{"id":76994,"date":"2025-08-12T10:58:07","date_gmt":"2025-08-12T10:58:07","guid":{"rendered":"https:\/\/www.newsbeep.com\/us\/76994\/"},"modified":"2025-08-12T10:58:07","modified_gmt":"2025-08-12T10:58:07","slug":"controversial-supplement-may-not-be-so-bad-after-all-but-only-in-these-cases","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us\/76994\/","title":{"rendered":"Controversial supplement may not be so bad after all \u2014 but only in these cases"},"content":{"rendered":"<p>A OK?<\/p>\n<p>Beta-carotene is\u00a0a red-orange pigment <a href=\"https:\/\/nypost.com\/2025\/05\/21\/lifestyle\/viral-carrotmaxxing-trend-sparks-er-visits\/\" rel=\"nofollow noopener\" target=\"_blank\">found in many fruits and vegetables<\/a>. The body converts it into <a href=\"https:\/\/nypost.com\/2025\/03\/06\/health\/rfk-jr-spotlights-vitamin-to-fight-measles-but-experts-say-not-so-fast\/\" rel=\"nofollow noopener\" target=\"_blank\">vitamin A<\/a>, which is vital for good vision, a strong immune system, glowing skin and cellular processes like reproduction and growth.<\/p>\n<p>Most healthy individuals get enough vitamin A from their diet, but those with certain medical conditions may benefit from beta-carotene supplementation to prevent <a href=\"https:\/\/nypost.com\/2025\/03\/12\/health\/should-you-be-taking-a-vitamin-a-supplement\/\" rel=\"nofollow noopener\" target=\"_blank\">vitamin A deficiency<\/a>.<\/p>\n<p>Carrots, sweet potatoes, other orange and yellow produce and dark leafy greens like spinach contain beta-carotene, a form of vitamin A known as provitamin A. larisikstefania \u2013 stock.adobe.com<\/p>\n<p>The problem is that large doses of beta-carotene supplements <a href=\"https:\/\/nypost.com\/2025\/01\/03\/health\/cancer-dietitian-reveals-3-things-she-wont-do-because-of-risks\/\" rel=\"nofollow noopener\" target=\"_blank\">can be harmful<\/a>, especially for smokers and people exposed to asbestos, because <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC9003277\/\" target=\"_blank\" rel=\"noopener nofollow\">studies have shown<\/a> they can <a href=\"https:\/\/nypost.com\/2022\/04\/25\/the-4-common-supplements-that-could-increase-your-risk-of-cancer\" rel=\"nofollow noopener\" target=\"_blank\">increase the risk of lung cancer<\/a>.<\/p>\n<p>In a twist, <a href=\"https:\/\/medschool.ucsd.edu\/about\/news\/archive\/2025\/08-04-cuomo-paradox.html\" target=\"_blank\" rel=\"noopener nofollow\">new research out of UC San Diego<\/a> suggests that excess beta-carotene supplementation may not hurt people who are seriously ill with cancer or heart disease.<\/p>\n<p>The phenomenon is called \u201cCuomo\u2019s Paradox\u201d for biomedical scientist <a href=\"https:\/\/clre.ucsd.edu\/faculty\/raphael-cuomo\/\" target=\"_blank\" rel=\"noopener nofollow\">Raphael Cuomo<\/a>, a professor at UCSD\u2019s School of Medicine.<\/p>\n<p>His theory proposes that things that experts have warned are detrimental \u2014 like obesity, elevated cholesterol and certain antioxidant supplements \u2014 can actually be harmless or even helpful for cancer or <a href=\"https:\/\/nypost.com\/2024\/06\/04\/health\/61-of-us-adults-will-have-cardiovascular-disease-by-2050-report\/\" rel=\"nofollow noopener\" target=\"_blank\">cardiovascular disease patients<\/a>.<\/p>\n<p>People with certain health conditions may benefit from beta-carotene supplementation to prevent vitamin A deficiency. The problem is that large doses of beta-carotene supplements can increase the risk of lung cancer. utah51 \u2013 stock.adobe.com<\/p>\n<p>\u201cUnder Cuomo\u2019s Paradox, a nutrient that seems protective before disease can fail to help (or even hurt) once serious illness enters the picture,\u201d Cuomo told The Post.<\/p>\n<p>\u201cA textbook example of Cuomo\u2019s Paradox,\u00a0beta-carotene\u00a0can be risky in high doses for healthy populations, while studies in sick populations have not linked it to shorter survival.\u201d<\/p>\n<p>Essentially, the dietary or lifestyle choices that help you avoid disease might not be the best approach once serious disease strikes and vice versa.<\/p>\n<p>Cuomo pointed out that several million people have advanced cancer or heart disease.<\/p>\n<p>He recommends that clinicians individualize recommendations for patients rather than copy standard prevention rules.\u00a0<\/p>\n<p>His findings were published this month in the <a href=\"https:\/\/jn.nutrition.org\/article\/S0022-3166(25)00472-9\/fulltext\" target=\"_blank\" rel=\"noopener nofollow\">Journal of Nutrition<\/a>.<\/p>\n<p>As research continues, you should consult with your doctor before taking beta-carotene supplements. <\/p>\n<p>The newly presented \u201cCuomo\u2019s Paradox,\u201d named for biomedical scientist Raphael Cuomo, suggests that excess beta-carotene supplementation may not hurt people who are seriously ill with cancer or heart disease.<\/p>\n<p>Experts generally recommend consuming beta-carotene from food sources.<\/p>\n<p>Carrots, sweet potatoes, other orange and yellow produce and dark leafy greens like spinach contain beta-carotene, a form of vitamin A known as provitamin A.<\/p>\n<p>The other form of vitamin A \u2014 preformed vitamin A or retinol \u2014 is primarily found in animal-based foods such as liver, fish, dairy products and eggs.<\/p>\n<p>Beta-carotene supplementation may be helpful for people with celiac disease, cystic fibrosis, sun sensitivity, vision conditions, malnutrition or trouble absorbing vitamin A.<\/p>\n<p>Symptoms of deficiency include night blindness, reproductive issues, dry, scaly skin and chest infections.<\/p>\n<p>About 75% of Americans take a dietary supplement, <a href=\"https:\/\/www.fda.gov\/drugs\/news-events-human-drugs\/fdas-regulation-dietary-supplements-dr-cara-welch\" target=\"_blank\" rel=\"noopener nofollow\">according to government data<\/a>. Vitamin A, in its various forms, is a common ingredient in supplements.<\/p>\n<p>Consult with your doctor before taking any supplements, especially beta-carotene supplements. Cultura Creative \u2013 stock.adobe.com<\/p>\n<p>After researchers observed that vitamin A possesses anti-cancer properties, there was a lot of optimism that beta-carotene supplements would be a magic bullet in preventing cancer.<\/p>\n<p>But those hopes were dashed in the 1990s, when <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6636175\/\" target=\"_blank\" rel=\"noopener nofollow\">studies suggested<\/a> that not only did beta-carotene supplements not have a protective effect, but they actually increased the risk of lung cancer in smokers.<\/p>\n<p>Beta-carotene is an antioxidant. Under certain circumstances, like high oxygen tension in the lungs of smokers, beta-carotene can increase oxidative stress rather than reduce it.<\/p>\n<p>Now, the US Preventive Services Task Force (USPSTF) <a href=\"https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/2793446\" target=\"_blank\" rel=\"noopener nofollow\">recommends against<\/a> taking beta-carotene supplements for the prevention of cardiovascular disease or cancer.<\/p>\n","protected":false},"excerpt":{"rendered":"A OK? Beta-carotene is\u00a0a red-orange pigment found in many fruits and vegetables. The body converts it into vitamin&hellip;\n","protected":false},"author":2,"featured_media":76995,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[61],"tags":[40302,687,186,8757,8111,97,1492,39942,269,1728,5195,8116,3284,582,27093,2668,673],"class_list":{"0":"post-76994","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-nutrition","8":"tag-antioxidants","9":"tag-cancer","10":"tag-exclusive","11":"tag-eyes","12":"tag-fruit","13":"tag-health","14":"tag-heart-disease","15":"tag-lung-cancer","16":"tag-nutrition","17":"tag-research","18":"tag-skin","19":"tag-smoking","20":"tag-study-says","21":"tag-supplements","22":"tag-vegetables","23":"tag-vitamins","24":"tag-wellness"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/76994","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/comments?post=76994"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/76994\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media\/76995"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media?parent=76994"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/categories?post=76994"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/tags?post=76994"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}