href=\"https:\/\/agencia.fapesp.br\/scientists-use-ultrasound-to-destroy-influenza-a-and-covid-19-viruses-without-damaging-human-cells\/57968\" rel=\"nofollow noopener\" target=\"_blank\">says<\/a> pharmacologist Fl\u00e1vio Prot\u00e1sio Veras, from the University of S\u00e3o Paulo.<\/p>\n<p>&#8220;Furthermore, it&#8217;s a &#8216;green&#8217; solution, as it generates no waste, causes no environmental impact, and doesn&#8217;t promote viral resistance.&#8221;<\/p>\n<p>The research has been published in <a href=\"https:\/\/doi.org\/10.1038\/s41598-026-37584-x\" rel=\"nofollow noopener\" target=\"_blank\">Scientific Reports<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"Sound waves already used in medical scans may have a surprising new target: viruses. In lab experiments, scientists&hellip;\n","protected":false},"author":2,"featured_media":636734,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[34],"tags":[97,1352],"class_list":["post-636733","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-health","tag-msft-content"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/636733","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/comments?post=636733"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/636733\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media\/636734"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media?parent=636733"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/categories?post=636733"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/tags?post=636733"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}