{"id":728259,"date":"2026-06-27T01:06:28","date_gmt":"2026-06-27T01:06:28","guid":{"rendered":"https:\/\/www.newsbeep.com\/us\/728259\/"},"modified":"2026-06-27T01:06:28","modified_gmt":"2026-06-27T01:06:28","slug":"low-testosterone-is-linked-to-a-higher-risk-of-cancer-study-finds-sciencealert","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us\/728259\/","title":{"rendered":"Low Testosterone Is Linked to a Higher Risk of Cancer, Study Finds : ScienceAlert"},"content":{"rendered":"<p>We may not have a definitive cure for  <a href=\"https:\/\/www.sciencealert.com\/cancer\" class=\"lar_link lar_link_outgoing\" data-linkid=\"73077\" data-postid=\"206564\" rel=\"nofollow noopener\" target=\"_self\">cancer<\/a> yet, but thanks to research, we have an expanding list of risk factors, including <a href=\"https:\/\/www.sciencealert.com\/walking-daily-linked-to-lower-risk-of-13-cancers-major-study-finds\" rel=\"nofollow noopener\" target=\"_blank\">levels of exercise<\/a>, <a href=\"https:\/\/www.sciencealert.com\/one-drink-of-alcohol-a-day-raises-your-risk-of-10-cancers-study-warns\" rel=\"nofollow noopener\" target=\"_blank\">alcohol intake<\/a>, <a href=\"https:\/\/www.sciencealert.com\/your-weight-at-different-ages-could-affect-your-risk-of-multiple-cancers\" rel=\"nofollow noopener\" target=\"_blank\">weight<\/a>, and even <a href=\"https:\/\/www.sciencealert.com\/marriage-linked-to-lower-cancer-risk-in-study-of-4-million-cases\" rel=\"nofollow noopener\" target=\"_blank\">marriage status<\/a>.<\/p>\n<p>Now, a large new analysis suggests something else may carry a warning signal.<\/p>\n<p>An international team examined 11 long-running studies involving more than 26,000 men of varying ages, with follow-up periods of at least five years.<\/p>\n<p>The data showed that very low <a href=\"https:\/\/www.sciencealert.com\/expert-reveals-what-can-happen-if-testosterone-gel-rubs-onto-others\" rel=\"nofollow noopener\" target=\"_blank\">testosterone levels<\/a> were associated with a significantly higher risk of dying from cancer, although one type of cancer was an exception.<\/p>\n<p>The finding does not mean low testosterone causes cancer, and the researchers emphasize it is not a reason for men to start taking testosterone supplements.<\/p>\n<p>It suggests that low testosterone could be an important marker of future health.<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/www.newsbeep.com\/us\/wp-content\/uploads\/2026\/06\/CancerChart-1.jpg\" alt=\"Cancer chart\" width=\"642\" height=\"437\" class=\"wp-image-206567 size-full\"   loading=\"lazy\"\/>Risk of cancer death by testosterone level (lower testosterone on the left). (Marriott et al, Lancet Healthy Longev., 2026)<\/p>\n<p>Testosterone levels have <a href=\"https:\/\/doi.org\/10.7326\/M23-2781\" rel=\"nofollow noopener\" target=\"_blank\">been linked to<\/a> poor health before, but the relationship of the primary male sex hormone to cancer risk hasn&#8217;t been clear up to this point.<\/p>\n<p>Given the hormone&#8217;s close connections to cell growth, the researchers behind the study wanted to investigate further.<\/p>\n<p>&#8220;We wanted to know whether the concentration of these hormones in the blood was related to the risk of men being diagnosed with, or dying from, cancer in the future,&#8221; <a href=\"https:\/\/www.uwa.edu.au\/news\/article\/2026\/june\/low-testosterone-linked-to-cancer-risk-in-men\" rel=\"nofollow noopener\" target=\"_blank\">says<\/a> endocrinologist Bu Yeap, from The University of Western Australia.<\/p>\n<p>For the purposes of the study, testosterone concentrations were measured in nanomoles per liter or nmol\/L, a standard measure. Young, healthy men usually have levels between 10 and 30 nmol\/L.<\/p>\n<p>&#8220;What we saw was that if a man had low testosterone levels \u2013 in the lowest one-fifth compared to the highest one-fifth of the range \u2013 their subsequent risk of dying from cancer was higher, even after allowing for age and other health-related factors,&#8221; <a href=\"https:\/\/www.uwa.edu.au\/news\/article\/2026\/june\/low-testosterone-linked-to-cancer-risk-in-men\" rel=\"nofollow noopener\" target=\"_blank\">says<\/a> Yeap.<\/p>\n<p>Another finding worth noting: Men with very low testosterone levels were at a higher risk of being <a href=\"https:\/\/www.sciencealert.com\/early-signs-of-cancer-found-in-patient-blood-3-years-before-diagnosis\" rel=\"nofollow noopener\" target=\"_blank\">diagnosed with cancer<\/a>, as well as dying from it.<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/www.newsbeep.com\/us\/wp-content\/uploads\/2026\/06\/HazardChart.jpg\" alt=\"Hazard chart\" width=\"642\" height=\"485\" class=\"wp-image-206569 size-full\"   loading=\"lazy\"\/>The researchers collated results from multiple studies: this forest plot shows the cancer death risk between low testosterone and high testosterone. (Marriott et al, Lancet Healthy Longev., 2026)<\/p>\n<p><a href=\"https:\/\/www.sciencealert.com\/cancer-death-rates-fall-to-record-low-in-the-uk-but-some-types-are-rising\" rel=\"nofollow noopener\" target=\"_blank\">Deaths from cancer<\/a> began to increase when testosterone levels fell below 8.6 nmol\/L. For cancer diagnosis, the risk increased with levels below 7.3 nmol\/L.<\/p>\n<p>&#8220;We saw that when baseline testosterone was below 8.6 nmol\/L, subsequent cancer risk started increasing,&#8221; <a href=\"https:\/\/www.uwa.edu.au\/news\/article\/2026\/june\/low-testosterone-linked-to-cancer-risk-in-men\" rel=\"nofollow noopener\" target=\"_blank\">says<\/a> Yeap.<\/p>\n<p>&#8220;This suggests low testosterone is an important biomarker, so it&#8217;s possible that looking at testosterone levels could help us identify men who might do poorly if they get cancer down the track.&#8221;<\/p>\n<p>There was one notable exception: prostate cancer.<\/p>\n<p>That is somewhat surprising, because the prostate is highly responsive to testosterone signals. Further study will be needed to tease out the reason for it.<\/p>\n<p>&#8220;Since reducing testosterone levels is a treatment for prostate cancer, there&#8217;s always been a question of whether the amount of testosterone your own body makes relates to your risk of prostate cancer,&#8221; <a href=\"https:\/\/www.uwa.edu.au\/news\/article\/2026\/june\/low-testosterone-linked-to-cancer-risk-in-men\" rel=\"nofollow noopener\" target=\"_blank\">says<\/a> Yeap.<\/p>\n<p>&#8220;But based on our findings, there&#8217;s no evidence they are related.&#8221;<\/p>\n<p>The data did show that lower levels of <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/2080856\/\" rel=\"nofollow noopener\" target=\"_blank\">sex hormone-binding globulin<\/a> (SHBG) and <a href=\"https:\/\/my.clevelandclinic.org\/health\/body\/22255-luteinizing-hormone\" rel=\"nofollow noopener\" target=\"_blank\">luteinizing hormone<\/a> were associated with an increased likelihood of being diagnosed with <a href=\"https:\/\/www.sciencealert.com\/scientists-predict-prostate-cancer-cases-to-double-within-20-years\" rel=\"nofollow noopener\" target=\"_blank\">prostate cancer<\/a>.<\/p>\n<p><a href=\"https:\/\/www.sciencealert.com\/newsletter?utm_source=promo_stargazing\" rel=\"nofollow noopener\" target=\"_blank\"><img decoding=\"async\" src=\"https:\/\/www.newsbeep.com\/us\/wp-content\/uploads\/2026\/05\/FOMO-1200x628-_Dont-miss-the-next-breakthrough_-cosmic-colourful-642x336.jpg\" alt=\"Subscribe to ScienceAlert's free fact-checked newsletter\" width=\"642\" height=\"336\" class=\"alignnone wp-image-201722 size-medium\"   loading=\"lazy\"\/><\/a><\/p>\n<p>It&#8217;s important to bear in mind that this study doesn&#8217;t show cause and effect \u2013 and again, the researchers are keen to dissuade men from taking extra testosterone supplements to try and reduce their cancer risk.<\/p>\n<p>&#8220;What we would say to men is if they are found for whatever reason to be low in testosterone, it&#8217;s important to go to the doctor for a full check-up,&#8221; <a href=\"https:\/\/www.uwa.edu.au\/news\/article\/2026\/june\/low-testosterone-linked-to-cancer-risk-in-men\" rel=\"nofollow noopener\" target=\"_blank\">explains<\/a> Yeap.<\/p>\n<p>&#8220;It may not show any sign of testicular disease, but it might show other health issues or risk factors they need to address.&#8221;<\/p>\n<p>In other words, levels of key hormones could warn of <a href=\"https:\/\/www.sciencealert.com\/surprising-study-finds-men-with-low-testosterone-more-likely-to-die-early\" rel=\"nofollow noopener\" target=\"_blank\">future health problems<\/a>, including cancer risk, which may be influenced by other factors in the body.<\/p>\n<p>Related: <a href=\"https:\/\/www.sciencealert.com\/new-immune-system-discovery-could-help-beat-a-sneaky-cancer-cell-trick\" rel=\"nofollow noopener\" target=\"_blank\">New Immune System Discovery Could Help Beat a Sneaky Cancer Cell Trick<\/a><\/p>\n<p>&#8220;It could be a wake-up call and encouragement for men to engage in more healthy lifestyle behaviors, and to get regular, holistic checkups to stay on top of their health,&#8221; <a href=\"https:\/\/www.uwa.edu.au\/news\/article\/2026\/june\/low-testosterone-linked-to-cancer-risk-in-men\" rel=\"nofollow noopener\" target=\"_blank\">says<\/a> Yeap.<\/p>\n<p>The research has been published in <a href=\"https:\/\/doi.org\/10.1016\/j.lanhl.2026.100857\" rel=\"nofollow noopener\" target=\"_blank\">The Lancet Healthy Longevity<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"We may not have a definitive cure for cancer yet, but thanks to research, we have an expanding&hellip;\n","protected":false},"author":2,"featured_media":728260,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[34],"tags":[97,1352],"class_list":["post-728259","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-health","tag-msft-content"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/728259","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/comments?post=728259"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/728259\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media\/728260"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media?parent=728259"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/categories?post=728259"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/tags?post=728259"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}