{"id":678802,"date":"2026-06-02T00:18:14","date_gmt":"2026-06-02T00:18:14","guid":{"rendered":"https:\/\/www.newsbeep.com\/us\/678802\/"},"modified":"2026-06-02T00:18:14","modified_gmt":"2026-06-02T00:18:14","slug":"its-time-to-think-outside-the-box-nc-street-drug-scientist-warns-about-deadly-substance-wral-com","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us\/678802\/","title":{"rendered":"&#8216;It&#8217;s time to think outside the box&#8217;: NC street drug scientist warns about deadly substance :: WRAL.com"},"content":{"rendered":"<p>A substance, crowding emergency rooms in some states, is appearing in North Carolina\u2019s street drug supply, according to scientists at the University of North Carolina\u2019s Street Drug Analysis Lab.<\/p>\n<p>The substance, called medetomidine, has become a growing concern for public health officials and addiction experts who warn that its withdrawal symptoms can be life-threatening. <\/p>\n<p>Street drug scientists say medetomidine has already overwhelmed emergency rooms in cities like Chicago, Philadelphia and Pittsburgh, and while North Carolina has not reached that point, they are watching it closely. <\/p>\n<p>\t\t\t\t\t\t\tA survivor&#8217;s warning: Woman says she nearly lost her hand to drug addiction\u00a0<\/p>\n<p>The issue is deeply personal for people like Alexis West, whose struggles with addiction left lasting physical reminders.<\/p>\n<p>\u201cI&#8217;ve gone through a lot in my life,\u201d West said. There are good parts, of course, but it&#8217;s just been a lot of bad. And I used the drugs to numb everything.\u201d<\/p>\n<p>West said nearly losing her hand became the turning point that pushed her toward recovery through Edgecombe County\u2019s Emergency Paramedic Program. The experience also introduced her to street drug testing programs that revealed what was actually in the substances she was using.<\/p>\n<p>\u201cYou think you&#8217;re doing one thing, and really, you&#8217;re doing another,\u201d West said.<\/p>\n<p>Edgecombe County sends drug samples to UNC\u2019s Street Drug Analysis Lab, where scientists test substances circulating in local communities and return the results to health officials and outreach programs.<\/p>\n<p>West said the fentanyl she believed she was taking was often mixed with several other substances.<\/p>\n<p>\u201cHalf of the names you can&#8217;t even pronounce. It&#8217;s not good that you&#8217;re putting drugs in your body. But then again, it&#8217;s scary, because it&#8217;s like these things; you don&#8217;t even know what they are,\u201d she said.<\/p>\n<p>\t\t\t\t\t\t\tWhat is medetomidine?<\/p>\n<p>Among the substances identified by the lab is medetomidine, which scientists say first appeared in North Carolina\u2019s drug supply in 2022. One sample collected in Tarboro in April showed the substance mixed with multiple drugs in what researchers described as a \u201cmessy brew.\u201d<\/p>\n<p>\u00a0The\u00a0<a href=\"https:\/\/www.cdc.gov\/han\/php\/notices\/han00527.html\" rel=\"nofollow noopener\" target=\"_blank\">U.S. Centers for Disease Control and Prevention [CDC] states<\/a>\u00a0that medetomidine is\u00a0an alpha-2 adrenergic agonist sedative, more potent and longer-acting than clonidine and xylazine. It was first identified in the illegal drug supply in 2021, according to the CDC.\u00a0\u00a0<\/p>\n<p>According to the CDC,\u00a0medetomidine\u00a0is not approved for human use but is approved for sedation and analgesia in dogs. It is also known as &#8220;rhino tranq,&#8221; &#8220;mede&#8221; or &#8220;dex.&#8221;<\/p>\n<p>\u201cIt\u2019s a fraternal twin to a molecule called xylazine that we\u2019ve had in North Carolina for a few years, just a few different atoms,\u201d said UNC Street Drug Scientist Nabarun Dasgupta.<\/p>\n<p>Dasgupta said those small molecular differences can have severe consequences, especially for people who suddenly stop using the drug.<\/p>\n<p>\u201cIf someone stops cold turkey, there&#8217;s a very good chance that they&#8217;ll have a heart attack and end up in the ICU for a week,\u201d he said.<\/p>\n<p>The CDC states that medetomidine can cause profound sedation, bradycardia and hypotension. Stopping medetomidine following regular use may lead to severe withdrawal, similar to clonidine withdrawal, with symptoms including hypertension, anxiety, nausea, vomiting and fluctuating alertness, that can require emergency or intensive care.<\/p>\n<p>Because fentanyl is involved in most overdoses involving medetomidine, the CDC states opioid overdose reversal medications should be administered to restore normal breathing in suspected overdoses.<\/p>\n<p>Watch:\u00a0<a href=\"https:\/\/youtu.be\/Gj0wF8Dui8o?si=phPq8uAtNYx-NEO4\" rel=\"nofollow noopener\" target=\"_blank\">UNC lab tracks America&#8217;s &#8216;synthetic soup&#8217; of street drugs with Dr. Nabarun Dasgupta<\/a><\/p>\n<p>\t\t\t\t\t\t\tStopping the spread of\u00a0medetomidine <\/p>\n<p>Dasgupta\u00a0said education and drug-testing tools could help slow the spread of medetomidine before it becomes more widespread in North Carolina.<\/p>\n<p>\u201cI think it&#8217;s time to think outside the box,\u201d Dasgupta said. \u201cThere are test strips that can detect whether the drugs have medetomidine in it, and they&#8217;re cheap, couple bucks, and so we are encouraging people to be educated about this, to use those test strips, and if they are starting to see their supply regularly contaminated medetomidine, to really think about &#8230; &#8216;it might be the time to really stop using drugs in the way I have been.&#8217;\u201d<\/p>\n<p>As medetomidine continues appearing in drug samples across the state, researchers and recovery advocates say awareness may be critical in preventing a larger public health crisis.<\/p>\n","protected":false},"excerpt":{"rendered":"A substance, crowding emergency rooms in some states, is appearing in North Carolina\u2019s street drug supply, according to&hellip;\n","protected":false},"author":2,"featured_media":678803,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[34],"tags":[9038,2605,11983,97,3043,6928,155410,134299],"class_list":["post-678802","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-addiction","tag-drugs","tag-fentanyl","tag-health","tag-opioids","tag-unc","tag-wral-investigates","tag-wral-specialists"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/678802","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/comments?post=678802"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/678802\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media\/678803"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media?parent=678802"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/categories?post=678802"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/tags?post=678802"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}