{"id":654874,"date":"2026-05-20T18:14:22","date_gmt":"2026-05-20T18:14:22","guid":{"rendered":"https:\/\/www.newsbeep.com\/us\/654874\/"},"modified":"2026-05-20T18:14:22","modified_gmt":"2026-05-20T18:14:22","slug":"why-ai-cannot-do-good-science-without-humans","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us\/654874\/","title":{"rendered":"Why AI cannot do good science without humans"},"content":{"rendered":"<p>                        <img decoding=\"async\" class=\"figure__image\" alt=\"Four scientists in white lab coats collaborating at a computer in a laboratory.\" loading=\"lazy\" src=\"https:\/\/www.newsbeep.com\/us\/wp-content\/uploads\/2026\/05\/d41586-026-01551-3_52435580.jpg\"\/><\/p>\n<p class=\"figure__caption u-sans-serif\">Training and mentoring the next generation of researchers is an important role for humans.Credit: Getty<\/p>\n<p>Does humanity need science? The Nobel prizewinner <a href=\"https:\/\/www.nature.com\/articles\/415851a\" data-track=\"click\" data-label=\"https:\/\/www.nature.com\/articles\/415851a\" data-track-category=\"body text link\" rel=\"nofollow noopener\" target=\"_blank\">Max Perutz<\/a> posed this question in a landmark essay<a href=\"#ref-CR1\" data-track=\"click\" data-action=\"anchor-link\" data-track-label=\"go to reference\" data-track-category=\"references\">1<\/a> in 1989. His conclusion, unsurprisingly, was \u2018yes\u2019. Had he lived to see the era of artificial intelligence, he might have inverted his framing of the question: does science need humanity?<\/p>\n<p><a href=\"https:\/\/www.nature.com\/articles\/s41586-026-10644-y\" class=\"u-link-inherit\" data-track=\"click\" data-track-label=\"recommended article\" rel=\"nofollow noopener\" target=\"_blank\"><img decoding=\"async\" class=\"recommended__image\" alt=\"\" src=\"https:\/\/www.newsbeep.com\/us\/wp-content\/uploads\/2026\/05\/d41586-026-01551-3_52435846.jpg\"\/><\/p>\n<p class=\"recommended__title u-serif\">Read the paper: Accelerating scientific discovery with Co-Scientist<\/p>\n<p><\/a><\/p>\n<p>Two studies in Nature provide a glimpse of what some are interpreting as humanity\u2019s shrinking role in scientific discovery in Perutz\u2019s own field, molecular biology. Both describe a pivotal step towards truly <a href=\"https:\/\/www.nature.com\/articles\/d41586-025-00602-5\" data-track=\"click\" data-label=\"https:\/\/www.nature.com\/articles\/d41586-025-00602-5\" data-track-category=\"body text link\" rel=\"nofollow noopener\" target=\"_blank\">AI-driven drug discovery<\/a>, in which a system of <a href=\"https:\/\/www.nature.com\/articles\/d41586-026-01257-6\" data-track=\"click\" data-label=\"https:\/\/www.nature.com\/articles\/d41586-026-01257-6\" data-track-category=\"body text link\" rel=\"nofollow noopener\" target=\"_blank\">connected AI agents<\/a> is trained to autonomously navigate multi-step workflows. The system trawled scholarly literature, formed hypotheses, interpreted data and engaged in internal debate to arrive at candidate drugs to treat a particular disease.<\/p>\n<p>The results are impressive, but also highlight something else: AI scientists can and should empower human researchers. They cannot and should not replace them.<\/p>\n<p><a href=\"https:\/\/www.nature.com\/articles\/s41586-026-10644-y\" class=\"u-link-inherit\" data-track=\"click\" data-track-label=\"recommended article\" rel=\"nofollow noopener\" target=\"_blank\"><img decoding=\"async\" class=\"recommended__image\" alt=\"\" src=\"https:\/\/www.newsbeep.com\/us\/wp-content\/uploads\/2026\/05\/d41586-026-01551-3_52435852.jpg\"\/><\/p>\n<p class=\"recommended__title u-serif\">Read the paper: A multi-agent system for automating scientific discovery<\/p>\n<p><\/a><\/p>\n<p>In one study, a team based at FutureHouse, a non-profit AI research laboratory in San Francisco, California, asked its AI system, called Robin, to find a treatment for the eye disorder dry age-related macular degeneration<a href=\"#ref-CR2\" data-track=\"click\" data-action=\"anchor-link\" data-track-label=\"go to reference\" data-track-category=\"references\">2<\/a>. Robin\u2019s agents searched the scientific literature to derive a therapeutic strategy, identified candidate molecules and selected assays to test them. The experiments Robin suggested were then handed over to humans, who conducted the studies and fed the results back to Robin for analysis, interpretation and the design of follow-up studies. The team estimates that Robin reduced the time needed for the project 200-fold compared with a typical human workflow.<\/p>\n<p>A second group led by researchers at Google, based in Mountain View, California, used its AI-agent system, called Co-Scientist, to look for approved drugs that could be repurposed to treat a form of leukaemia, and to discover drug targets to treat liver fibrosis<a href=\"#ref-CR3\" data-track=\"click\" data-action=\"anchor-link\" data-track-label=\"go to reference\" data-track-category=\"references\">3<\/a>. Humans provided input throughout the process, helping to prioritize hypotheses and approaches. The team also asked the agents to develop a hypothesis to explain why many species of bacterium share a particular suite of antibiotic-resistance genes. Scientists, including some of the project\u2019s authors, had been investigating this microbial puzzle for around a decade, but had not yet published the results. Co-Scientist arrived at the same hypothesis as the researchers \u2014 within days.<\/p>\n<p><a href=\"https:\/\/www.nature.com\/articles\/d41586-026-01596-4\" class=\"u-link-inherit\" data-track=\"click\" data-track-label=\"recommended article\" rel=\"nofollow noopener\" target=\"_blank\"><img decoding=\"async\" class=\"recommended__image\" alt=\"\" src=\"https:\/\/www.newsbeep.com\/us\/wp-content\/uploads\/2026\/05\/d41586-026-01551-3_52436126.jpg\"\/><\/p>\n<p class=\"recommended__title u-serif\">Teams of AI agents boost speed of research<\/p>\n<p><\/a><\/p>\n<p>These projects represent a significant step forwards. But for all the \u2018wow\u2019 factor, it is crucial to bear in mind that the AI systems were not working alone. In both cases, humans framed the initial project, performed experiments, offered guidance and checked the agents\u2019 output along the way. That is a feature, not a bug \u2014 and shutting humans out of the loop would not be easy.<\/p>\n<p>For one thing, the creation of a fully autonomous AI researcher would require many more AI agents to be cross-linked, and scientists would need to ensure that those agents could maintain focus and coordinate efficiently with one another during long, complex tasks<a href=\"#ref-CR4\" data-track=\"click\" data-action=\"anchor-link\" data-track-label=\"go to reference\" data-track-category=\"references\">4<\/a>,<a href=\"#ref-CR5\" data-track=\"click\" data-action=\"anchor-link\" data-track-label=\"go to reference\" data-track-category=\"references\">5<\/a>. It is also not yet clear whether AI agents would be able to master every step of the process of drug development. Even if they could, <a href=\"https:\/\/www.nature.com\/articles\/d41586-026-00934-w\" data-track=\"click\" data-label=\"https:\/\/www.nature.com\/articles\/d41586-026-00934-w\" data-track-category=\"body text link\" rel=\"nofollow noopener\" target=\"_blank\">human oversight would still be needed<\/a> to catch hallucinations (AI data fabrication) and misinterpretations, and to ensure that certain tasks are done correctly \u2014 for example, that the data AI harvests from databases for its analyses are used appropriately.<\/p>\n<p><a href=\"https:\/\/www.nature.com\/articles\/d41586-026-01257-6\" class=\"u-link-inherit\" data-track=\"click\" data-track-label=\"recommended article\" rel=\"nofollow noopener\" target=\"_blank\"><img decoding=\"async\" class=\"recommended__image\" alt=\"\" src=\"https:\/\/www.newsbeep.com\/us\/wp-content\/uploads\/2026\/05\/d41586-026-01551-3_52435794.jpg\"\/><\/p>\n<p class=\"recommended__title u-serif\">AI doom warnings are getting louder. Are they realistic?<\/p>\n<p><\/a><\/p>\n<p>More broadly, the expertise of researchers, and the accumulated wisdom of teams that have worked on a problem, perhaps for decades, might prove impossible for machines to replicate. Humans are also needed to train future generations, and their knowledge is built, in part, on lessons learnt from failures and inefficient meanderings. Human messiness, curiosity and playfulness have fuelled countless discoveries, and helped to inform society\u2019s ethical frameworks. AI systems might offer greater efficiency in some instances, but we don\u2019t yet know whether greater efficiency equates to greater insight.<\/p>\n<p>These caveats should be borne in mind as society argues over competing visions of how AI should fit into the future. Some researchers see in AI tools a path to accelerated discovery, <a href=\"https:\/\/www.nature.com\/articles\/d41586-026-01477-w\" data-track=\"click\" data-label=\"https:\/\/www.nature.com\/articles\/d41586-026-01477-w\" data-track-category=\"body text link\" rel=\"nofollow noopener\" target=\"_blank\">relief from the tedium<\/a> that comes with much day-to-day lab work and a <a href=\"https:\/\/www.nature.com\/articles\/d41586-026-00365-7\" data-track=\"click\" data-label=\"https:\/\/www.nature.com\/articles\/d41586-026-00365-7\" data-track-category=\"body text link\" rel=\"nofollow noopener\" target=\"_blank\">faster, cheaper way to create medicines<\/a> and make other discoveries. Others see a future in which scientific literature is polluted with slop, human scientists cannot find suitable training or work, and research is untempered by human empathy, ethics and wisdom.<\/p>\n<p><a href=\"https:\/\/www.nature.com\/articles\/d41586-026-00934-w\" class=\"u-link-inherit\" data-track=\"click\" data-track-label=\"recommended article\" rel=\"nofollow noopener\" target=\"_blank\"><img decoding=\"async\" class=\"recommended__image\" alt=\"\" src=\"https:\/\/www.newsbeep.com\/us\/wp-content\/uploads\/2026\/05\/d41586-026-01551-3_52435798.jpg\"\/><\/p>\n<p class=\"recommended__title u-serif\">AI scientists are changing research \u2014 institutions, funders and publishers must respond<\/p>\n<p><\/a><\/p>\n<p>Scientists should not allow a negative view of AI to drive them away from exploring the possibilities that AI co- scientists might hold for research. Equally, however, they must rise above the din of AI hype and advocate for their own importance \u2014 to remind the wider public, funders and fellow researchers that science still needs humanity, and that not every grant proposal need include an AI project.<\/p>\n<p>Perutz began his essay with a false dialectic that also plagues many modern discussions of AI: \u201cIs scientific research the noblest pursuit of the human mind, from which springs a never-ceasing stream of beneficial discoveries, or is it a sorcerer\u2019s broom that threatens us all with destruction?\u201d. These opposing extremes, both true in their own way, should not be allowed to distort AI\u2019s true potential \u2014 or obscure its limitations.<\/p>\n","protected":false},"excerpt":{"rendered":"Training and mentoring the next generation of researchers is an important role for humans.Credit: Getty Does humanity need&hellip;\n","protected":false},"author":2,"featured_media":654875,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[32],"tags":[19944,1159,1877,1160,92217,79,7139],"class_list":["post-654874","post","type-post","status-publish","format-standard","has-post-thumbnail","category-science","tag-computer-science","tag-humanities-and-social-sciences","tag-machine-learning","tag-multidisciplinary","tag-research-data","tag-science","tag-scientific-community"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/654874","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/comments?post=654874"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/654874\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media\/654875"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media?parent=654874"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/categories?post=654874"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/tags?post=654874"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}