{"id":712749,"date":"2026-06-19T03:03:08","date_gmt":"2026-06-19T03:03:08","guid":{"rendered":"https:\/\/www.newsbeep.com\/us\/712749\/"},"modified":"2026-06-19T03:03:08","modified_gmt":"2026-06-19T03:03:08","slug":"joint-pain-supplement-tied-to-faster-alzheimers-progression","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us\/712749\/","title":{"rendered":"Joint-Pain Supplement Tied to Faster Alzheimer&#8217;s Progression"},"content":{"rendered":"<p class=\"storyParagraph\">&#13;<br \/>\n                                        A supplement that many older Americans swallow for their knees may not be so benign for their brains. University of Florida researchers report that glucosamine use was linked to a greater shift from mild cognitive impairment to Alzheimer&#8217;s disease in a large review of patient records, reports the <a href=\"https:\/\/theconversation.com\/glucosamine-supplements-may-speed-memory-loss-from-alzheimers-new-research-shows-282467\" rel=\"nofollow noopener\" target=\"_blank\">Conversation<\/a>. Using AI to sift through UF Health data from 2012 to 2024, the team found about 8% of patients with either Alzheimer&#8217;s or mild cognitive impairment reported taking glucosamine, per a <a href=\"https:\/\/www.eurekalert.org\/news-releases\/1131192\" rel=\"nofollow noopener\" target=\"_blank\">release<\/a>. After adjusting for age, sex, and demographics, it was found that using glucosamine was tied to a 25% greater risk of mild cognitive impairment advancing to dementia.&#13;\n                                    <\/p>\n<p class=\"storyParagraph\">&#13;<br \/>\n                                        Among those already diagnosed with Alzheimer&#8217;s or related dementias, glucosamine use was also tied to a 25% higher risk of death over time. The study, published in <a href=\"https:\/\/www.nature.com\/articles\/s42255-026-01538-4\" rel=\"nofollow noopener\" target=\"_blank\">Nature Metabolism<\/a>, doesn&#8217;t prove that glucosamine, which many take for joint pain and arthritis, causes the decline, but it&#8217;s backed by mouse experiments and brain-tissue analyses suggesting the supplement feeds into an overactive &#8220;sugar-tagging&#8221; process on proteins seen in Alzheimer&#8217;s. That metabolic pathway, the authors say, could be a new treatment target\u2014but they stress that the findings need confirmation in clinical trials before changing medical guidance.&#13;\n                                    <\/p>\n","protected":false},"excerpt":{"rendered":"&#13; A supplement that many older Americans swallow for their knees may not be so benign for their&hellip;\n","protected":false},"author":2,"featured_media":712750,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[34],"tags":[42938,97],"class_list":["post-712749","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-alzheimer","tag-health"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/712749","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/comments?post=712749"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/712749\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media\/712750"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media?parent=712749"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/categories?post=712749"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/tags?post=712749"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}