{"id":810427,"date":"2026-08-11T20:36:08","date_gmt":"2026-08-11T20:36:08","guid":{"rendered":"https:\/\/www.newsbeep.com\/us\/810427\/"},"modified":"2026-08-11T20:36:08","modified_gmt":"2026-08-11T20:36:08","slug":"1500-reports-to-hpra-on-anti-obesity-drug-side-effects","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us\/810427\/","title":{"rendered":"1,500 reports to HPRA on anti-obesity drug side effects"},"content":{"rendered":"<p>There have been over 1,500 reports of suspected adverse reactions from weight loss medication, the Health Products Regulatory Authority (HPRA) has confirmed to RT\u00c9 News.<\/p>\n<p>The side effects include gastrointestinal issues, nausea, vomiting and diarrhoea, according to the HPRA.<\/p>\n<p>The HPRA has also received nine reports describing individuals who were known to be taking anti-obesity injections semaglutide, liraglutide or tirzepatide and died alongside the 1,532 side effects.<\/p>\n<p>However, the HPRA said that this did not mean that the medicines caused the side effects or fatalities.<\/p>\n<p>The drugs are marketed under different brand names and are authorised prescription-only medicines in the EU for the treatment of weight management or Type 2 diabetes.<\/p>\n<p>Meanwhile, an expert in obesity management has said that a lot of people were accessing the treatments online without an appropriate prescription.<\/p>\n<p>Speaking on RT\u00c9&#8217;s News at One programme, Professor Donal O&#8217;Shea said people were not sure about what they were getting and were not appropriately counselled about the side effects.<\/p>\n<p>&#8220;When we prescribe these, we say to individuals that it&#8217;s really important to drink plenty, that you keep the fibre in your diet up so you don&#8217;t get constipated,&#8221; he said.<\/p>\n<p>&#8220;If you do start vomiting, you stop them immediately.<\/p>\n<p>&#8220;I think the 1,500 are likely to be the people who are engaged with their healthcare practitioners because it&#8217;s healthcare practitioners that do the reporting to the HPRA.<\/p>\n<p>&#8220;I think there&#8217;s another group that we know exists because I see them in the emergency department. For instance, people who come in with dizziness, people who come in with vomiting and kidney failure.<\/p>\n<p>&#8220;I&#8217;ve seen people admitted to intensive care in our own hospital because of the side effects of these drugs, so it&#8217;s very real,&#8221; he added.<\/p>\n<p alt=\"New figures on the number of people reporting side effects while on an...\" class=\"tpe\" data-description=\"The medicines regulator says it has recorded just over 1500 adverse reactions to the anti-obesity injections known as GLP-1s. Expert in managing obesity, Professor Donal O'Shea talks about some of the side effects he's seen.\" data-embed=\"rte-player\" data-id=\"22636568\" data-ot-category=\"C0004\" data-title=\"The medicines regulator says it has recorded just over 1500 adverse reactions to the anti-obesity injections known as GLP-1s. Expert in managing obesity, Professor Donal O'Shea talks about some of the side effects he's seen.\" id=\"22636568\">We need your consent to load this rte-player contentWe use rte-player to manage extra content that can set cookies on your device and collect data about your activity. Please review their details and accept them to load the content.<a class=\"blocked-button\" href=\"https:\/\/www.rte.ie\/news\/health\/2026\/0811\/1587485-anti-obesity-injections\/javascript:void(0);\" onclick=\"OneTrust.ToggleInfoDisplay()\" rel=\"nofollow noopener\" target=\"_blank\">Manage Preferences<\/a><\/p>\n<p>Mr O&#8217;Shea said that the findings in Ireland were backed up by similar reports in the UK.<\/p>\n<p>&#8220;The side effects are primarily gastrointestinal. They are nausea, constipation, vomiting, and that&#8217;s what this information from the HPRA is saying,&#8221; he said.<\/p>\n<p>&#8220;There\u2019s 1,500 incidents reported. In the UK, I think they\u2019ve had 15,000.<\/p>\n<p>&#8220;The UK is about ten times bigger than we are, so these are real findings backed up by the UK findings.&#8221;<\/p>\n<p>Mr O&#8217;Shea said it was important to take stock of the situation before the drugs become &#8220;a runaway train&#8221;.<\/p>\n<p>Supervision and engagement with a GP or practice nurse is needed when it comes to treatments for obesity, he said.<\/p>\n<p>In a statement to RT\u00c9&#8217;s News at One, the HPRA said it receives reports based on a &#8220;reporter&#8217;s suspicion that an adverse experience may be associated with a medicine and as such, these are referred to as &#8216;suspected&#8217; side effects.<\/p>\n<p>&#8220;The reports of suspected side effects to the HPRA are largely consistent with the known safety profile of the medicines and are described in the medicine product information.&#8221;<\/p>\n<p>&#8220;All known side effects are included in the product information that documents the known safety profile of the medicine.&#8221;<\/p>\n","protected":false},"excerpt":{"rendered":"There have been over 1,500 reports of suspected adverse reactions from weight loss medication, the Health Products Regulatory&hellip;\n","protected":false},"author":2,"featured_media":810428,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[58],"tags":[97,243],"class_list":["post-810427","post","type-post","status-publish","format-standard","has-post-thumbnail","category-medication","tag-health","tag-medication"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/810427","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/comments?post=810427"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/810427\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media\/810428"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media?parent=810427"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/categories?post=810427"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/tags?post=810427"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}